scholarly journals Ultrasound-guided superficial cervical plexus block for analgesia in patients undergoing craniotomy via suboccipital retrosigmoid approach: study protocol of a randomised controlled trial

BMJ Open ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. e034003
Author(s):  
Kun Peng ◽  
Min Zeng ◽  
Jia Dong ◽  
Xiang Yan ◽  
Dexiang Wang ◽  
...  

IntroductionScalp nerve block has been proven to be an alternative choice to opioids in multimodal analgesia. However, for the infratentorial space-occupying craniotomy, especially the suboccipital retrosigmoid craniotomy, scalp nerve block is insufficient.Methods and analysisThe study is a prospective, single-centre, randomised, paralleled-group controlled trial. Patients scheduled to receive elective suboccipital retrosigmoid craniotomy will be randomly assigned to the superficial cervical plexus block group or the control group. After anaesthesia induction, superficial cervical plexus nerve block will be performed under the guidance of ultrasound. The primary outcome is the cumulative consumption of sufentanil by the patient-controlled intravenous analgesia pump within 24 hours after surgery. Secondary outcomes include the cumulative consumption of sufentanil at other four time points and numerical rating scale pain severity score.Ethics and disseminationThe protocol (version number: 2.0, 10 April 2019) has been approved by the Ethics Review Committee of China Registered Clinical Trials (Ethics Review No. ChiECRCT-20190047). The findings of this study will be disseminated in peer-reviewed journals and at scientific conferences.Trial registration numberNCT04036812

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Hammad Nabeel Najeeb ◽  
Ahsan Waqar Khan ◽  
Athar Mukhtar Siddiqui

Purpose: This study aimed to determine analgesic efficacy of a combination of bilateral superficial cervical plexus block (BLSCPB) and standard analgesia with standard analgesia alone in patients undergoing thyroid cancer surgery under general anaesthesia.Materials and Methods: It was a randomised-controlled trial conducted at the Anaesthesia Department of the Shaukat Khanum Memorial Cancer Hospital, Lahore. A sample size of 60 patients (30 patients in each group) was calculated with 95% confidence interval and power of 80%.Results: The mean pain-free duration for the Group A (BLSCPB group) was 72 min (SD 30.1) compared to 53 min (standard deviation 30.3) for the Group B. This shows a significant reduction in pain-free duration in Group A. Average NRS pain score in the Group A at q 0, 30, 60, 90 and 120 min was (0.83, 1.83, 0.23, 1.76 and 1.49), whereas the average pain score on NRS in the Group B at the same time interval mentioned above for Group A was (2.1, 2.73, 4.53, 2.44 and 1.85)Conclusion: Administration of BLSCPB resulted in superior analgesia after thyroid cancer surgery.Key words: Analgesia, cervical plexus block, post-operative pain, regional anaesthesia, thyroidectomy


2015 ◽  
Vol 45 (1) ◽  
pp. 1
Author(s):  
Pryambodho Pryambodho ◽  
Ruth Evlin Margaretha ◽  
Aida Rosita Tantri ◽  
Harim Priyono

