scholarly journals Deep vein thrombosis with pulmonary thromboembolism in a case of severe COVID-19 pneumonia

2021 ◽  
Vol 14 (1) ◽  
pp. e240932
Author(s):  
Sujata Devi ◽  
Sudipta Mohakud ◽  
Nilanjan Kar ◽  
Divya Muthuvel
Keyword(s):  
Deep Vein Thrombosis ◽  
Pulmonary Thromboembolism ◽  
Ground Glass ◽  
Low Molecular Weight ◽  
Colour Doppler ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
The Common ◽  
Deep Vein ◽  
D Dimer

A 53-year-old man with diabetes came to the emergency department with fever and dry cough for 5 days, swelling of the left leg for 2 days, shortness of breath and chest pain for 1 hour. He had raised temperature, tachycardia, tachypnoea, reduced oxygen saturation and swollen tender left leg on examination. The frontal chest radiograph showed bilateral ground-glass opacities; he tested positive for COVID-19 with elevated D-dimer. The colour Doppler examination of the left leg revealed acute deep vein thrombosis (DVT) of the common femoral and the popliteal veins. The chest CT showed bilateral diffuse ground-glass opacities predominantly involving peripheral zones and the lower lobes. The CTPA revealed left pulmonary thromboembolism (PTE), treated with low-molecular-weight heparin. COVID-19 predominantly affects the respiratory system. DVT and PTE are common in COVID-19 but lethal. They should be diagnosed early by clinical and radiological examinations and treated promptly with anticoagulants.

scholarly journals ROLE OF COLOUR DOPPLER IN EVALUATION OF ACUTE DEEP VEIN THROMBOSIS OF LOWER LIMB

2019 ◽  
Vol 8 (8) ◽  
pp. 512-516
Author(s):  
Vijay Bahadur Singh ◽  
Punya Pratap Singh ◽  
Rajesh Malik ◽  
Lovely Kaushal ◽  
Vijay Verma ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Lower Limb ◽  
Colour Doppler ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

Pulmonary Thromboembolism in Patients with Acute Deep Vein Thrombosis

2013 ◽  
Vol 29 (4) ◽  
pp. 133-137
Author(s):  
In Gun Hyun ◽  
Byung Sun Cho ◽  
Moon-Soo Lee ◽  
Hae Young Ahn
Keyword(s):  
Deep Vein Thrombosis ◽  
Pulmonary Thromboembolism ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein

scholarly journals Combined use of pretest clinical probability score and latex agglutination D-dimer testing for excluding acute deep vein thrombosis

2009 ◽  
Vol 50 (5) ◽  
pp. 1099-1105 ◽  
Author(s):  
Takashi Yamaki ◽  
Motohiro Nozaki ◽  
Hiroyuki Sakurai ◽  
Yuji Kikuchi ◽  
Kazutaka Soejima ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Latex Agglutination ◽  
Probability Score ◽  
Vein Thrombosis ◽  
Clinical Probability ◽  
Combined Use ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein ◽  
D Dimer

scholarly journals Factors affecting the recurrence in patients with venous thromboembolism: A retrospective cohort study

2021 ◽  
Vol 29 (3) ◽  
pp. 384-390
Author(s):  
Yasemin Ateş ◽  
Züleyha Bingöl ◽  
Gülfer Okumuş ◽  
Orhan Arseven
Keyword(s):  
Risk Factors ◽  
Deep Vein Thrombosis ◽  
Venous Thromboembolism ◽  
Pulmonary Thromboembolism ◽  
First Year ◽  
Factors Affecting ◽  
Vein Thrombosis ◽  
Hereditary Risk ◽  
Deep Vein ◽  
D Dimer

