Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy.

Abstract Background: IAP （intra-articular pressure）of the knee has been extensively studied in the knee of rheumatoid arthritis1.3 . the relationship between IAP and osteoarthrosis of knee rarely mentioned in the literature. The purpose of the study was to discover the pressure profiles observed in OA(Osteoarthritis ）. The characteristics of osteoarthritis are multiple osteophytes, unstable chondral flaps ,joint-space narrowing，sclerosis. Whether these factors effect of osteoarthritis intra-articular pressure.Methods: Fifty three research subjects were studied. They were divided into two subgroups, group 1: Forty osteoarthritis (OA). group 2: Thirteen control knee of healthy volunteer. IAP was measured using the hand held portable water manometer. before operation of arthroscopic procedures in OAgroup . Research data were analyzed to identify IAP between the two groups. Results: The main findingwasthat Resting IAP was positive pressure in all Osteoarthritis joints, otherwise subatmospheric or weakly atmospheric in normal subjects. Conclusions: The IAP rising is a feature of all patients with OAgroup. Therefore, These observations we recognize that significantly increased resting IAP is major influences by multiple osteophytes, joint-space narrowing，sclerosis , loose bodies and definite deformity of bony ends.

Download Full-text

Relationship between arthroscopic evidence of cartilage damage and radiographic evidence of joint space narrowing in early osteoarthritis of the knee

Arthritis & Rheumatism ◽

10.1002/art.1780340402 ◽

1991 ◽

Vol 34 (4) ◽

pp. 377-382 ◽

Cited By ~ 152

Author(s):

Rose S. Fife ◽

Kenneth D. Brandt ◽

Ethan M. Braunstein ◽

Barry P. Katz ◽

K. Donald Shelbourne ◽

...

Keyword(s):

Joint Space Narrowing ◽

Cartilage Damage ◽

Joint Space ◽

Osteoarthritis Of The Knee ◽

Early Osteoarthritis ◽

Radiographic Evidence

Download Full-text

Speed of the joint space narrowing (JSN) in primary medial osteoarthritis of the knee (OAK) over 3–5 years

Osteoarthritis and Cartilage ◽

10.1016/s1063-4584(05)80162-1 ◽

1993 ◽

Vol 1 (1) ◽

pp. 23-23 ◽

Cited By ~ 2

Keyword(s):

Joint Space Narrowing ◽

Joint Space ◽

Osteoarthritis Of The Knee ◽

Medial Osteoarthritis

Download Full-text

Association between radiographic joint space narrowing, function, pain and muscle power in severe osteoarthritis of the knee

Clinical Rehabilitation ◽

10.1191/0269215504cr754oa ◽

2004 ◽

Vol 18 (7) ◽

pp. 793-800 ◽

Cited By ~ 84

Author(s):

Karen Barker ◽

Sarah E Lamb ◽

Francine Toye ◽

Sarah Jackson ◽

Sharon Barrington

Keyword(s):

Joint Space Narrowing ◽

Muscle Power ◽

Joint Space ◽

Osteoarthritis Of The Knee

Download Full-text

Progressive increase in body mass index is not associated with a progressive increase in joint space narrowing in obese women with osteoarthritis of the knee

Annals of the Rheumatic Diseases ◽

10.1136/ard.2007.085530 ◽

2008 ◽

Vol 68 (11) ◽

pp. 1734-1738 ◽

Cited By ~ 13

Author(s):

M-P H. Le Graverand ◽

K Brandt ◽

S A Mazzuca ◽

D Raunig ◽

E Vignon

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Joint Space Narrowing ◽

Joint Space ◽

Progressive Increase ◽

Osteoarthritis Of The Knee ◽

Obese Women

Download Full-text

Varus alignment of the proximal tibia is associated with structural progression in early to moderate varus osteoarthritis of the knee

Knee Surgery Sports Traumatology Arthroscopy ◽

10.1007/s00167-019-05840-5 ◽

2020 ◽

Vol 28 (10) ◽

pp. 3279-3286 ◽

Cited By ~ 3

Author(s):

Jonathan S. Palmer ◽

Luke D. Jones ◽

A. Paul Monk ◽

Michael Nevitt ◽

John Lynch ◽

...

Keyword(s):

Cohort Study ◽

Lower Limb ◽

Joint Space Narrowing ◽

Proximal Tibia ◽

Joint Space ◽

Medial Compartment ◽

Osteoarthritis Of The Knee ◽

Varus Alignment ◽

Medial Proximal Tibial Angle ◽

Structural Progression

Abstract Purpose Lower limb malalignment is a strong predictor of progression in knee osteoarthritis. The purpose of this study is to identify the individual alignment variables that predict progression in early to moderate osteoarthritis of the knee. Method A longitudinal cohort study using data from the Osteoarthritis Initiative. In total, 955 individuals (1329 knees) with early to moderate osteoarthritis (Kellgren-Lawrence grade 1, 2 or 3) were identified. All subjects had full-limb radiographs analysed using the Osteotomy module within Medicad® Classic (Hectec GMBH) to give a series of individual alignment variables relevant to the coronal alignment of the lower limb. Logistic regression models, with generalised estimating equations were used to identify which of these individual alignment variables predict symptom worsening (WOMAC score > 9 points) and or structural progression (joint space narrowing progression in the medial compartment > 0.7mm) over 24 months. Results Individual alignment variable were associated with both valgus and varus alignment (mechanical Lateral Distal Femoral Angle, Medial Proximal Tibial Angle and mechanical Lateral Distal Tibial Angle). Only the Medial Proximal Tibial Angle was significantly associated with structural progression and none of the variables was associated with symptom progression. The odds of joint space narrowing progression in the medial compartment occurring at 24 months increased by 21% for every one degree decrease (more varus) in Medial Proximal Tibial Angle (p < 0.001) Conclusions Our results suggest that the risk of structural progression in the medial compartment is associated with greater varus alignment of the proximal tibia. Level of evidence Level III, retrospective cohort study.

Download Full-text