scholarly journals AB1287-HPR INVESTIGATION OF THE RELATIONSHIP BETWEEN GRIP ENDURANCE, DISABILITY OF UPPER EXTREMITY AND QUALITY OF LIFE IN PATIENTS WITH RHEUMATOID ARTHRITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1933.3-1934
Author(s):  
M. Köprülüoğlu ◽  
İ. Naz Gürşan ◽  
D. Solmaz ◽  
G. Kabadayi ◽  
H. Cinakli ◽  
...  

Background:Upper extremity functions affect the quality of life at different levels in patients with rheumatoid arthritis (RA). In the current literature; it has been shown that grip endurance is associated with upper limb functions (1). However, there is no study investigating the relationship between grip endurance and quality of life in patients with RA.Objectives:To investigate relationship between grip endurance, disability of upper extremity and quality of life in patients with RA.Methods:In our cross sectional study, 23 RA patients [Mean age; 52.7±12.6, BMI;26.9±5.7 kg/m2, Women;20(87.0%)] who were classified according to the ACR 2010 criteria. Demographics and clinical characteristics of patients were recorded (Table 1). Das28 for disease activity score, Static and dynamic grip endurance measurements using Hand Dynamometer (Lafayette Proffessional Hand Dynamometer, USA) for grip endurance, Disability of Arm, Shoulder and Hand Survey (DASH) for disabilities and symptoms of upper extremity and Short Form-36 Health Survey for quality of life were performed. Spearman’s Rank Correlation Coefficient was used for data analysis.Table 1.Demografic and Clinical Characteristics of PatientsVariables (n=23)Median(IQR 25/75)Age (year)56(41/62)BMI (kg/m2)27,5(21.4/32.0)Disease Duration(year)8(5/15)Morning Stiffness (VAS/mm)38(23/48)Perceived Disability of Hand (VAS,mm)47(25/67)Clinician Disability of Hand (VAS,mm)30(20/39)Number Of Tender Hand Joint2(0/6)Number Of Swollen Hand Joint0(0/1)CRP(mg l)3,3(1.8/7.1)ESR(nm/h)13(6/21)n(%)Morning Stiffness Duratton0-15 minutes8 (34.8)15-30 minutes5 (21.7)30-60 minutes3 (13.0)Longer than 1 hours7 (30.4)Das28Remission11(47.8)Low Activity2(8.7)Moderate Activity7(30.4)High Activity3(13.0)Data is presented median (interquantile range) or percentile (%).Results:Grip endurance was negatively correlated with DASH and positively correlated with many different quality of life parameters, especially physical function, on both the dominant and non-dominant sides (p <0.05). DASH was correlated negatively with SF-36 physical function, rol limitataion due to physical health, pain subparameters and positively correlated with Das28 score (p<0.05).Conclusion:In our study, it was concluded that grip endurance was related to upper extremity functions and quality of life in patients with RA. This result shows that; assessment of grip endurance can be a guide for clinicians who have designed an upper limb rehabilitation program for patients with RA.References:1. VERMA, Chhaya, et al. Correlation of functional ability of the hand with upper limb function and quality of life in patients with rheumatoid arthritis.J Assoc Physicians India, 2017, 65: 20-4.Disclosure of Interests:None declared

2016 ◽  
Vol 17 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Sora Park ◽  
Wankyu Eo ◽  
Sookyung Lee

Objectives. This study aimed to identify the relationship between health-related quality of life (HRQoL) measured by the Functional Assessment Cancer Therapy–General (FACT-G) and survival in metastatic colorectal cancer (mCRC) patients. Methods. The clinical characteristics and FACT-G scores were retrospectively reviewed in mCRC patients who visited the Cancer Center of Korean Medicine. The overall survival (OS) was calculated and compared using the Kaplan-Meier method and log-rank test. Univariate and multivariate Cox regression analyses were performed based on clinical characteristics and FACT-G scores. To identify significant differences in answer frequency, χ2 tests and Fisher’s exact tests were used. Results. A total of 58 patients were reviewed. The proportion of patients who had an Eastern Cooperative Oncology Group–Performance Status ≥ 2 was 43.1%, multiple distant metastatic sites was 77.6%, liver metastases was 43.1%, been previously treated was 89.7%, and received more than the second-line chemotherapy was 75.5%. The mean total FACT-G score was 65.3 (median 65.6). The median OS was 7 months. There was no significant difference in OS between the 2 groups divided by the median values of FACT-G total and subscores. In univariate analyses, functional well-being (FWB) score had a significant impact on survival. In multivariate analyses, presence of liver metastasis, FACT-G total score, and FWB score were significant prognostic predictors of survival. No statistically different answer frequency was observed for any question regarding FWB. Conclusions. This study found that FACT-G total and FWB scores were potential prognostic factors for predicting OS in relapsed or refractory mCRC patients treated with Korean Medicine.


