Optic disc haemorrhage and primary open-angle glaucoma: a clinical review

2020 ◽  
pp. bjophthalmol-2019-314583 ◽  
Author(s):  
Uma Jasty ◽  
Alon Harris ◽  
Brent Siesky ◽  
Lucas W Rowe ◽  
Alice C Verticchio Vercellin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Optic Disc ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Treatment Strategies ◽  
Significant Risk ◽  
Female Gender ◽  
Open Angle ◽  
Increased Risk ◽  
Disc Haemorrhage

Studies have confirmed that optic disc haemorrhage (ODH) is a significant risk factor for the development and progression of primary open-angle glaucoma (POAG). Various populations have differing risk factors for developing POAG. As such, a literature review was conducted examining seven studies published in India, China, Japan, Australia, Korea and the USA. The goal of this review was to better identify ODH risk factors and their relationship to development and progression of POAG. Ultimately, patients with ODH have a greater risk for developing POAG across all populations analysed in this review. However, some populations demonstrated additional risk factors for ODH, such as increasing age and female gender. Paradoxically, data from several studies show that people of African descent have a reduced risk of ODH despite having increased risk of open-angle glaucoma than their Caucasian counterparts. By parsing out the complex relations between ODH and open-angle glaucoma stratified by age, gender and race, we may gain a broader understanding of glaucoma pathogenesis and derive individualised treatment strategies.

scholarly journals Systemic risk factors for developing of primary open-angle glaucoma

2018 ◽  
pp. 140-145
Author(s):  
E.A. Egorov ◽  
◽  
V.P. Erichev ◽  
A.L. Onishchenko ◽  
S.Yu. Petrov ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systemic Risk ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Systemic Risk Factors

scholarly journals Rare variants in optic disc area gene CARD 10 enriched in primary open‐angle glaucoma

2016 ◽  
Vol 4 (6) ◽  
pp. 624-633 ◽  
Author(s):  
Tiger Zhou ◽  
Emmanuelle Souzeau ◽  
Shiwani Sharma ◽  
Owen M. Siggs ◽  
Ivan Goldberg ◽  
...  
Keyword(s):  
Optic Disc ◽  
Primary Open Angle Glaucoma ◽  
Rare Variants ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Disc Area

scholarly journals Relationships between Obesity, Nutrient Supply and Primary Open Angle Glaucoma in Koreans

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 878
Author(s):  
Jae Yeun Lee ◽  
Joon Mo Kim ◽  
Kyoung Yong Lee ◽  
Bokyung Kim ◽  
Mi Yeon Lee ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Dietary Intake ◽  
Large Scale ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Multivariate Logistic Regression Analysis ◽  
Open Angle ◽  
Cross Sectional Survey ◽  
Increased Risk ◽  
Calcium Phosphorus

To investigate the association between nutrient intake and primary open angle glaucoma (POAG) in Koreans, a population-based, cross-sectional survey, the Korean National Health and Nutrition Examination Survey, was analyzed. Glaucoma diagnosis was based on criteria established by the International Society of Geographic and Epidemiologic Ophthalmology. Multivariate regression analysis was used to assess the correlation between dietary intake and the prevalence of POAG in all enrolled subjects. In the low Body mass index(BMI) group (BMI <18.5), females with POAG had significantly lower intakes of energy, protein, fat, carbohydrate, ash, calcium, phosphorus, sodium, potassium, vitamin A, B-carotene, thiamin, riboflavin, and vitamin C than their non-glaucoma counterparts, based on a multivariate logistic regression analysis (all p < 0.05). In females with a medium BMI (18.5 ≤ BMI < 23), POAG showed a significant association with lower food intake, energy, protein, calcium, phosphorus, potassium, thiamin and niacin. (all p < 0.05). Lower protein thiamine intake in medium BMI males was related to POAG. Low dietary intake of several nutrients showed an association with glaucoma in low BMI female subjects. An insufficient intake of certain nutrients may be associated with an increased risk of glaucoma in Koreans. Further large-scale cohort studies are needed to determine how specific nutrients alter the risk of glaucoma.

Dietary habits are useful as risk factors for primary open-angle glaucoma while controlling for heredity and metabolic disease

2020 ◽  
Vol 26 (3) ◽  
pp. 163-166
Author(s):  
Ioanna Mylona ◽  
Michael Chourdakis ◽  
Kali Makedou ◽  
Ioannis Tsinopoulos
Keyword(s):  
Risk Factors ◽  
Fruit Juice ◽  
Dietary Habits ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Dietary Advice ◽  
Open Angle ◽  
Outpatient Services ◽  
Salt Consumption ◽  
Two Samples

Background: Primary open-angle glaucoma (POAG) has been associated with cardiovascular and dietary risk factors. Aim: This study aimed to determine whether dietary practices correlate with POAG, after controlling for the most important risk factors, namely heredity and cardiovascular risk factors (diabetes mellitus, hypertension and dyslipidaemia). Methods: Two samples of equal sizes ( N = 100) were randomly selected from glaucoma outpatient services with and without POAG. Dietary habits and risk factors for POAG were recorded. Results: Clinical cases can be discerned from controls in 90.5% of all cases, on account of having a familial history of glaucoma, eating less meat per week which is cooked more and with more visible fat and drinking less pure fruit juice. Conclusions: Drinking pure fruit juice, consuming more meat with less visible fat cooked to a lower effect and modest salt consumption during cooking is practical and easy-to-observe dietary advice for any patients at risk or already suffering from POAG.

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