Unusual presentation of sarcoidosis, requiring a positron emission tomography/CT (PET/CT) for diagnosis

2021 ◽  
Vol 14 (1) ◽  
pp. e237424
Author(s):  
Kenneth O'Riordan ◽  
Tauseef Mohyuddin ◽  
Manus Moloney
Keyword(s):  
Positron Emission Tomography ◽  
Bone Biopsy ◽  
Kidney Injury ◽  
Ct Scanning ◽  
Emission Tomography ◽  
Lower Back ◽  
Positron Emission ◽  
Pet Ct ◽  
History Of ◽  
The Right

A 43-year-old man presented to hospital after routine laboratory tests showed an acute kidney injury and hypercalcaemia. He had no relevant medical history and normal physical examination, other than a 6-week history of lower back pain for which he had been taking naproxen. Low parathyroid hormone (PTH) levels indicated a PTH-independent hypercalcaemia. Investigations including CT of thorax, abdomen and pelvis and subsequent bone biopsy and renal biopsy were unremarkable. Positron emission tomography/CT (PET/CT) scan was ultimately considered as a diagnostic test and showed abnormalities in the right subpectoral and portacaval region with intense fluorodeoxyglucose F 18 uptake in local lymph nodes. A biopsy of the right subpectoral node showed granulomatous change consistent with sarcoidosis. PET/CT scanning can play an important role in the investigation of suspected malignancy, infection and inflammatory disease and in this case, was required to diagnose an atypical presentation of sarcoidosis.

scholarly journals Additive value of positron emission tomography/computed tomography scan for detection of aortic tube graft infection: a case report

2020 ◽  
Author(s):  
Farnoosh Larti ◽  
Mohammad Amin Khadembashiri ◽  
Mehrshad Abbasi ◽  
Alborz Sherafati
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Diagnostic Accuracy ◽  
Ct Scan ◽  
Graft Infection ◽  
Emission Tomography ◽  
Positron Emission ◽  
Pet Ct ◽  
History Of ◽  
Pet Ct Scan

Abstract Background Diagnosis of aortic graft infection is challenging, and delayed diagnosis is associated with poor prognosis. Positron emission tomography/computed tomography (PET/CT) has improved diagnostic accuracy. Case summary A patient with a history of congenital heart disease was admitted due to fever. He had a history of four cardiac surgeries, including the Bentall procedure for endocarditis. Blood cultures were negative. A semi-mobile mass was detected in the distal portion of the aortic tube graft in echocardiography. PET/CT scan was used to confirm tube graft infection and to support proceeding to cardiac surgery. Discussion Using multimodality imaging, including PET/CT scan in combination with echocardiography, can improve diagnostic accuracy for the detection of aortic tube graft infection, infection of prosthetic valves, or intra-cardiac devices, especially in high-risk surgical cases.

scholarly journals The use of PET/CT in pregnancy: A case report of malignant parathyroid carcinoma and a review of the literature

2017 ◽  
Vol 11 (1) ◽  
pp. 45-49 ◽  
Author(s):  
Manpreet (Mona) Gill ◽  
Winnie Sia ◽  
Michael Hoskinson ◽  
Erin Niven ◽  
Rshmi Khurana
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Parathyroid Carcinoma ◽  
Emission Tomography ◽  
Positron Emission Tomography Scanning ◽  
Healthy Baby ◽  
Positron Emission ◽  
Pet Ct ◽  
History Of ◽  
In Pregnancy

Positron emission tomography scanning is not commonly performed in pregnancy but can be done if required. Fetal doses of radiation can be minimized, and our case exemplifies the safe application of positron emission tomography/computed tomography in pregnancy. A 38-year-old woman in her first ongoing pregnancy presented at 28 weeks’ gestation with symptomatic hypercalcemia. Given a history of parathyroid carcinoma, recurrence was suspected. Ultrasound and magnetic resonance imaging failed to locate the lesion. However, positron emission tomography/computed tomography identified a culprit supraclavicular lymph node. This was excised under local anesthesia resulting in normalization of parathyroid hormone and calcium levels. A term, healthy baby was delivered. The literature provides support that the use of positron emission tomography/computed tomography is acceptable when indicated, and there are modifications to protocols that can further limit risk.

