Takotsubo cardiomyopathy associated with dydrogesterone use

2021 ◽  
Vol 14 (11) ◽  
pp. e246553
Author(s):  
Adam Ioannou
Keyword(s):  
Coronary Artery Disease ◽  
Case Report ◽  
Coronary Artery ◽  
Takotsubo Cardiomyopathy ◽  
Premenopausal Woman ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Female Sex Hormones ◽  
First Case ◽  
Artery Disease

Takotsubo cardiomyopathy is characterised by left ventricular apical ballooning, in the absence of coronary artery disease, and classically occurs at times of intense stress. Due to the striking preponderance of Takotsubo cardiomyopathy occurring in postmenopausal women, it has been postulated that female sex hormones may also be implicated in its pathogenesis. This case report describes the first case of Takotsubo cardiomyopathy associated with the initiation of dydrogesterone (a synthetic retroprogesterone) in a premenopausal woman.

Management of airway obstruction with nebulised adrenaline resulting in takotsubo cardiomyopathy: case report

2016 ◽  
Vol 130 (9) ◽  
pp. 883-886 ◽  
Author(s):  
F Keshtkar ◽  
O T Dale ◽  
W O Bennett ◽  
C E Hall
Keyword(s):  
Case Report ◽  
Airway Obstruction ◽  
Takotsubo Cardiomyopathy ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Coronary Syndrome ◽  
Wave Inversion ◽  
Acute Airway Obstruction ◽  
Artery Disease ◽  
High Index Of Suspicion

AbstractBackground:Takotsubo cardiomyopathy has been associated with the use of catecholamines; however, its development after the use of nebulised adrenaline for the management of acute airway obstruction has not previously been described.Case report:A 66-year-old man with squamous cell carcinoma of the larynx, with tumour–node–metastasis staging of T3N2cM0, confirmed by biopsy and computed tomography, presented to the emergency department with acute airway obstruction. He was treated twice with nebulised adrenaline and intravenous dexamethasone. After a period of 24 hours, cardiac rhythm changes were noted on telemetry. A 12-lead electrocardiogram showed widespread T-wave inversion and QT prolongation suggestive of an acute coronary syndrome. Coronary angiography demonstrated no coronary artery disease, but left ventricular angiography showed marked apical ballooning and apical wall akinesia consistent with a diagnosis of takotsubo cardiomyopathy.Conclusion:Takotsubo cardiomyopathy can mimic true ischaemic heart disease and the diagnosis requires a high index of suspicion in patients managed with nebulised adrenaline.

scholarly journals Takotsubo Cardiomyopathy Precipitated by Tapering of Anxiolytic Medication: A Case Report

2017 ◽  
Vol 11 ◽  
pp. 117954681774664 ◽  
Author(s):  
Christopher J Lafferty ◽  
Kristen M Lafferty ◽  
Tariq Bhat ◽  
Peter C Olson ◽  
Adam Atoot ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Health Care ◽  
Case Report ◽  
Takotsubo Cardiomyopathy ◽  
Health Care Professionals ◽  
Obstructive Coronary Artery Disease ◽  
Apical Ballooning ◽  
Enzyme Release ◽  
Electrocardiographic Changes ◽  
Artery Disease

Takotsubo cardiomyopathy is a transient apical ballooning of the left ventricle typically with electrocardiographic changes and enzyme release without evidence of obstructive coronary artery disease. It typically occurs in postmenopausal women and may have a predilection for patients with anxiety disorders. The following is a case in which we believe takotsubo cardiomyopathy was induced by the tapering of antianxiety medications. We feel that health care professionals should be aware of this possibility in such a patient population especially when they have demonstrated cardiovascular symptomatology.

scholarly journals ‘Broken heart’ in acute-on-chronic liver failure

2016 ◽  
Vol 26 (2) ◽  
pp. 131-132
Author(s):  
Ennaliza Salazar ◽  
Chee Kiat Tan ◽  
George Boon Bee Goh
Keyword(s):  
Coronary Artery Disease ◽  
Liver Failure ◽  
Takotsubo Cardiomyopathy ◽  
Myocardial Stunning ◽  
Apical Ballooning ◽  
Chronic Liver ◽  
Coronary Angiogram ◽  
Chronic Liver Failure ◽  
First Case ◽  
Artery Disease

Takotsubo cardiomyopathy usually occurs as a result of catecholamine release causing myocardial ‘stunning’ during physical or emotional stress. Typically coronary angiogram shows normal or minor coronary artery disease and echocardiogram shows apical ballooning with basal wall hyperkinesia. The prognosis is excellent with good cardiac functional recovery within days to weeks. We report the first case of takotsubo cardiomyopathy in a patient with acute-on-chronic liver failure.

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