Estimating the Limiting Rate of Dilution in Technology for Lactic Acid Production by Continuous Fermentation

2018 ◽  
Vol 52 (1) ◽  
pp. 64-66 ◽  
Author(s):  
Yu. L. Gordeeva ◽  
A. V. Borodin ◽  
L. S. Gordeev
Keyword(s):  
Lactic Acid ◽  
Acid Production ◽  
Continuous Fermentation ◽  
Lactic Acid Production

A new method studying the kinetics of l-lactic acid production by pellets Rhizopus oryzae in semi-continuous fermentation

2014 ◽  
Vol 65 (3) ◽  
pp. 1473-1480 ◽  
Author(s):  
Xuefeng Wu ◽  
Shaotong Jiang ◽  
Min Zhang ◽  
Shuizhong Luo ◽  
Xingjiang Li ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Acid Production ◽  
Rhizopus Oryzae ◽  
Continuous Fermentation ◽  
Lactic Acid Production ◽  
New Method ◽  
Kinetics Of

Economical D-Lactic Acid Production From Agricultural Residues By Membrane Integrated Continuous Fermentation Coupled With B Vitamin Supplementation

2021 ◽  
Author(s):  
Kedong Ma ◽  
Yubo Cui ◽  
Ke Zhao ◽  
Yuxuang Yang ◽  
Yidan Wang ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lignocellulosic Biomass ◽  
Acid Production ◽  
Continuous Fermentation ◽  
Lactic Acid Production ◽  
Industrial Scale ◽  
Vitamin Supplementation ◽  
Market Demand ◽  
Fermentation Efficiency ◽  
B Vitamin

Abstract Background: D-lactic acid played an important role in the establishment of PLA as a substitute for petrochemical plastics. But, so far, the D-lactic acid production was limited in only pilot scale, which was definitely unable to meet the fast growing market demand. To achieve industrial scale D-lactic acid production, the cost-associated problems such as high-cost feedstock, expensive nutrient sources and fermentation technology need to be resolved to establish an economical fermentation process.Results: In the present study, the combined effect of B vitamin supplementation and membrane integrated continuous fermentation on D-lactic acid production from agricultural lignocellulosic biomass by Lactobacillus delbrueckii was investigated. The results indicated the specific addition of vitamins B1, B2, B3 and B5 could reduce the yeast extract (YE) addition from 10 g/l to 3 g/l without obvious influence on fermentation efficiency. By employing cell recycling system in 350 h continuous fermentation with B vitamin supplementation, YE addition was further reduced to 0.5 g/l, which resulted in nutrient source cost reduction of 86%. A maximum D-lactate productivity of 18.56 g/l/h and optical purity of 99.5% were achieved and higher than most recent reports. Conclusion: These findings suggested the novel fermentation strategy proposed could effectively reduce the production cost and improve fermentation efficiency, thus exhibiting great potential in promoting industrial scale D-lactic acid production from lignocellulosic biomass.

Mathematical Modeling of Continuous Fermentation in Lactic Acid Production

2019 ◽  
Vol 53 (4) ◽  
pp. 501-508
Author(s):  
Yu. L. Gordeeva ◽  
A. G. Borodkin ◽  
E. L. Gordeeva ◽  
E. G. Rudakovskaya
Keyword(s):  
Mathematical Modeling ◽  
Lactic Acid ◽  
Acid Production ◽  
Continuous Fermentation ◽  
Lactic Acid Production
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