scholarly journals Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages

mBio ◽  
2021 ◽  
Author(s):  
Samantha L. Bell ◽  
Kayla L. Lopez ◽  
Jeffery S. Cox ◽  
Kristin L. Patrick ◽  
Robert O. Watson
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Infectious Diseases ◽  
Tuberculosis Infection ◽  
Harsh Environment ◽  
Intracellular Pathogens ◽  
First Line ◽  
Mycobacterium Tuberculosis Infection ◽  
Content Type ◽  
Selective Autophagy ◽  
Global Population

Mycobacterium tuberculosis (Mtb) infects one-quarter of the global population and causes one of the deadliest infectious diseases worldwide. Macrophages are the first line of defense against Mtb infection and are typically incredibly efficient at destroying intracellular pathogens, but Mtb has evolved to survive and replicate in this harsh environment.

scholarly journals Acute Inflammation Confers Enhanced Protection against Mycobacterium tuberculosis Infection in Mice

2021 ◽  
Author(s):  
Tucker J. Piergallini ◽  
Julia M. Scordo ◽  
Paula A. Pino ◽  
Larry S. Schlesinger ◽  
Jordi B. Torrelles ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Mycobacterium Tuberculosis ◽  
Causative Agent ◽  
Acute Inflammation ◽  
Causes Of Death ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Content Type ◽  
High Level ◽  
Tuberculosis Disease

Mycobacterium tuberculosis , the causative agent of tuberculosis disease, is estimated to infect one-fourth of the world’s population and is one of the leading causes of death due to an infectious disease worldwide. The high-level variability in tuberculosis disease responses in the human populace may be linked to immune processes related to inflammation.

scholarly journals Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection.

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Noria Segueni ◽  
Sulayman Benmerzoug ◽  
Stéphanie Rose ◽  
Amandine Gauthier ◽  
Marie-Laure Bourigault ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Myeloid Cell ◽  
Tuberculosis Infection ◽  
First Line ◽  
Mycobacterium Tuberculosis Infection

scholarly journals Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to Mycobacterium tuberculosis infection

Virulence ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 1227-1238
Author(s):  
Nathan Scott Kieswetter ◽  
Mumin Ozturk ◽  
Shelby-Sara Jones ◽  
Sibusiso Senzani ◽  
Melissa Dalcina Chengalroyen ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Host Immune Response ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection
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