scholarly journals Complete Genome Sequence of Klebsiella pneumoniae Myophage Magnus

2019 ◽  
Vol 8 (39) ◽  
Author(s):  
Laura E. Acevedo Ugarriza ◽  
Jordyn Michalik-Provasek ◽  
Heather Newkirk ◽  
Mei Liu ◽  
Jason J. Gill ◽  
...  

Bacteriophage Magnus infects Klebsiella pneumoniae, a Gram-negative pathogen whose multidrug-resistant strains are a public health issue. Here, we describe the annotation of the 157,741-bp Magnus genome and its similarity to other myophages.

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Travis J. Kochan ◽  
Egon A. Ozer ◽  
Nathan B. Pincus ◽  
Margaret A. Fitzpatrick ◽  
Alan R. Hauser

Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.


2019 ◽  
Vol 8 (19) ◽  
Author(s):  
Katherine T. Nguyen ◽  
Rachele Bonasera ◽  
Garret Benson ◽  
Adriana C. Hernandez-Morales ◽  
Jason J. Gill ◽  
...  

May is a newly isolated myophage that infects multidrug-resistant strains of Klebsiella pneumoniae, a pathogen that is associated with antibiotic-resistant infections in humans. The genome of May has been shown to be similar to that of phage Vi01.


2019 ◽  
Vol 8 (21) ◽  
Author(s):  
Rainie Tran ◽  
Rohit Kongari ◽  
Lauren Lessor ◽  
Jason J. Gill ◽  
Mei Liu

Klebsiella pneumoniae infection is a serious concern in hospital settings due to the continuing emergence of multidrug-resistant strains. The study of K. pneumoniae phages may help the development of new treatment strategies.


2021 ◽  
Vol 10 (4) ◽  
Author(s):  
Daniel Mora ◽  
Lauren Lessor ◽  
Tram Le ◽  
James Clark ◽  
Jason J. Gill ◽  
...  

ABSTRACT Bacteriophage Miami infects Klebsiella pneumoniae, a Gram-negative pathogen that is becoming an increasing threat to public health due to its multidrug resistance. Here, we describe the annotation of the 253,383-bp jumbo phage Miami genome sequence and its similarity to other myophages.


2021 ◽  
Vol 10 (21) ◽  
Author(s):  
Johnathan Lo ◽  
Lauren Lessor ◽  
James Clark ◽  
Tram Le ◽  
Jason J. Gill ◽  
...  

Klebsiella pneumoniae is a Gram-negative pathogen that has become increasingly antibiotic resistant. Phage therapy is potentially a useful approach to control this pathogen. Here, we present the genome sequence of the phiKMV-like K. pneumoniae podophage Pone.


2019 ◽  
Vol 8 (40) ◽  
Author(s):  
Russell Moreland ◽  
Abby Korn ◽  
Heather Newkirk ◽  
Mei Liu ◽  
Jason J. Gill ◽  
...  

Multidrug-resistant strains of Staphylococcus aureus cause serious human disease worldwide. Bacteriophages offer a promising alternative to traditional antibiotics. Here, we announce the 141,712-bp genome of S. aureus phage Maine. A myophage with 9,019-bp predicted terminal repeats and high similarity to other Staphylococcus phages, Maine falls into the Twort-like group.


2019 ◽  
Vol 8 (39) ◽  
Author(s):  
Jacob Gramer ◽  
Sarah Kenny ◽  
Heather Newkirk ◽  
Mei Liu ◽  
Jason J. Gill ◽  
...  

Klebsiella pneumoniae is a Gram-negative opportunistic pathogen and a leading cause of antibiotic-resistant nosocomial infections. The genome sequence of siphophage Skenny, which infects K. pneumoniae, is described here. Skenny encodes 78 genes and is closely related to Klebsiella phages KPN N141 and MezzoGao, which are T1-like phages.


2015 ◽  
Vol 3 (5) ◽  
Author(s):  
Vincent E. Provasek ◽  
Lauren E. Lessor ◽  
Jesse L. Cahill ◽  
Eric S. Rasche ◽  
Gabriel F. Kuty Everett

Klebsiella pneumoniaeis a leading cause of nosocomial infections in the United States. Due to the emergence of multidrug-resistant strains, phages targetingK. pneumoniaemay be a useful alternative against this pathogen. Here, we announce the complete genome ofK. pneumoniaepseudo-T-even myophage Matisse and describe its features.


2017 ◽  
Vol 5 (27) ◽  
Author(s):  
Adam Heikal ◽  
Ørjan Samuelsen ◽  
Tom Kristensen ◽  
Ole Andreas Økstad

ABSTRACT Multidrug-resistant Klebsiella pneumoniae is a major cause of hospital-acquired infections. Here, we report the complete genome sequence of the multidrug-resistant, bla NDM-1-positive strain K. pneumoniae K66-45, isolated from a hospitalized Norwegian patient.


2019 ◽  
Vol 8 (46) ◽  
Author(s):  
Adam J. Salazar ◽  
Lauren Lessor ◽  
Chandler O’Leary ◽  
Jason Gill ◽  
Mei Liu

Carbapenemase-producing Klebsiella pneumoniae poses a significant public health threat due to its resistance to antibiotics. Siphophage Seifer was isolated and characterized as part of an effort to develop phage therapeutics to control this pathogen. This report describes the complete genome sequence of phage Seifer, which is a distant member of the χ-like siphovirus phage cluster.


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