OP0222 Inactivation of Urokinase-Type Plasminogen Activator Receptor Induces Dermal and Pulmonary Fibrosis and Peripheral Microvasculopathy in Mice Closely Resembling Human Systemic Sclerosis

Domain 1 of the urokinase-type plasminogen activator receptor is required for its morphologic and functional, β2 integrin–mediated connection with actin cytoskeleton in human microvascular endothelial cells: Failure of association in systemic sclerosis endothelial cells

Arthritis & Rheumatism ◽

10.1002/art.22263 ◽

2006 ◽

Vol 54 (12) ◽

pp. 3926-3938 ◽

Cited By ~ 52

Author(s):

Francesca Margheri ◽

Mirko Manetti ◽

Simona Serratì ◽

Daniele Nosi ◽

Marco Pucci ◽

...

Keyword(s):

Endothelial Cells ◽

Systemic Sclerosis ◽

Actin Cytoskeleton ◽

Plasminogen Activator ◽

Microvascular Endothelial Cells ◽

Β2 Integrin ◽

Plasminogen Activator Receptor ◽

Microvascular Endothelial

Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-203706 ◽

2013 ◽

Vol 73 (9) ◽

pp. 1700-1709 ◽

Cited By ~ 51

Author(s):

Mirko Manetti ◽

Irene Rosa ◽

Anna Franca Milia ◽

Serena Guiducci ◽

Peter Carmeliet ◽

...

Keyword(s):

Pulmonary Fibrosis ◽

Plasminogen Activator ◽

New Model ◽

Faculty Opinions recommendation of Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718030853.793491108 ◽

2014 ◽

Author(s):

Jörg Distler ◽

Rosebeth Kagwiria

Keyword(s):

Pulmonary Fibrosis ◽

Plasminogen Activator ◽

New Model ◽

Urokinase-type plasminogen activator receptor

AfCS-Nature Molecule Pages ◽

10.1038/mp.a004089.01 ◽

2009 ◽

Author(s):

Nicolai Sidenius ◽

Francesco Blasi

Keyword(s):

Plasminogen Activator ◽

Urokinase-Type Plasminogen Activator Receptor Modulates Epileptogenesis in Mouse Model of Temporal Lobe Epilepsy

Molecular Neurobiology ◽

10.1007/s12035-012-8386-2 ◽

2012 ◽

Vol 47 (3) ◽

pp. 914-937 ◽

Cited By ~ 29

Author(s):

Xavier Ekolle Ndode-Ekane ◽

Asla Pitkänen

Keyword(s):

Mouse Model ◽

Temporal Lobe Epilepsy ◽

Plasminogen Activator ◽

Temporal Lobe ◽

Plasma Soluble Urokinase-Type Plasminogen Activator Receptor Is Not Associated with Neurological Outcome in Patients with Aneurysmal Subarachnoid Hemorrhage

Frontiers in Neurology ◽

10.3389/fneur.2017.00144 ◽

2017 ◽

Vol 8 ◽

Cited By ~ 1

Author(s):

Heikki Kiiski ◽

Ville Jalkanen ◽

Marika Ala-Peijari ◽

Mari Hämäläinen ◽

Eeva Moilanen ◽

...

Keyword(s):

Subarachnoid Hemorrhage ◽

Plasminogen Activator ◽

Neurological Outcome ◽

Aneurysmal Subarachnoid Hemorrhage ◽

Explore the role of lymphocyte antigen 6/urokinase-type plasminogen activator receptor related protein-1 in melanoma promoting caused by signaling of α7-nicotinic acetylcholine receptors

Journal of the Neurological Sciences ◽

10.1016/j.jns.2017.08.3497 ◽

2017 ◽

Vol 381 ◽

pp. 456-457

Author(s):

P.J. Lin ◽

S.H. Jee ◽

C.Y. Chang

Keyword(s):

Plasminogen Activator ◽

Nicotinic Acetylcholine Receptors ◽

Acetylcholine Receptors ◽

Related Protein ◽

Nicotinic Acetylcholine ◽

Α7 Nicotinic Acetylcholine Receptors ◽

The murine urokinase-type plasminogen activator receptor gene

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)47149-9 ◽

1994 ◽

Vol 269 (42) ◽

pp. 25992-25998

Author(s):

T T Suh ◽

C Nerlov ◽

K Danø ◽

J L Degen

Keyword(s):

Plasminogen Activator ◽

Receptor Gene ◽

Urokinase-type Plasminogen Activator Receptor Regulates a Novel Pathway of Fibronectin Matrix Assembly Requiring Src-dependent Transactivation of Epidermal Growth Factor Receptor

Journal of Biological Chemistry ◽

10.1074/jbc.m501901200 ◽

2006 ◽

Vol 281 (14) ◽

pp. 9450-9459 ◽

Cited By ~ 36

Author(s):

Elizabeth Monaghan-Benson ◽

Paula J. McKeown-Longo

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Plasminogen Activator ◽

Growth Factor Receptor ◽

Matrix Assembly ◽

Epidermal Growth ◽

Cell Signaling by Urokinase-type Plasminogen Activator Receptor Induces Stem Cell–like Properties in Breast Cancer Cells

Cancer Research ◽

10.1158/0008-5472.can-10-1936 ◽

2010 ◽

Vol 70 (21) ◽

pp. 8948-8958 ◽

Cited By ~ 58

Author(s):

Minji Jo ◽

Boryana M. Eastman ◽

Drue L. Webb ◽

Konstantin Stoletov ◽

Richard Klemke ◽

...

Keyword(s):

Breast Cancer ◽

Stem Cell ◽

Cell Signaling ◽

Cancer Cells ◽

Plasminogen Activator ◽

Breast Cancer Cells ◽