scholarly journals Genome Sequences of Seven Foot-and-Mouth Disease Virus Isolates Reveal Diversity in the O/ME-SA/Ind2001 Lineage in India between 1997 and 2009

2020 ◽  
Vol 9 (16) ◽  
Author(s):  
Miranda R. Bertram ◽  
Rachel M. Palinski ◽  
Steven J. Pauszek ◽  
Ethan J. Hartwig ◽  
George R. Smoliga ◽  
...  

We report the genome sequences of seven foot-and-mouth disease (FMD) virus (FMDV) isolates collected in India between 1997 and 2009. The strains represented four sublineages within the O/ME-SA/Ind2001 lineage. These viruses provide insights into FMDV diversity and evolution in India and may influence future control measures, including vaccine selections.

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Miranda R. Bertram ◽  
Barbara Brito ◽  
Rachel M. Palinski ◽  
Ian H. Fish ◽  
Steven J. Pauszek ◽  
...  

ABSTRACT We report the genome sequences of 12 recombinant foot-and-mouth disease virus isolates from Vietnam. The recombinant strain has a capsid region from an A/Sea-97 strain and a nonstructural segment from an O/ME-SA/PanAsia strain. The isolates were obtained from two outbreak samples collected in June 2017 and 10 subclinical samples collected between 2017 and 2019.


2018 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Barbara Brito ◽  
Steven J Pauszek ◽  
Ethan J Hartwig ◽  
George R Smoliga ◽  
Le T Vu ◽  
...  

1975 ◽  
Vol 75 (3) ◽  
pp. 387-397 ◽  
Author(s):  
Ann E. M. Arrowsmith

SUMMARYVariants of type A FMD virus from the Eastern Mediterranean region over the years 1964–72 have been shown to belong to a group distinct from the Western European strains as represented by A5 Westerwald. This group appears to derive from the A22 strain first recognized in 1964 and indicates the possibility of new strains supplanting old in the field.


PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e49650 ◽  
Author(s):  
Begoña Valdazo-González ◽  
Lilyana Polihronova ◽  
Tsviatko Alexandrov ◽  
Preben Normann ◽  
Nick J. Knowles ◽  
...  

Author(s):  
Chi Mai Duong

The aim of this study was to assess the seroprevalence against serotype O FMD (foot and mouth disease) virus in vaccinated pigs and cattle in Ho Chi Minh City, as a basis to serve the prevention of FMD epidemics in these animals. A total of 535 pigs and 366cattle sera were tested by using the Elisa kit for the detection of serotype O FMD antibody (Pirbright, UK). Results of this study showed that most pig farms had the proportions of positive animals for antibodies against FMDV serotype O which met the requirements of Decision no. 07/2016/ Ministry of Agriculture and Rural Development, except Xuan Thoi Thuong, Thai My and Phu My Hung. All sows had high levels of antibodies against serotype O FMD virus. There were no significant differences in the ratios of positive pigs for antibodies against FMDV serotype O among types of pig and age groups. However, there were significant differences in the seroprevalence of vaccinated pigs across herd sizes and days post-vaccination. Meanwhile, the overall seroprevalence of vaccinated cattle against FMDV at individual-level was over 80.00%. No statistical differences were found in the seroprevalence of vaccinated cattle against type OFMDV among regions, types of cattle, herd sizes, age groups and days post-vaccination. In conclusion, pigs raised in farms of Xuan Thoi Thuong, Thai My and Phu My Hung communes should be revaccinated with FMD vaccine to prevent the risk of pigs being infected with FMD virus and reduce the amount of virus produced by an infected animal.


Vaccine ◽  
1990 ◽  
Vol 8 (4) ◽  
pp. 390-396 ◽  
Author(s):  
A.R. Samuel ◽  
E.J. Ouldridge ◽  
A.E.M. Arrowsmith ◽  
R.P. Kitching ◽  
N.J. Knowles

2021 ◽  
Vol 344 (1) ◽  
pp. 20-23
Author(s):  
A. V. Mishchenko ◽  
V. A. Mishchenko ◽  
O. Yu. Chernykh ◽  
R. A. Krivonos ◽  
A. A. Lysenko

The analysis of the results of epizootic investigations carried out in the foci of foot and mouth disease and data from the study of the role of meat, meat products, meat processing waste and non-neutralized kitchen waste in the spread of the foot and mouth disease virus in a number of European countries (England, Belgium, Greece, Italy, Germany and Switzerland), the Soviet Union (Kyrgyz SSR, Latvian SSR, Magadan, Sakhalin, Leningrad and Kamchatka regions), Russian Federation (1995). Outbreaks of foot and mouth disease in Mongolia in February - March were caused by the transport of susceptible animals infected with foot and mouth disease virus and their slaughter products on the eve of the religious New Year holiday [1, 10]. Recently, the Russian Federation is free from foot and mouth disease. However, cases of the introduction of the FMD virus from neighboring countries unfavorable for this infection are recorded [8]. The greatest danger is posed by meat obtained from the slaughter of animals during the incubation period, as well as from vaccinated cattle infected with the FMD virus [2830]. The article presents the results of the indication of the FMD virus in samples from different organs and tissues infected with the FMD virus of animals. Information about the modes of disinfection of meat and meat products is presented.


2022 ◽  
Vol 19 (1) ◽  
Author(s):  
Ayah M. Hassan ◽  
Mostafa R. Zaher ◽  
Rabab T. Hassanien ◽  
Mervat I. Abd-El-Moniem ◽  
Ahmed R. Habashi ◽  
...  

Abstract Background Surveillance for circulating emerging diseases of economic importance has a major role in the rapid response to major pathogen outbreaks. Foot-and-mouth disease virus (FMDV) is one of the significant endemic viruses in Egypt. FMDV is periodically investigated for monitoring evolution and emergence of new variants. The genetic characterization of foot-and-mouth disease (FMD) virus serotype A responsible for recent outbreaks of FMD in Egypt was determined. Methods Samples were collected from different locations and virus isolation was performed using BHK-21 cells. Viral RNA was extracted and samples were screened for FMDV using real-time RT-PCR. DNA sequence analysis was performed and computational and bioinformatics analyses were used to determine the substitution rates and phylogenetic relationship. Results Sequence and phylogenetic analyses of full-length 1D region of FMDV samples collected from different governorates in 2020 showed close similarity to Egyptian FMDV strains from serotype A-African topotype-G-IV with genetic variation of 6.5%. Recently isolated FMDV strains showed high genetic variations from locally used vaccine strains in the major antigenic sites of VP1 region. Conclusions Although, efforts made by the veterinary authorities to implement an effective mass vaccination plan, the recently detected FMDV strains in this study could not be subtyped using the FMDV primers routinely used for molecular serotyping. These dissimilarities raise the alarm for reconsideration of the FMDV isolates used in vaccine manufacture. Clearly close monitoring of FMD in Egypt is urgently required to define the risks of future outbreaks and to ensure appropriate control measures against FMD major outbreaks.


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