Complex regional pain syndrome following immunisation

Complex regional pain syndrome type 1 (CRPS-1) is a clinical syndrome that affects one or more extremities and is characterised by persistent pain disproportionate to any inciting event, and at least one sign of autonomic dysfunction in the affected limb(s). The pathogenesis of this syndrome is poorly understood, but its onset is often precipitated by a physical injury, such as minor trauma, fracture, infection or a surgical procedure. In the literature, there are reports of CRPS-1 following immunisation with rubella and hepatitis B vaccines. Here we present a case series of CRPS-1 following immunisation in adolescents, with either diphtheria-tetanus-acellular pertussis (1 case), or human papillomavirus vaccines (4 cases). Enhanced awareness of this syndrome and its potential to occur following immunisation in the paediatric population is vital to the prompt and effective management of this condition.

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Changes in regional cerebral blood flow in the thalamus after electroconvulsive therapy for patients with complex regional pain syndrome type 1 (preliminary case series)

Regional Anesthesia and Pain Medicine ◽

10.1053/rapm.2002.34330 ◽

2002 ◽

Vol 27 (5) ◽

pp. 529-532 ◽

Cited By ~ 1

Author(s):

S FUKUI ◽

S SHIGEMORI ◽

S NOSAKA

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Complex Regional Pain Syndrome ◽

Electroconvulsive Therapy ◽

Regional Cerebral Blood Flow ◽

Case Series ◽

Pain Syndrome ◽

Syndrome Type ◽

Regional Cerebral Blood

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Changes in Regional Cerebral Blood Flow in the Thalamus After Electroconvulsive Therapy for Patients with Complex Regional Pain Syndrome Type 1 (Preliminary Case Series)

Regional Anesthesia and Pain Medicine ◽

10.1097/00115550-200209000-00018 ◽

2002 ◽

Vol 27 (5) ◽

pp. 529-532 ◽

Cited By ~ 14

Author(s):

Sei Fukui ◽

Shino Shigemori ◽

Shuichi Nosaka

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Complex Regional Pain Syndrome ◽

Electroconvulsive Therapy ◽

Regional Cerebral Blood Flow ◽

Case Series ◽

Pain Syndrome ◽

Syndrome Type ◽

Regional Cerebral Blood

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Fracture of the Wrist and Incidence of the Complex Regional Pain Syndrome Type 1: A Case Series Study

Journal of Orthopedic and Spine Trauma ◽

10.18502/jost.v4i4.3098 ◽

2020 ◽

Author(s):

Payam Vezvaei ◽

Soroosh Alizadeh ◽

Saeed Reza Mehrpour ◽

Leila Oryadi-Zanjani

Keyword(s):

Distal Radius Fracture ◽

Complex Regional Pain Syndrome ◽

Distal Radius ◽

Case Series ◽

Pain Syndrome ◽

Radius Fracture ◽

Case Series Study ◽

Budapest Criteria ◽

Series Study

Background: Complex regional pain syndrome (CRPS) is a painful syndrome with signs such as swelling, restriction of motion, and discoloration of the skin and bone. CRPS is divided into two types based on neurological injuries. Type 1 CRPS (CRPS-I), which is more common, has no nerve damage. In this study, we used the Budapest Criteria to investigate the incidence of CRPS. We also evaluated the risk factors for the incidence of CRPS. Methods: This single-center case series study was performed at Shariati Hospital of Tehran University of Medical Sciences, Tehran, Iran, during 2018-2019. We evaluated CRPS-I, two and six weeks after treatment based on Budapest Criteria. The inclusion criteria included distal radius fracture confirmed by clinical and radiographic investigations. The exclusion criteria were patients with fractures in another part of the body, associated nerve damage, vascular injury, and an open fracture. Results: Sixty-two patients with distal radius fracture who underwent casting or surgical treatment enrolled in the study. A total of 9 (14.5%) patients had CRPS-I after distal radius fracture. In 5 (8.1%) patients, CRPS-I occurred within two weeks after fracture. Also, 4 (6.5%) patients had CRPS-I after six weeks from fracture. There was no significant difference between the two sex groups in terms of CRPS (P = 0.345). This complication was significantly higher in the surgical group than in the casting group (P = 0.004). Conclusions: Given the significant incidence of CRPS and its impact on patient's quality of life, further studies are recommended to explore solutions to reduce this complication.

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V01 Poster location 001 Fixed dystonia in complex regional pain syndrome Type 1 responds to deep brain stimulation (DBS) – a case series of 2 patients

European Journal of Paediatric Neurology ◽

10.1016/s1090-3798(09)70021-2 ◽

2009 ◽

Vol 13 ◽

pp. S6-S7

Author(s):

S.S. Gill ◽

S. Javed ◽

S. Khan ◽

P. Sharples ◽

A. Majumdar ◽

...

