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2022 ◽  
Author(s):  
Jiankang Wu ◽  
Shuai Zhang ◽  
Jiayue Xu ◽  
Junwu Dang ◽  
Qingyang Zhao ◽  
...  

Abstract The mammalian brain has an extremely complex, diversified and highly modular structure, and information dissemination in the modular brain network affects various brain diseases. Although a variety of neuromodulation techniques have been used to study the discharge characteristics of neural networks, the effects of transcranial magneto-acoustic electrical stimulation(TMAES) have rarely been mentioned. Based on the excitatory and inhibitory Izhikevich neuron model, we constructs a feed-forward neural network connected by electrical synapses and chemical synapses, and analyzes the firing frequency of the neural network under TMAES and magnetic stimulation and the differences in each layer types of firing patterns of neurons. The results showed that the discharge patterns of neurons in each layer were different, the discharge frequency of inhibitory neurons was higher than that of excited neurons, and the stimulation signal could be transmitted to the whole network layer.The maximum discharge frequency of neural network connected by electrical coupling can reach 0.94kHz, and the discharge frequency of neural network connected by chemical coupling is less than 0.5 kHz.With the increase of coupling degree, the discharge frequency of neurons in each network layer under TMAES is much greater than that under magnetic stimulation.When the induced current is less than 26.5μA/cm 2 , magnetic stimulation can promote the inhibitory neurons, and TMAES has a variety of regulatory effects on the inhibitory neurons in the neural network. The results show that TMAES has better regulation effect than magnetic stimulation, and the regulation effect is affected by neural network structure and stimulation parameters.


2021 ◽  
Vol 10 ◽  
pp. 1647-1662
Author(s):  
Dedy Anung Kurniawan ◽  
Mohammad Kemal Dermawan ◽  
Arthur Josias Simon Runtrambi

This research aims to understand the power relation and white-collar crime on managing the coastal reclamation and its implication in Indonesia that is very significant at the ontological and sociological level. The problem is very interesting to be analyzed by conducting a qualitative research method based on power theory and crime theory. Data were collected through in-depth interviews, observation, and documentation related to coastal reclamation and its implication in Indonesia. Data were analyzed by using interactive models are data reduction, data display, data verification, and supported by triangulation. The results were based on ontological and sociological levels using criminology perspective for understanding the coastal reclamation and its implication in Indonesia that are needed for providing information to stakeholders related to the regulations and sanctions. This result provides inputs for making better regulation on coastal reclamation policy in Indonesia for state agencies as public officials and practitioners.


2021 ◽  
Vol 10 ◽  
pp. 1677-1689
Author(s):  
Ida Bagus Purwalaksana ◽  
Sumartono Sumartono ◽  
Bambang Santoso Haryono ◽  
Wike Wike ◽  
Bambang Slamet Riyadi

This research aims to understand the abuse of power on managing the health service policy and its implication that is very significant in reducing marginalized soldiers’ health due at the ontological level and sociological level. The problem is very interesting to be analyzed by conducting a qualitative research method based on public policy theory, abuse of power theory, and health services theory. Data were collected through in-depth interviews, observation, and documentation related to managing the health service policy cases in Indonesia. Data were analyzed by using interactive models are data reduction, data display, data verification, and supported by triangulation. The results were based on ontological level and sociological level using public policy perspective and power perspective for improving health service policy and practice for The Indonesian Army Forces. Vision and mission of public policy on managing health service policy are needed for providing information to stakeholders related, regarding the regulations and sanctions in health service policy. This result provides inputs for making better regulation on health service policy in Indonesia for state agencies as public officials and practitioners.


Materials ◽  
2021 ◽  
Vol 14 (23) ◽  
pp. 7362
Author(s):  
Betime Nuhiji ◽  
Matthew P. Bower ◽  
William A. E. Proud ◽  
Steven J. Burpo ◽  
Richard J. Day ◽  
...  

When cured in a microwave, flat thin composite panels can experience even heat distribution throughout the laminate. However, as load and geometric complexity increase, the electromagnetic field and resulting heat distribution is altered, making it difficult to cure the composite homogeneously. Materials that absorb and/or reflect incident electromagnetic radiation have the potential to influence how the field behaves, and therefore to tailor and improve the uniformity of heat distribution. In this study, an absorber was applied to a composite with non-uniform geometry to increase heating in the location which had previously been the coldest position, transforming it into the hottest. Although this result overshot the desired outcome of temperature uniformity, it shows the potential of absorbing materials to radically change the temperature distribution, demonstrating that with better regulation of the absorbing effect, a uniform temperature distribution is possible even in non-uniform composite geometries.


