Priorities for child health research across the UK and Ireland

2021 ◽  
pp. archdischild-2021-322636
Author(s):  
Katrina Cathie ◽  
Alastair G Sutcliffe ◽  
Srini Bandi ◽  
David Coghlan ◽  
Stephen W Turner ◽  
...  
Keyword(s):  
Child Health ◽  
Research Priorities ◽  
Models Of Care ◽  
Research Network ◽  
Second Phase ◽  
Modified Delphi ◽  
Phase Study ◽  
Child Health Research ◽  
The Uk ◽  
Multicentre Research

BackgroundThe General and Adolescent Paediatric Research Network in the UK and Ireland (GAPRUKI) was established in 2016. The aims of GAPRUKI are to unite general paediatricians around the UK and Ireland, to develop research ideas and protocols, and facilitate delivery of multicentre research.ObjectivesTo undertake a research prioritisation exercise among UK and Ireland general paediatricians.MethodsThis was a four-phase study using a modified Delphi survey. The first phase asked for suggested research priorities. The second phase developed ideas and ranked them in priority. In the third phase, priorities were refined; and the final stage used the Hanlon Prioritisation Process to agree on the highest priorities.ResultsIn phase one, there were 250 questions submitted by 61 GAPRUKI members (66% of the whole membership). For phase two, 92 priorities were scored by 62 members and the mean Likert scale (1–7) scores ranged from 3.13 to 5.77. In a face-to-face meeting (phases three and four), 17 research questions were identified and ultimately 14 priorities were identified and ranked. The four priorities with the highest ranking focused on these three respiratory conditions: asthma, bronchiolitis and acute wheeze. Other priorities were in the diagnosis or management of constipation, urinary tract infection, fever, gastro-oesophageal reflux and also new models of care for scheduled general paediatric clinics.ConclusionResearch priorities for child health in the UK and Ireland have been identified using a robust methodology. The next steps are for studies to be designed and funded to address these priorities.

scholarly journals Forming a Parent And Clinician Team (PACT) in a cohort of healthy children

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Shelley M. Vanderhout ◽  
Catherine S. Birken ◽  
Maria Zaccaria Cho ◽  
Jonathon L. Maguire
Keyword(s):  
Health Care ◽  
Child Health ◽  
Health Research ◽  
Design Research ◽  
Research Priorities ◽  
Research Network ◽  
Main Body ◽  
Healthy Children ◽  
Study Results ◽  
Child Health Research

Abstract Background Engaging parents in child health research can facilitate choosing relevant research questions, recruiting participants who reflect the diversity of large communities, and disseminating study results to communities in accessible ways. Main body Primary care well-child visit systems present a foundation for trusting relationships between families and clinicians, lending itself well to a system where health research is embedded into the delivery of health care. We provide an example of a practice-based research network called TARGet Kids!, which is a longitudinal cohort study of children from birth to adolescence. Researchers and clinicians have partnered with parents of children participating in TARGet Kids! to ensure child health research is centred on family values and preferences. A Parent And Clinician Team (PACT) was formed to set research priorities, co-design research protocols, troubleshoot issues, and communicate research to knowledge users. Conclusion This partnership will facilitate child health research which is feasible, relevant and inclusive for improving children’s health care and public health policy.

A healthy nation: strengthening child health research in the UK

The Lancet ◽  
2013 ◽  
Vol 381 (9860) ◽  
pp. 73-87 ◽  
Author(s):  
Neena Modi ◽  
Howard Clark ◽  
Ingrid Wolfe ◽  
Anthony Costello ◽  
Helen Budge
Keyword(s):  
Child Health ◽  
Health Research ◽  
Child Health Research ◽  
The Uk

scholarly journals P.010 The Canadian Neurosurgery Research Collaborative (CNRC): A novel, trainee-led, nationwide multicentre research network

2016 ◽  
Vol 43 (S2) ◽  
pp. S23-S24 ◽  
Author(s):  
A Dakson ◽  
M Bigder ◽  
C Elliott ◽  
D Guha ◽  
C Iorio-Morin ◽  
...  
Keyword(s):  
Potential Role ◽  
Research Network ◽  
Study Quality ◽  
Research Culture ◽  
The United Kingdom ◽  
Potential Benefits ◽  
Multicenter Prospective Study ◽  
Objective Basis ◽  
The Uk ◽  
Multicentre Research

Background: The goals of evidence-based neurosurgery are to improve surgical outcomes, reduce complications, and provide an objective basis for altering practice. The need for higher quality studies, typically prospective and multicentre, has been growing especially in light of the evolving complexity of neurosurgical interventions and heterogeneity of patient populations. In the United Kingdom (UK), trainee-led research collaboratives have been established to tackle this problem. Therefore, we sought to evaluate the potential role for a resident-led research collaborative in neurosurgery in Canada based on the UK experience. Methods: A literature review of trainee-led collaboratives was conducted utilizing PubMed and Medline. Identified articles were reviewed for study quality and clinical relevance to explore the potential benefits of collaboratives. Results: In the UK, 27 collaboratives have been established in various specialties by trainees. Some published high quality trials with implications on their clinical fields. Evidence suggests that such endeavors improves trainees’ research skills and may help cultivate a research culture tailored towards clinical trials. Conclusions: Given the growing evidence for research collaboratives in the UK, we propose launching the Canadian Neurosurgery Research Collaborative (CNRC) which currently represents 12 out of 14 neurosurgery programs in Canada, and planning its first multicenter prospective study.

scholarly journals Identifying the research priorities of healthcare professionals in UK vascular surgery: modified Delphi approach

