Case of cholestatic jaundice associated with papillary carcinoma of thyroid: a multidisciplinary challenge

2021 ◽  
Vol 14 (2) ◽  
pp. e236372 ◽  
Author(s):  
Sanchit Sharma ◽  
Anoop Saraya ◽  
Prasenjit Das ◽  
Deepak Gunjan
Keyword(s):  
Papillary Carcinoma ◽  
Primary Tumour ◽  
Symptomatic Treatment ◽  
Liver Function Tests ◽  
Needle Aspiration ◽  
Cholestatic Jaundice ◽  
Drug Induced ◽  
Post Surgery ◽  
Positron Emission ◽  
Needle Aspiration Cytology

The report describes a patient with cholestatic jaundice who had incidentally detected parathyroid hormone-independent hypercalcaemia. The differential diagnosis for this presentation includes systemic granulomatous and infiltrative disorders, drug-induced liver injury and malignancy. As the initial investigations were non-contributory towards the aetiology, she was given steroids and later plasma exchange for symptomatic treatment. The differentials were revised again in view of no clinical and biochemical response. A repeat fine-needle aspiration cytology of the thyroid nodule (seen on positron emission tomography/CT) revealed papillary carcinoma of the thyroid. The patient underwent total thyroidectomy. There was a complete normalisation of liver function tests and serum calcium, and resolution of pruritus 3 months post surgery. She was retrospectively diagnosed as a case of papillary carcinoma of the thyroid with paraneoplastic manifestations—hypercalcaemia and cholestatic jaundice—which got resolved with treatment of the primary tumour.

scholarly journals A prospective clinico-pathological study of cervical lymphadenopathy

2017 ◽  
Vol 4 (12) ◽  
pp. 3967
Author(s):  
Narender N. R. ◽  
Yadagiri Rao J.
Keyword(s):  
Lymph Nodes ◽  
Prospective Observational Study ◽  
Primary Tumour ◽  
Cervical Lymphadenopathy ◽  
Needle Aspiration ◽  
Excision Biopsy ◽  
Medical Sciences ◽  
Aspiration Cytology ◽  
Needle Aspiration Cytology ◽  
Carcinoma Tongue

Background: Lymphadenopathy refers to one or more lymph nodes that are abnormal in size, consistency or number. There are various causes for lymphadenopathy which range from benign conditions to malignant either primary or secondary from draining primary tumour. Lymphadenopathy can be localised to a single group or generalised.Methods: Prospective observational study was performed for the patients attending outpatient department of general surgery at Kamineni academy of medical sciences, LB nagar Hyderabad, Telangana with complaints of enlarged or swollen lymph nodes in the neck. This study included 46 cases. In cases where fine needle aspiration cytology was inconclusive and there was need for excision biopsy, only these cases were included in the study. After biopsy lymph node was sent for gross and microscopic examination for expert opinion from department of pathology.Results: The present study includes 46 patients in a period of two years from 01-8-2015 to 31-7-2017. Of these case tuberculosis lymphadenopathy (n=25,54.3%) was the most common aetiology followed by nonspecific chronic lymphadenopathy (n=16,34.7%) followed by some relatively rare cases and unusual presentation Schwannoma, pleomorphic adenoma, Kikuchi disease, non-Hodgkin’s lymphoma and secondaries from carcinoma tongue (n=1,2.1%).Conclusions: In the present prospective study tubercular lymphadenopathy was the most common cause for cervical lymphadenopathy followed by chronic nonspecific lymphadenopathy. 

scholarly journals Primary retroperitoneal mullerian adenocarcinoma

Rare Tumors ◽  
2010 ◽  
Vol 2 (1) ◽  
pp. 16-19 ◽  
Author(s):  
Ayman Elnemr ◽  
Yutaka Yonemura ◽  
Masaya Shinbo ◽  
Eisei Nishino
Keyword(s):  
Abdominal Mass ◽  
Needle Aspiration ◽  
Cystic Mass ◽  
High Serum ◽  
Aspiration Cytology ◽  
Positron Emission ◽  
Pet Scanning ◽  
History Of ◽  
Needle Aspiration Cytology ◽  
Primary Retroperitoneal