2021 ◽  
Vol 1 (2) ◽  
pp. 70-75
Author(s):  
Ana Batinić ◽  
Davorka Sutlović ◽  
Maja Veršić Bratinčević ◽  
Gabriela Škorput ◽  
Martina Stolica ◽  
...  

Cosmetic preparations contain a large number of ingredients. Some of them may have negative consequences, most often in the form of allergic reactions, skin irritations, hormonal disorders, increased risk of cancer. These chemicals are most often added to protect, soften, or otherwise make the product more usable. The aim of this study was to determine the presence of some potentialy harmful substances by qualitative analysis of cosmetic products using the GC-MS method and to compare results with the data stated on the product declaration. A total of 66 samples were analyzed: 10 baby shampoos and bath products, 26 cosmetic products for the axillary area and 30 samples of creams and serums. In 4 samples of baby shampoos and bath products (40 %) the presence of pottentialy harmful ingredients were proven (parabens and phenoxyethanol), while diethyl phtalate was detected in all samples but was not stated in any of the declarations of these samples. Parabens were detected in 7.7 % of the products for application in the axillary area, although were most often not declared on products, and diethyl phthalate was detected in 19 % of these samples. In 24 samples of creams and serums (80%) the presence of potentialy harmful substances buthylhydroxytoluene, cyclopentasiloxane, cyclotetrasyloxan, benzophenone, triethanolamine, phenoxyethanol, diethylphthalate was noted. This study has proven the misleading declarations. Phthalates were most often not declared on products. Better regulation of product declarations is needed, as well as stricter controls on the impact of primary packaging on product composition after packaging.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Maja Mitrašinović-Brulić ◽  
Mihaela Buljan ◽  
Damir Suljević

Abstract Background Understanding the global prevalence and phenotypic features of polycystic ovary syndrome (PCOS) is important as geographic factors and ethnic variations can significantly alter the clinical syndrome. The aim of this study was to determine and evaluate the luteinizing hormone/follicle-stimulating hormone ratio (LH/FSH) in women with PCOS during therapy on selected endocrine and biochemical parameters. Results Women with PCOS were included in the study and were classified into two groups: women without therapy (de novo) and women with therapy for PCOS. ESHERE/ASRM criteria that require the presence of two out of three criteria: ovulatory dysfunction, hyperandrogenism, and morphological PCOS detected by ultrasound diagnostics. Electrochemiluminescence immunoassay (ECLIA) was used for FSH and insulin analysis. The enzymatic method was used to analyze the biochemical profile. There was a significant difference between the two groups in terms of the LH/FSH ratio (2.56 vs. 2.41, P=0.043), glucose (6.23 vs. 5.12, P=0.003), insulin (19.21 vs. 7.35, P=0.000), IR (3.22 vs. 1.42, P=0.000), cholesterol (5.97 vs. 4.92, P=0.002), and LDL (3.56 vs. 2.56, P=0.001). The data suggest that patients with PCOS therapy have reduced hyperinsulinemia and insulin resistance. There was a significant correlation between the LH and FSH in the de novo group, as well as the correlation between hormone levels and LH/FSH ratio in both groups. Patients with PCOS therapy have a tendency for normal body weight and reduction of severe obesity compared to patients without therapy. Clinical features such as regular menstrual cycle and the prevalence of acne and hirsutism are not significantly different between groups. Conclusion PCOS cause irregularities of the menstrual cycle, the appearance of clinical manifestations, especially changes of LH/FSH ratio. Therapy for PCOS contributes to better regulation of endocrine and biochemical parameters, especially in the reduction of hyperinsulinemia, insulin resistance, and reduced LH/FSH ratio.


2021 ◽  
Vol 19 (17) ◽  
Author(s):  
Noor Azimah Ghazali ◽  
Ibrahim Sipan ◽  
Farah Nadia Abas ◽  
Ahmad Che Yaacob

A legal research shall be secured with the idea to facilitate a future change; either in the law itself or in the manner of its administration from the production of ‘pure’ academic knowledge which is concerned legal doctrines. Therefore, this paper purpose is to propose a methodological structure for legal research within perspective Malaysian Land Law and Islamic Law to establish a regulation or amendment in the existing foundation. This paper adopts method of content analysis to understanding on the underlying reasons through expert opinions on the legal issues. The finding of this research revealed that a legal methodological framework is easily simplified in form of system theory approach. This type of methodological structure is common amongst the legal researchers, lawyers and legal scholars who embrace Pure and Applied Legal Research. The methodological structure for legal research in form of system theory shall make a better regulation proposal in the perspective of Malaysian Land Law and Islamic Law. By adopt this methodological structure; researchers shall propose new regulation or amendments as legal researchers, lawyers and legal scholars.


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