scholarly journals Identification and Characterization of Human Norovirus NTPase Regions Required for Lipid Droplet Localization, Cellular Apoptosis, and Interaction with the Viral P22 Protein

Author(s):  
Ju-Bei Yen ◽  
Lee-Wen Chen ◽  
Ling-Huei Wei ◽  
Chien-Hui Hung ◽  
Shie-Shan Wang ◽  
...  

Human noroviruses (HuNVs) are the major agent of global gastroenteritis outbreaks. However, due to the lack of an efficient cell culture system for HuNV propagation, functions of the viral-encoded proteins in host cells are still poorly understood.

2012 ◽  
Vol 93 (3) ◽  
pp. 618-623 ◽  
Author(s):  
Victoria Sherwood ◽  
Elizabeth King ◽  
Sabine Tötemeyer ◽  
Ian Connerton ◽  
Kenneth H. Mellits

Exposure to interferon results in the rapid transcriptional induction of genes, many of which function to create an antiviral environment in potential host cells. For the majority of adenoviruses, replication is unaffected by the actions of interferon. It has previously been shown, using non-gastrointestinal cells, that the species F human adenoviruses are sensitive to the action of interferon. Here, we have developed an enterocyte-like cell-culture model to re-evaluate this question, and determined the effects of interferon on species F adenovirus during infection of gastrointestinal cells. We show that species F adenovirus type 40 is sensitive to the effects of interferon in gastrointestinal-like cells, which may help to explain its fastidious growth in culture.


2019 ◽  
Vol 31 (3) ◽  
pp. 244-258
Author(s):  
Selvaraj Sivakumar ◽  
T. Raja Swaminathan ◽  
Raj Kumar ◽  
Natarajan Kalaimani

2002 ◽  
Vol 32 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Hye Jin PARK ◽  
Kwang Sik LEE ◽  
Eun Sook CHO ◽  
Eun Young YUN ◽  
Seok Woo KANG ◽  
...  

2016 ◽  
Vol 132 ◽  
pp. 46-49 ◽  
Author(s):  
Abimbola O. Kolawole ◽  
Joana Rocha-Pereira ◽  
Michael D. Elftman ◽  
Johan Neyts ◽  
Christiane E. Wobus

Biosensors ◽  
2015 ◽  
Vol 5 (3) ◽  
pp. 513-536 ◽  
Author(s):  
Sebastian Bonk ◽  
Marco Stubbe ◽  
Sebastian Buehler ◽  
Carsten Tautorat ◽  
Werner Baumann ◽  
...  

2020 ◽  
Vol 15 (5) ◽  
pp. 055007 ◽  
Author(s):  
Ina Gerhild Siller ◽  
Anton Enders ◽  
Pia Gellermann ◽  
Steffen Winkler ◽  
Antonina Lavrentieva ◽  
...  

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