scholarly journals Neurosarcoidosis Pathologically Diagnosed Via Biopsy of a Normal-Sized Inguinal Lymph Node With Fluorodeoxyglucose Accumulation on Positron Emission Tomography/Computed Tomography in a Patient With a History of Brain Ewing’s Sarcoma

2021 ◽  
Author(s):  
Masayuki Fuwa ◽  
Shodai Tateyama ◽  
Ayaka Kato ◽  
Motochika Asano ◽  
Koichiro Taguchi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Lymph Node ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Inguinal Lymph Node ◽  
Emission Tomography ◽  
Positron Emission ◽  
Pet Ct ◽  
History Of

Abstract Neurosarcoidosis is a rare disease and is often difficult to diagnose. Herein, we report a case of neurosarcoidosis in a patient with a history of Ewing’s sarcoma of the brain. He presented with fever of unknown origin, and a pathological diagnosis was obtained via biopsy of a normal-sized inguinal lymph node with fluorodeoxyglucose (FDG) accumulation on positron emission tomography/computed tomography (PET/CT). The condition could not have been diagnosed without FDG-PET/CT.

scholarly journals Accuracy of Positron Emission Tomography as a Diagnostic Tool for Lead Endocarditis: Design of the Prospective Multicentre ENDOTEP Study

2016 ◽  
Vol 11 (1) ◽  
pp. 25
Author(s):  
Sana Amraoui ◽  
Ghoufrane Tlili ◽  
Elif Hindié ◽  
Paul Perez ◽  
Olivia Peuchant ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Diagnostic Tool ◽  
Fdg Pet ◽  
Ct Scanning ◽  
Emission Tomography ◽  
Lead Extraction ◽  
Positron Emission ◽  
Pet Ct ◽  
Lead Endocarditis ◽  
Fdg Pet Ct

Background: Rates of pacemaker implantation are steadily increasing and as patients are living longer, endovenous leads remain implanted for an extended period of time thereby increasing the risk of cardiac implantable electronic device (CIED) infection. Investigating fever of unknown origin in patients with implanted pacemakers can be challenging. Recently, 18F-fluorodeoxyglucose positron emission tomography/computerised tomography (18F-FDG-PET/CT) scanning has been used as a diagnostic tool for lead endocarditis in small studies. Objectives: ENDOTEP is a prospective and multicentre study designed to evaluate the accuracy of 18F-FDG-PET/CT scanning in the diagnosis of lead endocarditis. Methods: A total of 250 patients referred for pacemaker extraction due to suspicion of an infected device will be prospectively enrolled in six French regional centres for investigation and treatment of CIED infection. 18F-FDG-PET/CT scanning (index test) will be performed in each patient in the 48 hours preceding lead extraction. Bacteriological cultures (reference standard) will assess the presence of lead endocarditis, blind to 18F-FDG-PET/CT results. Enrolment started in June 2015 and is expected to end by June 2017. The primary objective will be to establish the sensitivity of the 18F-FDG-PET/CT scan for lead endocarditis. Secondary objectives will include other accuracy parameters, inter-observer agreement in the interpretation of 18F-FDG-PET/CT scanning, the influence of previous antibiotic therapy on 18F-FDG-PET/CT diagnostic accuracy and assessment of septic emboli associated to lead endocarditis. Conclusion: The ENDOTEP study will examine the ability of 18F-FDG-PET/CT scanning to avoid possible false-positive results, as is common using the current usual diagnostic strategy and may lead to unnecessary extraction of implants in patients with suspected lead infection.

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