Excitation wave propagation in a patterned multidomain cardiac tissue

JETP Letters ◽  
2015 ◽  
Vol 101 (11) ◽  
pp. 772-775
Author(s):  
N. N. Kudryashova ◽  
A. S. Teplenin ◽  
Y. V. Orlova ◽  
K. I. Agladze
2019 ◽  
Vol 33 (16) ◽  
pp. 1950165 ◽  
Author(s):  
Fan Li ◽  
Linwei Guo

Stable wave propagation is important for heart health, however, the electromagnetic radiation could affect normal signal propagation of heart, even make a sudden cardiac arrest. In this paper, the effect of electromagnetic radiation on the propagation of stable target wave generated by linear feedback control is studied in detail. It is confirmed that there are different transitions of electrical activities in cardiac tissue, which are transitions from target wave to spiral wave, some isolated islands of pattern waves coexisted, broken pattern and even the quiescent state, are generated when the electromagnetic field is imposed on the cardiac tissue in three ways. Furthermore, it is interesting to find there are different real affected regions, in which the electrical activities of nodes are destroyed, when the radiation signal is imposed on the cardiac tissue in different ways. It is also found the kinds of dynamical behaviors in the media are dependent on the real affected region. These results state that electromagnetic radiation could change the electrical activities, even destroy and suppress the wave propagation of wave source, and the ways of electromagnetic radiation imposed on the media are also important.


2000 ◽  
Vol 279 (4) ◽  
pp. H1869-H1879 ◽  
Author(s):  
Thomas J. Hund ◽  
Niels F. Otani ◽  
Yoram Rudy

In a sufficiently short reentry pathway, the excitation wave front (head) propagates into tissue that is partially refractory (tail) from the previous action potential (AP). We incorporate a detailed mathematical model of the ventricular myocyte into a one-dimensional closed pathway to investigate the effects of head-tail interaction and ion accumulation on the dynamics of reentry. The results were the following: 1) a high degree of head-tail interaction produces oscillations in several AP properties; 2) Ca2+-transient oscillations are in phase with AP duration oscillations and are often of greater magnitude; 3) as the wave front propagates around the pathway, AP properties undergo periodic spatial oscillations that produce complicated temporal oscillations at a single site; 4) depending on the degree of head-tail interaction, intracellular [Na+] accumulation during reentry either stabilizes or destabilizes reentry; and 5) elevated extracellular [K+] destabilizes reentry by prolonging the tail of postrepolarization refractoriness.


2001 ◽  
Vol 80 (3) ◽  
pp. 1195-1209 ◽  
Author(s):  
Oleg V. Aslanidi ◽  
Oleg A. Mornev ◽  
Ole Skyggebjerg ◽  
Per Arkhammar ◽  
Ole Thastrup ◽  
...  

2003 ◽  
Vol 13 (12) ◽  
pp. 3605-3619 ◽  
Author(s):  
V. N. BIKTASHEV

An excitation wave in nerve or cardiac tissue may fail to propagate if the temporal gradient of the transmembrane voltage at the front becomes too small to excite the tissue ahead of it. A simplified mathematical model is suggested, that reproduces this phenomenon and has exact traveling front solutions. The spectrum of possible propagation speeds is bounded from below. This causes a front to dissipate if it is not allowed to propagate quickly enough. A crucial role is played by the Na inactivation gates, even if their dynamics are by an order of magnitude slower than the dynamics of the voltage.


1992 ◽  
Vol 59 (4) ◽  
pp. 275-296 ◽  
Author(s):  
Boris Y. Kogan ◽  
Walter J. Karplus ◽  
Brian S. Billett ◽  
William G. Stevenson

2009 ◽  
Author(s):  
Richard R. Bouchard ◽  
Patrick D. Wolf ◽  
Stephen J. Hsu ◽  
Douglas M. Dumont ◽  
Gregg E. Trahey

Sign in / Sign up

Export Citation Format

Share Document