Background: The aim of the study was to evaluate the frequency of recurrence and the risk factors for recurrence in patients who were diagnosed with venous thromboembolism. Methods: Between January 2005 and January 2015, a total of 412 venous thromboembolism patients (164 males, 248 females; mean age: 53.5±16.6 years; range: 19 to 95 years) were retrospectively analyzed. The demographics, underlying risk factors, comorbidities, imaging findings, and treatment data of the patients were recorded. Results: At least one transient/permanent risk factor was found in 341 (82.7%) of the index events, and the other 71 (17.2%) were idiopathic. Recurrence developed in 76 (18.4%) of the patients. The duration of the treatment in the first event was significantly longer in recurrent cases (p=0.007). The recurrence rate in patients diagnosed with only deep vein thrombosis or patients diagnosed with pulmonary thromboembolism + deep vein thrombosis was significantly higher than the patients diagnosed with only pulmonary thromboembolism (24% vs. 14.2%, respectively; p=0.007). The rate of idiopathic venous thromboembolism was higher in recurrent cases than in non-recurrent cases (26.3% vs. 15.2%, respectively; p=0.028). At the end of the first year, the mean D-dimer levels were higher in recurrent cases (p=0.034). Hereditary risk factors were also higher in recurrent cases (39.5% vs. 19.3%, respectively; p=0.031). There was no significant correlation between recurrence and mortality. Conclusion: The presence of deep vein thrombosis, idiopathic events, high D-dimer levels at the end of the first year and hereditary risk factors seem to be associated with recurrence.

LEVELS OF FACTOR VIII (FVIII), D-DIMER AND THROMBIN GENERATION (TG) IN PATIENTS AFTER ACUTE DEEP VEIN THROMBOSIS (DVT)

2007 ◽  
Vol 5 ◽  
pp. P-S-602-P-S-602
Author(s):  
A.J. ten Cate ◽  
A.W.J.H. Dielis ◽  
H.M.H. Spronk ◽  
R. van Oerle ◽  
K. Hamulyák ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Factor Viii ◽  
Thrombin Generation ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein ◽  
D Dimer

The diagnosis and treatment of venous thromboembolism

Hematology ◽  
2013 ◽  
Vol 2013 (1) ◽  
pp. 457-463 ◽  
Author(s):  
Philip Wells ◽  
David Anderson
Keyword(s):  
Molecular Weight ◽  
Deep Vein Thrombosis ◽  
Venous Thromboembolism ◽  
Low Molecular Weight Heparin ◽  
Pretest Probability ◽  
Low Molecular Weight ◽  
Major Hemorrhage ◽  
Vein Thrombosis ◽  
Deep Vein ◽  
D Dimer

Abstract Venous thromboembolism (VTE) is a common condition that can lead to complications such as postphlebitic syndrome, chronic pulmonary artery hypertension, and death. The approach to the diagnosis of has evolved over the years and an algorithm strategy combining pretest probability, D-dimer testing, and diagnostic imaging now allows for safe, convenient, and cost-effective investigation of patients. Patients with low pretest probability and a negative D-dimer can have VTE excluded without the need for imaging. The mainstay of treatment of VTE is anticoagulation, whereas interventions such as thrombolysis and inferior vena cava filters are reserved for special situations. Low-molecular-weight heparin has allowed for outpatient management of most patients with deep vein thrombosis at a considerable cost savings to the health care system. Patients with malignancy-associated VTE benefit from decreased recurrent rates if treated with long-term low-molecular-weight heparin. The development of new oral anticoagulants further simplifies treatment. The duration of anticoagulation is primarily influenced by underlying cause of the VTE (whether provoked or not) and consideration of the risk for major hemorrhage. Testing for genetic and acquired thrombophilia may provide insight as to the cause of a first idiopathic deep vein thrombosis, but the evidence linking most thrombophilias to an increased risk of recurrent thrombosis is limited.

Selective D-dimer testing for the diagnosis of acute deep vein thrombosis: a validation study

2013 ◽  
Vol 11 (12) ◽  
pp. 2184-2186 ◽  
Author(s):  
T. van der Hulle ◽  
M. Tan ◽  
P. L. den Exter ◽  
G. C. Mol ◽  
A. Iglesias del Sol ◽  
...  
Keyword(s):  
Deep Vein Thrombosis ◽  
Validation Study ◽  
Vein Thrombosis ◽  
Acute Deep Vein Thrombosis ◽  
Deep Vein ◽  
D Dimer
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