Mullerian tumors are extremely rare malignancies in the retroperitoneum. We report a case of a 46-year old woman who presented with an eight year history of lower abdominal mass. Ultrasonography (US) and computed tomography (CT) demonstrated a 15×10 cm cystic mass in the left lower retroperitoneum. As serial percutaneous needle aspiration cytology was negative for malignancy, she was observed for seven years. Eleven months ago, the mass was excised. The histopathology was reported as mucinous adenocarcinoma of the retroperitoneum. Six cycles of intraperitoneal (IP) chemotherapy was administered during the last six months after diagnosis of recurrence by aspiration cytology and high serum tumor markers (CEA, CA19-9). A few days ago, positron emission tomographic (PET) scanning showed evidence of local recurrence and single vertebral metastasis, so she was admitted again for systemic chemotherapy. Meticulous revision of additional sections of the tumor revealed papillary, serous, mucinous, and endometrioid subtypes of the mullerian adenocarcinoma. To our knowledge, there has been no similar case described in the literature.

Pitfalls and Key Features of a Case of Sclerosing Pneumocytoma: A Cytological Challenge?

2016 ◽  
Vol 60 (1) ◽  
pp. 85-88 ◽  
Author(s):  
Monica Onorati ◽  
Marta Nicola ◽  
Chiara Luisa Bianchi ◽  
Francesco Bini ◽  
Nadia Bellaviti ◽  
...  
Keyword(s):  
Lung Nodule ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Lung Tumour ◽  
Current Case ◽  
Sclerosing Hemangioma ◽  
Positron Emission ◽  
Key Features ◽  
Needle Aspiration Cytology ◽  
Tomography Scan

Background: The aim of the current case report is to re-evaluate the key features and pitfalls of fine-needle aspiration cytology (FNAC) in the diagnosis of sclerosing pneumocytoma (previously named sclerosing hemangioma) and to establish the importance of FNAC in addressing a proper surgical strategy. Case: Herein we documented a case of a 70- year-old man with a lung nodule which showed a hypermetabolic uptake on positron emission tomography. He therefore underwent FNAC under computed tomography scan guidance with a 22-gauge needle. The cytopathological examination allowed a diagnosis of sclerosing pneumocytoma. A wedge surgical excision was performed and the histological examination confirmed the cytological diagnosis. Conclusion: FNAC is a fundamental tool for distinguishing sclerosing pneumocytoma from a malignant lung tumour and together with clinical, radiological and pathological multidisciplinary assessment is indispensable in planning appropriate surgical management. Cytopathologists should be aware of the pitfalls and key features of the cytopathological diagnosis of sclerosing pneumocytoma, which can significantly change the surgical approach to the patient and protect him from aggressive overtreatment.

Fine Needle Aspiration Cytology of the Oxyphil Variant of Papillary Carcinoma of the Thyroid

1996 ◽  
Vol 40 (5) ◽  
pp. 1007-1011 ◽  
Author(s):  
Manuel I. Doria, Jr. ◽  
Houssam Attal ◽  
Helena H. Wang ◽  
Jo Anne Jensen ◽  
Richard M. DeMay
Keyword(s):  
Papillary Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Rare case of metastatic small cell carcinoma of the nasopharynx to the pancreas

2020 ◽  
Vol 13 (6) ◽  
pp. e235054 ◽  
Author(s):  
Jonathan Teinor ◽  
Lara Groshek ◽  
Jin He
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Primary Tumour ◽  
Treatment Options ◽  
Needle Aspiration ◽  
Concurrent Chemotherapy ◽  
Small Cell ◽  
Tissue Mass ◽  
Positron Emission ◽  
History Of

We present a 49-year-old woman with a history of an unresectable nasopharyngeal small cell carcinoma (SCC) who was treated with concurrent chemotherapy and radiation therapy. On surveillance positron emission tomography scan 14 months after diagnosis, her primary tumour appeared stable, but there was fludeoxyglucose uptake in the pancreas. A CT scan demonstrated a 3.4×2.1 cm ill-defined soft tissue mass at the tail of the pancreas, which was concerning for adenocarcinoma. However, further workup including endoscopic ultrasound and fine needle aspiration confirmed the mass to be a metastasis from her nasopharyngeal SCC. Because there have been no previously reported cases of a metastatic small cell carcinoma to the pancreas, there are no data about prognosis. Thus treatment options were tailored to the patient. Distal pancreatectomy, splenectomy and cholecystectomy were performed. The patient recovered from surgery without complication.

Sign in / Sign up

Export Citation Format

Share Document