Open-source automated insulin delivery systems for the management of type 1 diabetes during pregnancy

2021 ◽  
Vol 14 (9) ◽  
pp. e243522
Author(s):  
Khulood Bukhari ◽  
Rana Malek
Keyword(s):  
Type 1 Diabetes ◽  
Open Source ◽  
Closed Loop ◽  
Glycated Hemoglobin ◽  
Insulin Delivery ◽  
Third Trimester ◽  
Time In Range ◽  
Insulin Delivery System ◽  
Iphone Application

A 40-year-old woman used an open-source automated insulin delivery system to manage her type 1 diabetes (T1D) prior to conception. The code for building the iPhone application called ‘Loop’ that carried the software for the hybrid closed-loop controller was available online. Her glycated hemoglobin before conception was 6.4%. Between 6 and 12 weeks gestation, she spent 66% time-in-range (TIR), 28% time-above-range (TAR) and 6% time-below-range (TBR). Between 18 and 24 weeks gestation, she spent 68% TIR, 27% TAR and 5% TBR. During her third trimester, she spent 72% TIR, 21% TAR and 7% TBR. She delivered a healthy infant with no neonatal complications. Clinicians should be aware of this technology as it gains traction in the T1D community and seeks Food and Drug Administration approval.

1065-P: The Effect of a Closed-Loop Insulin Delivery System on Glycemic Control in Type 1 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1065-P ◽  
Author(s):  
ANASTASIOS KOUTSOVASILIS ◽  
ALEXIOS SOTIROPOULOS ◽  
ANASTASIA ANTONIOU ◽  
VASILIOS KORDINAS ◽  
DESPINA PAPADAKI ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Delivery System ◽  
Closed Loop ◽  
Insulin Delivery ◽  
Insulin Delivery System

976-P: Evaluation of Hybrid Closed-Loop Insulin Delivery System for Patients with Type 1 Diabetes in Real-World Clinical Practice: A One-Year Qualitative Observational Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 976-P
Author(s):  
AHMED H. ELDIB ◽  
SHAHEEN TOMAH ◽  
SHILTON E. DHAVER ◽  
HANNAH GARDNER ◽  
MHD WAEL TASABEHJI ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Clinical Practice ◽  
Observational Study ◽  
Delivery System ◽  
Real World ◽  
Closed Loop ◽  
Insulin Delivery ◽  
Insulin Delivery System ◽  
One Year

121-LB: Early Independent View of Quality of Life in Patients with Type 1 Diabetes Using Hybrid Closed-Loop Insulin Delivery System in Real-World Clinical Practice

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 121-LB
Author(s):  
AHMED H. ELDIB ◽  
ELENA TOSCHI ◽  
NOOR MAHMOUD ◽  
MHD WAEL TASABEHJI ◽  
SAHAR ASHRAFZADEH ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Type 1 Diabetes ◽  
Clinical Practice ◽  
Delivery System ◽  
Real World ◽  
Closed Loop ◽  
Insulin Delivery ◽  
Insulin Delivery System

scholarly journals Hybrid Closed-Loop Insulin Delivery Systems for People With Type 1 Diabetes

2021 ◽  
Vol 1 (6) ◽  
Author(s):  
Health Technology Assessment Team
Keyword(s):  
Type 1 Diabetes ◽  
Closed Loop ◽  
Glucose Monitoring ◽  
Glycemic Variability ◽  
Insulin Delivery ◽  
Monitoring Methods ◽  
Expert Review ◽  
Expert Review Panel ◽  
Time In Range

The CADTH Health Technology Expert Review Panel (HTERP) suggests that hybrid closed-loop insulin delivery (HCL) systems hold promise for the care of people with type 1 diabetes. HTERP considers that, at present, there are insufficient long-term data on clinically relevant and patient-important outcomes to recommend how extensive the role of HCL systems should be in care. HTERP recommends the collection of robust and comparative data for consideration of future reassessments that compare HCL systems to existing insulin delivery and glucose monitoring methods in terms of glycated hemoglobin (hemoglobin A1C); time-in-range; time above and below range; glycemic variability; quality of life; patient, parent or caregiver, and health care provider satisfaction; diabetes-related complications; discontinuation rates; and health system impact. Robust data are collected in well-designed comparative studies that are, among other considerations, of sufficient duration to ensure a clinically meaningful outcome assessment.

scholarly journals Safety of a Hybrid Closed-Loop Insulin Delivery System in Patients With Type 1 Diabetes

JAMA ◽  
2016 ◽  
Vol 316 (13) ◽  
pp. 1407 ◽  
Author(s):  
Richard M. Bergenstal ◽  
Satish Garg ◽  
Stuart A. Weinzimer ◽  
Bruce A. Buckingham ◽  
Bruce W. Bode ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Delivery System ◽  
Closed Loop ◽  
Insulin Delivery ◽  
Insulin Delivery System

282-OR: Impact of a Hybrid Closed-Loop Insulin Delivery System on Hypoglycemia Awareness in Individuals with Type 1 Diabetes

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 282-OR
Author(s):  
MARIE-ANNE BURCKHARDT ◽  
JULIE DART ◽  
GRANT J. SMITH ◽  
MARY B. ABRAHAM ◽  
NIRUBASINI PARAMALINGAM ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Delivery System ◽  
Closed Loop ◽  
Insulin Delivery ◽  
Insulin Delivery System
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