scholarly journals Thoracic high resolution computed tomography in patients with ankylosing spondylitis and without respiratory symptoms

2003 ◽  
Vol 62 (2) ◽  
pp. 185-186 ◽  
Author(s):  
A El Maghraoui
Author(s):  
Nazeem Fathima ◽  
Balamma Sujatha ◽  
Shami RP Kumar ◽  
S Rajesh

Concurrent bacteremia in patients with dengue fever is rarely reported. Two and a half-year-old female child with fever, cough and cold for six days presented to Emergency Room (ER) with tachypnea, tachycardia and hepatomegaly. Investigations revealed dengue fever. Respiratory symptoms probed us to investigate the case further. High-Resolution Computed Tomography (HRCT) thorax showed moderate pleural effusion with collapse consolidation of left lung and a thin walled cavity with septations and fluid in left upper lobe. Child was treated with injection meropenem and vancomycin successfully.


2004 ◽  
Vol 24 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Remzi Altin ◽  
Şenay Özdolap ◽  
Ahmet Savranlar ◽  
Selda Sarıkaya ◽  
Meltem Tor ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
A. Majjad ◽  
A. Bezza ◽  
A. Biyi ◽  
M. R. El Ochi ◽  
A. El Maghraoui

Antitumor necrosis factor therapies have revolutionized the treatment of some inflammatory diseases. However, the use of these agents is associated with the development of many paradoxical autoimmune diseases. Less well-recognized is the association with sarcoidosis. We report a 55-year-old female with long-standing ankylosing spondylitis who developed persistent dry cough and dyspnea while receiving etanercept therapy. High-resolution computed tomography scanning showed mediastinal lymphadenopathy and multiple nodules in both lung fields developed two months after the administration of etanercept. Lymph node biopsy was not practicable. Histopathological examination of minor salivary gland biopsy revealed noncaseating granulomata, and the serum angiotensin-converting enzyme was very elevated. All infectious studies were negative. Etanercept was discontinued plus a course of corticosteroids with a clinical improvement, and a follow-up high-resolution computed tomography scanning 4 months later showed evident regression of mediastinal lymph nodes and pulmonary nodules. Potential pathogenic mechanisms of this paradoxical effect of tumor necrosis factor-alpha blocking agents are discussed.


2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Shu Hisata ◽  
Yuichiro Kimura ◽  
Naoko Shibata ◽  
Shuichi Ono ◽  
Takao Kobayashi ◽  
...  

Both SP-D and KL-6/MUC1 are established biomarkers of the interstitial pneumonias, including idiopathic pulmonary fibrosis (IPF), but the causes and clinical outcomes based on their independent effects are not known. Eleven asymptomatic patients, detected with honeycombing on high-resolution computed tomography (HRCT), were compared with 17 other IPF outpatients having slight respiratory symptoms and honeycombing as well. Although SP-D was increased in both groups, KL-6 was significantly higher in the symptomatic IPF group. When the patients (n=11) having both biomarkers elevated were compared with the other patients (n=6) with only SP-D elevated, the distribution of fibrotic lesions with honeycombing on HRCT was larger and the survival time was shorter in the patients having both biomarkers elevated. Immunohistochemical analysis also differentiated these biomarkers in the lung. These results suggest both a cause and the prognostic value of dissociation of these biomarkers.


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