BJS Open ◽  
2020 ◽  
Vol 5 (2) ◽  
Author(s):  
G E Smith ◽  
J Long ◽  
T Wallace ◽  
D Carradice ◽  
I C Chetter ◽  
...  
Keyword(s):  
Unmet Need ◽  
Research Priorities ◽  
Plaque Morphology ◽  
Limb Ischaemia ◽  
Modified Delphi ◽  
Delphi Approach ◽  
Steering Group ◽  
Surgical Trainees ◽  
Foot Disease ◽  
The Uk

Abstract Background The Vascular Research Collaborative was established to develop a national research strategy for patients with vascular disease in the UK. This project aimed to establish national research priorities in this patient group. Methods A modified Delphi approach, an established method for reaching a consensus opinion among a group of experts in a particular field, was used to survey national multidisciplinary vascular clinical specialists. Two rounds of online surveys were conducted involving the membership of the Vascular Society, Society of Vascular Nurses, Society for Vascular Technology, and the Rouleaux Club (vascular surgical trainees). The first round invited any suggestions for vascular research topics. A steering group then collated and rationalized the suggestions, categorizing them by consensus into pathological topics and research categories, and amalgamating the various questions relating to the same fundamental issue into a single question. The second round involved recirculating these questions to the same participants for priority scoring. Results Round 1 resulted in 1231 suggested research questions from 481 respondents. Steering group collation and rationalization resulted in 83 questions for ranking in round 2. The second round resulted in a hierarchical list of vascular research priorities. The highest scoring priorities addressed topics related to critical lower-limb ischaemia, diabetic foot disease, amputation, wound healing, carotid plaque morphology, and service organization/delivery. Conclusion It is anticipated that these results will drive the UK national vascular research agenda for the next 5–10 years. It will facilitate focused development and funding of new research projects in current clinical areas of unmet need where potential impact is greatest.

scholarly journals Current research priorities for UK occupational physicians and occupational health researchers: a modified Delphi study

2018 ◽  
Vol 75 (11) ◽  
pp. 830-836 ◽  
Author(s):  
Drushca Lalloo ◽  
Evangelia Demou ◽  
Julia Smedley ◽  
Ira Madan ◽  
Kaveh Asanati ◽  
...  
Keyword(s):  
Occupational Health ◽  
Delphi Study ◽  
Research Priorities ◽  
Research Strategy ◽  
Occupational Physicians ◽  
Modified Delphi ◽  
Modified Delphi Technique ◽  
The Uk ◽  
Almost All ◽  
Effectiveness Studies

ObjectivesStudies identifying national occupational health (OH) research priorities have been conducted in several countries to establish where OH research should be focused and where funding should be targeted. However, the UK findings are now over 20 years old, and OH practice is continuously evolving. The aim of this study was to identify current research priorities for UK occupational physicians (OPs) and occupational health researchers (OHRs).MethodsCurrent research priorities in OH were identified using a modified Delphi technique. This was conducted in two rounds to achieve consensus. Research priorities were rated, and then ranked using questionnaires developed from expert panel discussions, key research topics identified from the medical literature and participant feedback. Overall and intergroup comparisons were completed for the ranking scores.ResultsConsensus among OPs and OHRs was high with almost all (9/10) primary domains rated as ‘very important’ or ‘absolutely necessary’ by more than 54% of respondents. The research priority areas ranked highest were jointly economic evaluation/cost effectiveness studies and disability management followed by occupational disease/injury/illness. Occupational health policy was ranked lowest after sickness absence management and health promotion. The secondary domain analysis identified priority emphasis on mental health and psychosocial hazards within the workplace and the need to further develop evidence-based guidance for clinical OH practice.ConclusionsWe identified the current research priorities for UK OPs and OHRs. The findings will inform future national OH research strategy and support research that addresses important knowledge gaps within OH and other interdisciplinary specialties.

scholarly journals Three-Dimensional Analysis of the In Vivo Motion of Implantable Cardioverter Defibrillator Leads

2021 ◽  
Author(s):  
Tamas Szili-Torok ◽  
Jens Rump ◽  
Torsten Luther ◽  
Sing-Chien Yap
Keyword(s):  
Three Dimensional ◽  
Second Phase ◽  
Two Phase ◽  
Maximum Curvature ◽  
Phase Study ◽  
Absolute Curvature ◽  
Icd Leads ◽  
Lead Testing ◽  
Design And Testing

Abstract Better understanding of the lead curvature, movement and their spatial distribution may be beneficial in developing lead testing methods, guiding implantations and improving life expectancy of implanted leads. Objective The aim of this two-phase study was to develop and test a novel biplane cine-fluoroscopy-based method to evaluate input parameters for bending stress in leads based on their in vivo 3D motion using precisely determined spatial distributions of lead curvatures. Potential tensile, compressive or torque forces were not subjects of this study. Methods A method to measure lead curvature and curvature evolution was initially tested in a phantom study. In the second phase using this model 51 patients with implanted ICD leads were included. A biplane cine-fluoroscopy recording of the intracardiac region of the lead was performed. The lead centerline and its motion were reconstructed in 3D and used to define lead curvature and curvature changes. The maximum absolute curvature Cmax during a cardiac cycle, the maximum curvature amplitude Camp and the maximum curvature Cmax@amp at the location of Camp were calculated. These parameters can be used to characterize fatigue stress in a lead under cyclical bending. Results The medians of Camp and Cmax@amp were 0.18 cm−1 and 0.42 cm−1, respectively. The median location of Cmax was in the atrium whereas the median location of Camp occurred close to where the transit through the tricuspid valve can be assumed. Increased curvatures were found for higher slack grades. Conclusion Our results suggest that reconstruction of 3D ICD lead motion is feasible using biplane cine-fluoroscopy. Lead curvatures can be computed with high accuracy and the results can be implemented to improve lead design and testing.

Sign in / Sign up

Export Citation Format

Share Document