Identification of the Side Population Associated with ATP-Binding Cassette Transporters Activity Using Imaging Flow Cytometry

2021 ◽  
Vol 15 (3) ◽  
pp. 248-254
Author(s):  
A. M. Gisina ◽  
Y. S. Kim ◽  
K. N. Yarygin ◽  
A. Yu. Lupatov
Keyword(s):  
Flow Cytometry ◽  
Side Population ◽  
Atp Binding ◽  
Imaging Flow Cytometry ◽  
Atp Binding Cassette Transporters ◽  
Atp Binding Cassette

Identification of the side population associated with ATP-binding cassette transporters activity using imaging flow cytometry

2021 ◽  
Vol 67 (2) ◽  
pp. 137-143
Author(s):  
A.M. Gisina ◽  
Y.S. Kim ◽  
K.N. Yarygin ◽  
A.Yu. Lupatov
Keyword(s):  
Flow Cytometry ◽  
Side Population ◽  
Flow Cytometer ◽  
Atp Binding ◽  
Tumor Resistance ◽  
Side Population Cells ◽  
Imaging Flow Cytometry ◽  
Atp Binding Cassette Transporters ◽  
Resistance To Chemotherapy ◽  
Atp Binding Cassette

DyeCycle Violet efflux, caused by ATP-binding cassette transporters activity, was analyzed in human colorectal adenocarcinoma cell lines SW480, HT-29, Caco-2 by neans of FACSAria III flow cytometer and ImageStreamX Mk II imaging flow cytometer. Along with similarity of cytometry data obtained on the two instruments, the use of imaging flow cytometry made it possible to characterize the morphology of side population cells, as well as morphology of other cell populations differing in the degree of dye accumulation. The population of cells, which are smaller than the side population cells and practically do not take the dye, is of the special interest. Probably, this population may contribute to the tumor resistance to chemotherapy.

scholarly journals Stimulation of Cholesterol Excretion by the Liver X Receptor Agonist Requires ATP-binding Cassette Transporters G5 and G8

2003 ◽  
Vol 278 (18) ◽  
pp. 15565-15570 ◽  
Author(s):  
Liqing Yu ◽  
Jennifer York ◽  
Klaus von Bergmann ◽  
Dieter Lutjohann ◽  
Jonathan C. Cohen ◽  
...  
Keyword(s):  
Receptor Agonist ◽  
Liver X Receptor ◽  
Atp Binding ◽  
Atp Binding Cassette Transporters ◽  
Cholesterol Excretion ◽  
Liver X Receptor Agonist ◽  
Stimulation Of ◽  
Atp Binding Cassette

scholarly journals Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro

2013 ◽  
Vol 136 (2) ◽  
pp. 382-391 ◽  
Author(s):  
Anita C. A. Dankers ◽  
Maarke J. E. Roelofs ◽  
Aldert H. Piersma ◽  
Fred C. G. J. Sweep ◽  
Frans G. M. Russel ◽  
...  
Keyword(s):  
Endocrine Disruptors ◽  
Leydig Cell ◽  
Atp Binding ◽  
Testosterone Secretion ◽  
Atp Binding Cassette Transporters ◽  
Blood Testis Barrier ◽  
Atp Binding Cassette
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