Ultrawide field imaging to document the progression of gyrate atrophy of the choroid and retina over 5 years

2021 ◽  
Vol 14 (8) ◽  
pp. e244695
Author(s):  
Soumya Jena ◽  
Koushik Tripathy ◽  
Rohan Chawla ◽  
Ahmad M Mansour

A family of three siblings affected with gyrate atrophy of the choroid and retina is presented. Ultrawide field fundus imaging was used to monitor the progression of the disease objectively over 5 years.

Author(s):  
T. Y. Alvin Liu ◽  
J. Fernando Arevalo

Abstract Background Diabetic retinopathy (DR) is one of the leading causes of vision loss worldwide. For decades, 7-field 30-degree fundus imaging has been the gold standard for DR classification. The aim of this review article is to discuss how the advent of ultra-wide-field (UWF) fundus imaging has changed the management of proliferative diabetic retinopathy (PDR). Main body Current data suggests that UWF imaging, as compared to conventional Early Treatment Diabetic Retinopathy Study (ETDRS) fields, detects additional and more extensive PDR pathologies. DR lesions, captured by UWF imaging outside of ETDRS fields, likely carry prognostication value. Conclusion UWF imaging represents a major advancement in the detection and management of DR. It remains unclear whether, when and how patients, with PDR changes only peripheral to standard ETDRS fields, should be treated. A larger, prospective, randomized clinical trial is also needed to compare the efficacy of UWF image-guided targeted laser photocoagulation with that of conventional panretinal photocoagulation.


2009 ◽  
Vol 24 (1) ◽  
pp. 37-39 ◽  
Author(s):  
Sumit P. Shah ◽  
Atul Jain ◽  
Robert E. Coffee ◽  
Tara A. McCannel

Eye ◽  
2018 ◽  
Vol 33 (4) ◽  
pp. 587-591 ◽  
Author(s):  
Aditi Gupta ◽  
Hala El-Rami ◽  
Rasha Barham ◽  
Alan Fleming ◽  
Jano van Hemert ◽  
...  

2019 ◽  
Vol 103 (11) ◽  
pp. 1656-1659 ◽  
Author(s):  
Alessandro Marchese ◽  
Elisabetta Miserocchi ◽  
Chiara Giuffrè ◽  
Maria Vittoria Cicinelli ◽  
Giuseppe Querques ◽  
...  

AimsPeculiar retinal signs of vitreoretinal lymphoma (VRL) have been identified. However, limited information on the vitreous features of VRL is available. This study aims to characterise the vitreous involvement in VRL with the help of multimodal imaging.MethodsIn this retrospective, observational study, we reviewed charts and imaging of all patients with biopsy-proven VRL seen from January 2016 to April 2018 at a single referral centre. These included ultrawide-field imaging, ophthalmic ultrasonography and slit-lamp photography. The main outcome measures were patterns of vitreous haze of VRL, as observed by combining clinical and multimodal imaging information.ResultsTwenty-six eyes of 13 patients were included. At presentation, vitreous haze was present in 24 eyes (92%) and was the only sign of VRL in 4 eyes (15%). Three patterns of vitreous haze were identified in VRL. An aurora borealis pattern was present in 12 eyes and showed linear opacities with a myriad of cells aligned along the vitreous fibrils. A string of pearls pattern was present in two eyes at baseline and developed in other four eyes after vitrectomy, showing fine fibrils connecting bunches of inflammatory material. A non-specific pattern was observed in 10 eyes. Ophthalmic ultrasound showed corpuscular material correlating with the grading of vitreous haze.ConclusionVRL shows different patterns of vitreous haze. Multimodal imaging, including ultrawide-field imaging and slit-lamp photography, helps in recognising these patterns, raising suspicion for VRL.


Ophthalmology ◽  
2015 ◽  
Vol 122 (5) ◽  
pp. 949-956 ◽  
Author(s):  
Paolo S. Silva ◽  
Jerry D. Cavallerano ◽  
Nour Maya N. Haddad ◽  
Hanna Kwak ◽  
Kelli H. Dyer ◽  
...  

2021 ◽  
Vol 10 (15) ◽  
pp. 3300
Author(s):  
Mohamed Ashraf ◽  
Jerry D. Cavallerano ◽  
Jennifer K. Sun ◽  
Paolo S. Silva ◽  
Lloyd Paul Aiello

Ultrawide field imaging (UWF) has allowed the visualization of a significantly greater area of the retina than previous standard approaches. In diabetic retinopathy (DR), significantly more lesions are seen on UWF imaging compared to the seven-standard ETDRS fields. In addition, some eyes have lesions that are located predominantly in the peripheral retina that are associated with an increased risk of DR progression. The current DR severity scales are still largely based on clinically visible retinal microvascular lesions and do not incorporate retinal periphery, neuroretinal, or pathophysiologic changes. Thus, current scales are not well suited for documenting progression or regression in eyes with very early or advanced DR, nor in the setting of vascular endothelial growth factor inhibitors (antiVEGF). In addition, the categorical system is highly subjective, and grading is variable between different graders based on experience level and training background. Recently, there have been efforts to quantify DR lesions on UWF imaging in an attempt to generate objective metrics for classification, disease prognostication and prediction of treatment response. The purpose of this review is to examine current quantitative metrics derived from UWF fluorescein angiograms and UWF color imaging to determine their feasibility in any potential future DR classification.


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