Acid-fast bacilli in sputum: a case of Legionella micdadei pneumonia.

1986 ◽  
Vol 24 (6) ◽  
pp. 1102-1103 ◽  
Author(s):  
E Hilton ◽  
R A Freedman ◽  
F Cintron ◽  
H D Isenberg ◽  
C Singer
Keyword(s):  
Acid Fast Bacilli ◽  
Legionella Micdadei

Community-acquired Legionella micdadei pneumonia presenting as acid fast bacilli in sputum

1991 ◽  
Vol 13 (12) ◽  
pp. 95-96
Author(s):  
Elizabeth Ann Bryce ◽  
Roberta L. Barteluk ◽  
Michael A. Noble ◽  
Pearce G. Wilcox ◽  
Elaine T. Vessuille ◽  
...  
Keyword(s):  
Acid Fast Bacilli ◽  
Legionella Micdadei

Acute Pancreatitis Possibly Caused by Legionella micdadei

1985 ◽  
Vol 17 (2) ◽  
pp. 229-231
Author(s):  
Per Arneborn ◽  
Ingegerd Kallings
Keyword(s):  
Acute Pancreatitis ◽  
Legionella Micdadei

Acid-fast bacilli smear test of a blood culture sample for the diagnosis of disseminated Mycobacterium genavense infection: A case report

2021 ◽  
Vol 32 (5) ◽  
pp. 483-485
Author(s):  
Yo Murata ◽  
Nobuaki Mori ◽  
Narito Kagawa ◽  
Kentaro Okuma ◽  
Shinji Yoshida ◽  
...  
Keyword(s):  
Blood Culture ◽  
Culture Conditions ◽  
Nontuberculous Mycobacterium ◽  
Sequencing Analysis ◽  
Culture Methods ◽  
Smear Test ◽  
Acid Fast Bacilli ◽  
Mycobacterium Genavense ◽  
Old Japanese ◽  
Immunosuppressed Patients

Mycobacterium genavense, a nontuberculous Mycobacterium, is found in immunosuppressed patients, particularly in those with HIV. Mycobacterium genavense incubation under standard culture conditions is difficult, and its identification is challenging using routine culture methods. Herein, we report the case of a 40-year-old Japanese man with HIV presenting with disseminated M. genavense infection. An analysis using an automated blood culture system did not show positive signals during 6 weeks of incubation. However, an acid-fast bacilli smear of his blood sample was positive for the bacterium. Mycobacterium genavense was identified using sequencing analysis, targeting the heat shock protein 65 gene. The patient recovered from the infection, following antibiotic therapy for 18 months. Under suspicion of disseminated M. genavense infection and the absence of bacterial growth in blood culture samples, an acid-fast bacilli smear test of the sample may be useful for timely diagnosis.

Legionnaire’s Disease

2001 ◽  
Vol 58 (10) ◽  
pp. 592-598
Author(s):  
Andreas F. Widmer
Keyword(s):  
Legionella Pneumophila ◽  
Legionnaire's Disease ◽  
Legionnaire’S Disease ◽  
Legionella Micdadei

Legionellen sind Wasserkeime und können zwei typische Krankheitsbilder auslösen: Das Pontiac-Fieber und die Legionärskrankheit. Letztere ist eine seltene (3–7%), potentiell lebensbedrohliche Pneumonie. In fast allen Fällen ist Legionella pneumophila Serogruppe I für die Pneumonie verantwortlich. Es gibt aber 42 Arten und 64 Serotypen, wobei Legionella micdadei der zweithäufigste Erreger ist. Die Letalität der Legionellenpneumonie liegt immer noch um 5% bis 10% und ist bei hospitalisierten Patienten höher. Etablierte Risiken sind Nikotinabusus, chronisch-obstruktive Pneumopathie, sowie Immunsuppression. Die Kultur bedingt Spezialnährmedien, so dass die Diagnose nicht mit Routinemethoden gestellt werden kann. Die Einführung des Antigentestes im Urin hat die Diagnostik wesentlich verbessert. Eine PCR für Sputum ergänzt die neuen diagnostischen Möglichkeiten, wobei hier die Kosten und die Spezifität die Anwendung auf Spezialfälle einschränkt. Therapie der Wahl sind neuere Makrolide oder alternativ neuere Quinolone, die sich vor allem bei transplantierten Patienten auch als Therapie der ersten Wahl durchgesetzt haben. Die Primärprävention umfasst das Halten der Warmwasserversorgung am Boiler bei 60°C, und an Hähnen zwei Minuten nach Öffnen 50°C.

