scholarly journals Technology Advances, High-Risk Research, and a Safe Way Forward

mBio ◽  
2021 ◽  
Vol 12 (5) ◽  
Author(s):  
David R. Franz ◽  
James W. Le Duc

The human and economic toll of the coronavirus disease 2019 (COVID-19) pandemic and the unknowns regarding the origins of the virus, with a backdrop of enormous advances in technologies and human understanding of molecular virology, have raised global concerns about the safety of the legitimate infectious disease research enterprise. We acknowledge the safety and security risks resulting from the broad availability of tools and knowledge, tools and knowledge that can be exploited equally for good or harm.

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Hee-Gyeong Yi ◽  
Hyeonji Kim ◽  
Junyoung Kwon ◽  
Yeong-Jin Choi ◽  
Jinah Jang ◽  
...  

AbstractRapid development of vaccines and therapeutics is necessary to tackle the emergence of new pathogens and infectious diseases. To speed up the drug discovery process, the conventional development pipeline can be retooled by introducing advanced in vitro models as alternatives to conventional infectious disease models and by employing advanced technology for the production of medicine and cell/drug delivery systems. In this regard, layer-by-layer construction with a 3D bioprinting system or other technologies provides a beneficial method for developing highly biomimetic and reliable in vitro models for infectious disease research. In addition, the high flexibility and versatility of 3D bioprinting offer advantages in the effective production of vaccines, therapeutics, and relevant delivery systems. Herein, we discuss the potential of 3D bioprinting technologies for the control of infectious diseases. We also suggest that 3D bioprinting in infectious disease research and drug development could be a significant platform technology for the rapid and automated production of tissue/organ models and medicines in the near future.


2015 ◽  
Vol 3 ◽  
Author(s):  
James C. Bartholomew ◽  
Andrew D. Pearson ◽  
Nils Chr. Stenseth ◽  
James W. LeDuc ◽  
David L. Hirschberg ◽  
...  

Science ◽  
2015 ◽  
Vol 349 (6252) ◽  
pp. 1259504-1259504 ◽  
Author(s):  
P. T. J. Johnson ◽  
J. C. de Roode ◽  
A. Fenton

2019 ◽  
Vol 20 (6) ◽  
pp. 323-340 ◽  
Author(s):  
Maria A. Spyrou ◽  
Kirsten I. Bos ◽  
Alexander Herbig ◽  
Johannes Krause

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Şenay Kafkas ◽  
Marwa Abdelhakim ◽  
Yasmeen Hashish ◽  
Maxat Kulmanov ◽  
Marwa Abdellatif ◽  
...  

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