Keyword(s):

Deep Brain Stimulation ◽

Complex Regional Pain Syndrome ◽

Brain Stimulation ◽

Case Series ◽

Pain Syndrome ◽

Syndrome Type ◽

Fixed Dystonia ◽

Deep Brain

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Complex Regional Pain Syndrome in Athletes: Scoping Review

Medicina ◽

10.3390/medicina57111262 ◽

2021 ◽

Vol 57 (11) ◽

pp. 1262

Author(s):

Antimo Moretti ◽

Angela Palomba ◽

Marco Paoletta ◽

Sara Liguori ◽

Giuseppe Toro ◽

...

Keyword(s):

Complex Regional Pain Syndrome ◽

Case Reports ◽

Management Strategies ◽

Case Series ◽

Pain Syndrome ◽

Assessment Tools ◽

Lower Limbs ◽

Online Databases ◽

High Prevalence

Background and Objectives: Complex regional pain syndrome (CRPS) is a chronic condition characterized by disproportionate regional pain, usually affecting distal limbs, that follows trauma or surgery. Athletes may develop CRPS because of exposure to traumatic or overuse injuries. The aim of the present study is to review the available literature about CRPS type 1 in athletes. Materials and Methods: We searched two online databases (PubMed and Web of Science), selecting papers aiming at investigating CRPS type 1 (algodystrophy) in athletes. The analysis of databases was made considering original articles published until 30 June 2021, written in English. Results: Fifteen papers (12 case reports, 3 case series) were selected for a total of 20 clinical cases (15 females, 5 males), aged between 10 and 46 years (mean age 18.4 ± 9.8 standard deviation years). Patients included practiced different types of sport (soccer, athletics, gymnastics, basketball). The most involved anatomical sites were lower limbs, and time to diagnosis ranged from 2 days to 4 years. The most used treatments were pharmacological and physical therapies, but sometimes invasive approaches, as regional nerve, or lumbar sympathetic blocks, were provided. The main assessed outcomes were return to activity and pain. Conclusions: Our review suggests a higher prevalence of CRPS type 1 in younger people and in lower limbs than in general population but confirms the higher prevalence in females. However, the number of studies addressing CRPS in athletes is limited, as well as the number of involved patients, considering that only few and heterogeneous case reports were published about this topic. Moreover, the high prevalence of old studies (only 5 available studies in the last 10 years) might have influenced the choice of both assessment tools and management strategies. Despite these limitations, athletes showing disproportionate pain after sport-related injury should be promptly evaluated and treated through a multidimensional approach to avoid long-term consequences of algodystrophy.

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Pain exposure physical therapy may be a safe and effective treatment for longstanding complex regional pain syndrome type 1: a case series

Clinical Rehabilitation ◽

10.1177/0269215509339875 ◽

2009 ◽

Vol 23 (12) ◽

pp. 1059-1066 ◽

Cited By ~ 38

Author(s):

Jan-Willem Ek ◽

Jan C van Gijn ◽

Han Samwel ◽

Jan van Egmond ◽

Frank PAJ Klomp ◽

...

Keyword(s):

Physical Therapy ◽

Effective Treatment ◽

Complex Regional Pain Syndrome ◽

Case Series ◽

Pain Syndrome ◽

Syndrome Type

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Challenges in the Diagnostic Conceptualization of CRPS-1 (Formerly Conceptualized as RSD)

Guides Newsletter ◽

10.1001/amaguidesnewsletters.2006.marapr01 ◽

2006 ◽

Vol 11 (2) ◽

pp. 1-3, 9-12

Author(s):

Robert J. Barth ◽

Tom W. Bohr

Keyword(s):

Clinical Practice ◽

Complex Regional Pain Syndrome ◽

Somatoform Disorders ◽

International Association ◽

Pain Syndrome ◽

Somatoform Disorder ◽

Syndrome Type ◽

Previous Issue

Abstract From the previous issue, this article continues a discussion of the potentially confusing aspects of the diagnostic formulation for complex regional pain syndrome type 1 (CRPS-1) proposed by the International Association for the Study of Pain (IASP), the relevance of these issues for a proposed future protocol, and recommendations for clinical practice. IASP is working to resolve the contradictions in its approach to CRPS-1 diagnosis, but it continues to include the following criterion: “[c]ontinuing pain, which is disproportionate to any inciting event.” This language only perpetuates existing issues with current definitions, specifically the overlap between the IASP criteria for CRPS-1 and somatoform disorders, overlap with the guidelines for malingering, and self-contradiction with respect to the suggestion of injury-relatedness. The authors propose to overcome the last of these by revising the criterion: “[c]omplaints of pain in the absence of any identifiable injury that could credibly account for the complaints.” Similarly, the overlap with somatoform disorders could be reworded: “The possibility of a somatoform disorder has been thoroughly assessed, with the results of that assessment failing to produce any consistencies with a somatoform scenario.” The overlap with malingering could be addressed in this manner: “The possibility of malingering has been thoroughly assessed, with the results of that assessment failing to produce any consistencies with a malingering scenario.” The article concludes with six recommendations, and a sidebar discusses rating impairment for CRPS-1 (with explicit instructions not to use the pain chapter for this purpose).

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