Successful treatment of Legionella micdadei (Pittsburgh pneumonia agent) pneumonia with erythromycin

1981 ◽  
Vol 71 (5) ◽  
pp. 836-840 ◽  
Author(s):  
Edward J. Wing ◽  
Frank J. Schafer ◽  
A.William Pasculle
Keyword(s):  
Successful Treatment ◽  
Legionella Micdadei

scholarly journals Assessment of the BD MGIT TBc Identification Test for the Detection ofMycobacterium tuberculosisComplex in a Network of Mycobacteriology Laboratories

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Diana Machado ◽  
Jorge Ramos ◽  
Isabel Couto ◽  
Nureisha Cadir ◽  
Inácio Narciso ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Sample Preparation ◽  
Nontuberculous Mycobacteria ◽  
Molecular Methods ◽  
Predictive Values ◽  
Acid Fast Bacilli ◽  
Negative Results ◽  
Resource Limited ◽  
Identification Test

We evaluate the performance of the TBcID assay in a panel of 100 acid-fast bacilli cultures. Sixty-four isolates were TBcID positive forMycobacterium tuberculosiscomplex (MTBC), whereas 36 gave negative results. These included 28 nontuberculous mycobacteria, one nonmycobacterial isolate, oneM. tuberculosis, and sixM. bovisBCG strains. This corresponds to a sensitivity of 90.14%, specificity of 100%, and positive and negative predictive values of 100% and 80.55%, respectively. The test is rapid, easy to perform and interpret, and does not require sample preparation or instrumentation. However, a negative result does not exclude the presence of a strain belonging to MTBC, especially when mutations inmpb64gene are present or someM. bovisBCG strains are isolated. The TBcID showed potential to assist in the identification of MTBC when the implementation and usage of molecular methods are often not possible, principally in resource-limited countries.

scholarly journals Natural history ofMycobacterium aviumcomplex lung disease in untreated patients with stable course

2017 ◽  
Vol 49 (3) ◽  
pp. 1600537 ◽  
Author(s):  
Ji An Hwang ◽  
Sunyoung Kim ◽  
Kyung-Wook Jo ◽  
Tae Sun Shim
Keyword(s):  
Body Mass Index ◽  
Natural History ◽  
Lung Disease ◽  
Body Mass ◽  
Initial Diagnosis ◽  
Acid Fast Bacilli ◽  
Sputum Conversion ◽  
History Of ◽  
Negative Sputum ◽  
Systemic Symptoms

Little is known about the long-term natural history ofMycobacterium aviumcomplex lung disease (MAC-LD) in untreated patients with stable course.The aim of this study was to investigate the natural course of untreated stable MAC-LD, with a focus on factors associated with clinical deterioration, spontaneous sputum conversion and prognosis.Of 488 patients diagnosed with MAC-LD between 1998 and 2011, 305 patients (62.5%) showed progressive MAC-LD resulting in treatment initiation within 3 years of diagnosis and 115 patients (23.6%) exhibited stable MAC-LD for at least 3 years with a median follow-up duration of 5.6 years. Patients with stable MAC-LD were more likely to have higher body mass index and less systemic symptoms at initial diagnosis compared with patients with progressive MAC-LD, while positive sputum acid-fast bacilli smear, fibrocavitary type and more extensive disease in radiological findings were more associated with progressive MAC-LD. Of the untreated patients with stable MAC-LD, 51.6% underwent spontaneous sputum conversion, with younger age, higher body mass index and negative sputum acid-fast bacilli smear at initial diagnosis found to be predictors of this occurrence.Advanced age, fibrocavitary type and abnormal pulmonary function were negative prognostic factors for survival in patients with stable MAC-LD.

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