scholarly journals Complete Nucleotide Sequence Analysis of Plasmids in Strains ofStaphylococcus aureusClone USA300 Reveals a High Level of Identity among Isolates with Closely Related Core Genome Sequences

2010 ◽  
Vol 48 (12) ◽  
pp. 4504-4511 ◽  
Author(s):  
Adam D. Kennedy ◽  
Stephen F. Porcella ◽  
Craig Martens ◽  
Adeline R. Whitney ◽  
Kevin R. Braughton ◽  
...  
2019 ◽  
Vol 63 (11) ◽  
Author(s):  
Liang-Xing Fang ◽  
Chong Chen ◽  
Dong-Ling Yu ◽  
Ruan-Yang Sun ◽  
Chao-Yue Cui ◽  
...  

ABSTRACT We reported the complete nucleotide sequence of a tet(X4)-carrying plasmid, pSTB20-1T, from a tigecycline-resistant Escherichia coli isolate in China. Sequence analysis indicated that pSTB20-1T contains a hybrid plasmid backbone and a tet(X4)-containing multidrug resistance region, likely originated through recombination of multiple plasmids. tet(X4) was flanked by two ISCR2, which may be responsible for tet(X4) mobilization. The occurrence and transmission of this novel hybrid plasmid may exacerbate the spread of the clinically significant tet(X4) gene.


2006 ◽  
Vol 74 (9) ◽  
pp. 5408-5413 ◽  
Author(s):  
Carl Brinkley ◽  
Valerie Burland ◽  
Rogéria Keller ◽  
Debra J. Rose ◽  
Adam T. Boutin ◽  
...  

ABSTRACT The complete nucleotide sequence was determined for pMAR7, an enteropathogenic Escherichia coli (EPEC) adherence factor (EAF) plasmid that contains genes encoding a type IV attachment pilus (Bfp) and the global virulence regulator per. Prototypic EAF plasmid pMAR7 is self-transmissible, unlike the smaller EAF plasmid pB171, which has no genes encoding conjugative functions. The tra locus, a highly conserved 33-kb segment found in pMAR7, is similar to the tra (conjugation) region of the F plasmid. ISEc13 copies flanking the pMAR7 tra region could potentially mobilize or delete the tra genes. Hybridization of 134 EPEC strains showed that a complete tra region is present only in strains of the EPEC1 clonal group. This study confirms EPEC's potential for dissemination of virulence attributes by horizontal transfer of the EAF plasmid.


2008 ◽  
Vol 153 (10) ◽  
pp. 1967-1970 ◽  
Author(s):  
C. Cáceres ◽  
V. Yung ◽  
P. Araya ◽  
J. Tognarelli ◽  
E. Villagra ◽  
...  

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