scholarly journals Effect of dietary cholesterol on plasma cholesterol concentration in subjects following reduced fat, high fibre diet.

BMJ ◽  
1987 ◽  
Vol 294 (6568) ◽  
pp. 333-336 ◽  
Author(s):  
J Edington ◽  
M Geekie ◽  
R Carter ◽  
L Benfield ◽  
K Fisher ◽  
...  
BMC Biology ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Chee Kin Then ◽  
Salome Paillas ◽  
Xuedan Wang ◽  
Alix Hampson ◽  
Anne E. Kiltie

Author(s):  
Steef Kurstjens ◽  
Eugenie Gemen ◽  
Selina Walk ◽  
Tjin Njo ◽  
Johannes Krabbe ◽  
...  

Background Hypercholesterolemia (plasma cholesterol concentration ≥5.2 mmol/L) is a risk factor for cardiovascular disease and stroke. Many different cholesterol self-tests are readily available at general stores, pharmacies and web shops. However, there is limited information on their analytical and diagnostic performance. Methods We included 62 adult patients who required a lipid panel measurement (cholesterol, high-density lipoprotein (HDL), triglycerides and LDLcalc) for routine care. The performance of five different cholesterol self-tests, three quantitative meters ( Roche Accutrend Plus, Mission 3-in-1 and Qucare) and two semi-quantitative strip tests ( Veroval and Mylan MyTest), was assessed according to the manufacturers’ protocol. Results The average plasma cholesterol concentration was 5.2 ± 1.2 mmol/L. The mean absolute relative difference (MARD) of the five cholesterol self-tests ranged from 6 ± 5% ( Accutrend Plus) to 20 ± 12% ( Mylan Mytest). The Accutrend Plus cholesterol meter showed the best diagnostic performance with a 92% sensitivity and 89% specificity. The Qucare and Mission 3-in-1 are able to measure HDL concentrations and can thus provide a cholesterol:HDL ratio. The Passing-Bablok regression analyses for the ratio showed poor performance in both self-tests ( Mission 3-in-1: y = 1.62x–1.20; Qucare: y = 0.61x + 1.75). The Accutrend Plus is unable to measure the plasma high-density lipoprotein concentration. Conclusions/interpretation: The Accutrend Plus cholesterol meter (Roche) had excellent diagnostic and analytic performance. However, several of the commercially-available self-tests had considerably poor accuracy and diagnostic performance and therefore do not meet the required qualifications, potentially leading to erroneous results. Better regulation, standardization and harmonization of cholesterol self-tests is warranted.


2005 ◽  
Vol 11 (2) ◽  
pp. 136-145
Author(s):  
Jo Paddison ◽  
Hemi Heta ◽  
Ross Flett

Understanding the distribution of Mãori across stages of health behaviour change (precontemplation, contemplation, preparation, action, maintenance) may inform the development of public health programs. In a replication and extension of a study by Nigg et al. (1999) we described the distribution of 73 Mãori male questionnaire respondents (age 18 to 59 years) across these stages for 8 healthy behaviours (avoiding dietary fat, eating fibre, reducing weight, regularly exercising, reducing stress, reducing sun exposure, using sunblock, and conducting cancer self-examinations). Respondents were also asked to rate their general health, health worries, and health locus of control. Evidence found of a continuum of change for ‘ignoring’, to ‘thinking about1 to ‘performing’ healthy behaviour provides moderate support for the idea that behaviour change is not an all-or-nothing event. There were no significant age effects. Respondents who rated their health more positively were more likely to report using sunblock, exercising regularly, and eating a high fibre diet. Respondents who felt they had more control over their health were more likely to eat a diet high in fibre. Eating a high fibre diet, exercising and managing stress were most strongly associated with the other health behaviours which may illustrate the concept of gateway behaviours proposed by Nigg et al. (1999).


2002 ◽  
Vol 43 (2) ◽  
pp. 67-73 ◽  
Author(s):  
P. A. GRAHAM ◽  
I. E. MASKELL ◽  
J. M. RAWLINGS ◽  
A. S. NASH ◽  
P. J. MARKWELL

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