2018 ◽  
Vol 12 (3) ◽  
pp. 89-93
Author(s):  
M. A. Makarov ◽  
A. A. Roskidailo ◽  
M. V. Panteleev

Objective:to assess functional results and quality of life in patients with rheumatoid arthritis (RA) after reverse shoulder joint replacement.Patients and methods.Examinations were made in 37 patients with RA involving the shoulder joint, who underwent shoulder joint replacement using a reverse DeltaX-tend DePuy prosthesis in 2006–2017. The investigators studied the volume of movements, the level of pain using the visual analogue scale, the function of the shoulder joint using the American Shoulder and Elbow Surgeons (ASES) Shoulder Score and the upper limb as a whole by the Disability of the Arm, Shoulder and Hand (DASH) questionnaire, a patient's functional status by the Health Assessment Questionnaire (HAQ), quality of life (QL) by EQ-5D (Euro Quolish instrument) and analyzed shoulder X-ray films before and in the late periods after surgery.Results.The volume of shoulder joint movements was found to increase. At 28.7 months postsurgery, the mean volume of flexion, abduction, and external rotation was 107.4Ѓ}15.2, 128.3Ѓ}8.5, and 46.4Ѓ}5.5°; respectively (p≤0.05). The patients experienced no pain in the late periods following surgery. Prior to surgery and at control examination, the mean ASES scores were 25.0Ѓ}4.7 and 79.4Ѓ}6.4, respectively (p≤0.05). Before surgery, the mean DASH score was 63.8Ѓ}4.2; in the late periods it decreased to 18.2Ѓ}8.6 (p ≤ 0.05). The mean preoperative HAQ score was 2.81; following surgery, it also decreased to 1.39 (p≤0.05). The postoperative EQ-5D QOL index score increased from 0.41 to 0.72. The rate of complications reached 10.8%.Conclusion.Reverse endoprosthetic replacement for end-stage shoulder joint damage (Larsen 4–5) with rotator cuff defect makes it possible to increase the volume of movements, to reduce pain, and to improve upper limb function, functional status, and quality of life in patients with RA.


2009 ◽  
Vol 28 (6) ◽  
pp. 685-691 ◽  
Author(s):  
Chia-Ling Chang ◽  
Cheng-Ming Chiu ◽  
Su-Ying Hung ◽  
Si-Huei Lee ◽  
Chang-Shun Lee ◽  
...  

2016 ◽  
Vol 8 (1) ◽  
pp. 159-164 ◽  
Author(s):  
Adebisi I. Hammed ◽  
Elvis I. Agbonlahor

SummaryStudy aim: This study investigated the relationship of clinical characteristics of morbidity (CCM) and marital status with health-related quality of life (HRQoL) among patients with low back pain (LBP).Material and methods: A total of 100 subjects with LBP of mechanical origin participated in this study. HRQoL of the participants was measured with the short form-36 (SF-36) questionnaire and CCM were categorized based on duration of onset of LBP in weeks into acute (<6 weeks), sub-acute (6–12 weeks) and chronic (>12 weeks). The relationship of CCM and marital status with HRQoL was analysed using Pearson’s product moment coefficient of correlation.Results: The outcome of this study showed that CCM correlated poorly and inversely with all domains of HRQoL except mental health, though that was insignificant (p > 0.05). Also, a proportionate but insignificant relationship was found between marital status and domains of HRQoL except physical functioning and role limitations due to physical health problems.Conclusion: It was therefore concluded that CCM and marital status cannot determine or predict HRQoL among LBP patients, and it might not be necessary to take them into consideration during rehabilitation of these individuals.


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