SAT0387 Visualization of cartilage as a new imaging biomarker for the quantification of joint damage in rheumatoid arthritis using DGEMRIC and T2-mapping in high-resolution magnet resonance imaging

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 602.3-603
Author(s):  
B. Herz ◽  
S. Finzel ◽  
A. Albrecht ◽  
J. Rech ◽  
M. Englbrecht ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
High Resolution ◽  
T2 Mapping ◽  
Joint Damage ◽  
Imaging Biomarker ◽  
Resonance Imaging ◽  
Magnet Resonance Imaging ◽  
Magnet Resonance

scholarly journals The Relationship Between Synovial Pathobiology and Magnetic Resonance Imaging Abnormalities in Rheumatoid Arthritis: A Systematic Review

2017 ◽  
Vol 44 (9) ◽  
pp. 1311-1324 ◽  
Author(s):  
Frances Humby ◽  
Arti Mahto ◽  
Muaaze Ahmed ◽  
Andrew Barr ◽  
Stephen Kelly ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Resonance Imaging ◽  
Systematic Review ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Bone Erosion ◽  
Critical Role ◽  
Joint Damage ◽  
Resonance Imaging ◽  
The Relationship

Objective.Magnetic resonance imaging (MRI) has been increasingly recognized as a critical tool for the assessment of patients with rheumatoid arthritis (RA) and is able to reliably identify synovitis, bone marrow edema, bone erosion, and joint space narrowing (JSN)/cartilage loss. Understanding the exact relationship between each MRI feature and local synovial pathobiology is critical to dissect disease pathogenesis as well as develop future predictive models.Methods.A systematic review was performed of the current published literature examining the relationship between MRI abnormalities and synovial pathobiology in patients with RA.Results.Eighteen studies were identified; most focused on validation of MRI as a tool to detect and quantify synovitis, with a significant relationship demonstrated. Additionally, from the limited data available, a critical role seems likely for synovial pathways, at least in driving joint damage. However, there was a lack of data examining the relationship between synovial pathobiology and bone marrow abnormalities and JSN.Conclusion.Although understanding the interrelationship of these disease biomarkers offers the potential to enhance the predictive validity of modern imaging with concomitant synovial pathobiological analysis, further studies integrating MRI with synovial tissue analysis in well-controlled cohorts at distinct disease stages before and after therapeutic intervention are required to achieve this.

scholarly journals Additive Value of Transrectal Systematic Ventral Biopsies in Combination with Magnet Resonance Imaging/Ultrasound Fusion-Guided Biopsy in Patients with 3 or More Negative Prostate Biopsies

2019 ◽  
Vol 104 (3-4) ◽  
pp. 205-213
Author(s):  
Andreas Maxeiner ◽  
Alexander M. Nest ◽  
Carsten Stephan ◽  
Hannes Cash ◽  
Alexander D.J. Baur ◽  
...  
Keyword(s):  
Resonance Imaging ◽  
Magnet Resonance Imaging ◽  
Prostate Biopsies ◽  
Guided Biopsy ◽  
Magnet Resonance
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