Pendahuluan: Blok perifer yang digunakan saat pasien teranestesi akan mengurangi kebutuhan anestesia dan analgesia selama pembedahan. Berkurangnya pemakaian opioid intraoperatif juga akan mengurangi morbiditas pascaoperatif yang berkaitan dengan opioid. Tujuan: Penelitian dilakukan untuk mengetahui peran Blok Pleksus Servikal Superfisialis (BPSS) dalam mengurangi konsumsi fentanil intraoperatif, menstabilkan hemodinamik intraoperatif, dan mempercepat waktu pulih pada timpanomastoidektomi dalam anestesia umum. Metode: Penelitian ini merupakan uji klinis acak tersamar tunggal yang dilakukan di RSCM selama bulan September-November 2013 pada 32 pasien usia 19-65 tahun, ASA I-III dengan berat badan 35-80 kg yang dibagi menjadi dua kelompok. Hasil: Pada kelompok BPSS, dilakukan BPSS sebelum induksi menggunakan bupivakain 0,5%, sedangkan pada kelompok kontrol tidak dilakukan. Anestesia dipertahankan dengan FGF 0,8-1,6 lpm, compress air: O2 (konsentrasi 40%); isofluran ±1 MAC dan atrakurium 0,25 mg/kgBB setiap 30 menit untuk menjaga nilai BIS 45-60. Fentanil diberikan setiap ada peningkatan tekanan darah sistolik atau frekuensi nadi ≥20% dari nilai 5 menit sebelumnya. Saat 30 menit sebelum operasi selesai diberikan parasetamol 1 gram iv dan ondansetron 4 mg iv. Rerata konsumsi fentanil intraoperatif, tekanan darah sistolik, dan frekuensi nadi kelompok BPSS lebih rendah dan bermakna secara statistik dibandingkan kelompok kontrol: 150 mcg vs 262,5 mcg, p<0,001; 104 (90-112) vs 120 (110-130), p<0,001 dan 68 (62-86) vs 80 (68-100), p<0,001. Kesimpulan: Pemberian blok pleksus servikal superfisialis sebelum induksi mengurangi konsumsi fentanil intraoperatif, menekan respon hemodinamik terhadap insisi kulit, dan mempercepat waktu pulih pada timpanomastoidektomi dalam anestesia umum. Kata kunci: anestesia umum, blok pleksus servikal superfisialis, kecepatan waktu pulih, konsumsi fentanil, timpanomastoidektomiABSTRACT Background: The peripheral block combined with general anesthesia reduces intraoperative anesthesia and analgesia requirement. Reduced opioid consumption decreases postoperative morbidity related to opioid. Purpose: The aim of this study was to assess the role of superficial cervical plexus block (SCPB) before induction in reducing fentanyl consumption, stabilizing intraoperative hemodynamic, and speeding up recovery time in tympanomastoidectomy.  Methods: This single blind randomized clinical trial was conducted in RSCM from September to November 2013 on 32 ASA I-III patients, 13-65 years old, with body weight range 35-85 kg which were randomized into 2 groups. Result: SCPB was performed in SCPB group before induction using bupivacaine 0.5%, whereas in the control group was not performed. Anesthesia was maintained with FGF 0,8-1,6 lpm, compress air: O2 with O2 consentration 40%, isoflurane ± 1 MAC, and atracurium 0,5 mg/kgBW every 30 minutes to keep BIS level 45-60. Fentanyl was given when there was an increase in systolic blood pressure or pulse rate ≥20% more than the value of 5 minutes previously. Paracetamol 1 g iv and ondansetron 4 mg iv were given 30 minutes before the end of the surgery. The average intraoperative fentanyl consumption, systolic blood pressure, and pulse rate was lower and statistically significant in BPSS group compared to the control group: 150 mcg vs 262,5 mcg, p<0,001; 104 (90-112) vs 120 (110-130), p<0,001 and 68 (62-86) vs 80 (68-100), p<0,001 Conclusion: Administration of SCBP before induction, reduced the intraoperative fentanyl consumption, suppressed hemodynamic responses to skin incision and speed up recovery time on tympanomastoidectomy in general anesthesia. Keywords: general anesthesia, superficial cervical plexus block, recovery time, fentanyl consumption,tympanomastoidectomy


2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Zemedu Aweke ◽  
Wosenyeleh A. Sahile ◽  
Sileshi Abiy ◽  
Nugusu Ayalew ◽  
Adugna A. kassa

Introduction. The pain after thyroid surgery is considered of moderate intensity and short duration. Most trials showed significant reduction in pain intensity and severity of pain in patients for whom bilateral superficial cervical plexus block (BSCPB) was done. Objective. To assess the postoperative analgesic effect of BSCPB for thyroid surgery. Methods. Sixty six euthyroid patients were recruited and assigned to two groups (33 patients each). Group 1 BSCPB and Group 2 standard analgesia. The unpaired Student’s t-test and Mann–Whitney test were used for comparison. Statistical significance was stated at p value < 0.05. Results. The median postoperative pain score (NRS) was 3 in the BSCPB group and 5 in the control group (p=0.002). There was also statistically significant difference at 6th, 12th, and 24th hour showing a lower median pain score in the BSCPB group compared to the control group. The median time was (360 minutes) in the treatment group and (180 minutes) in the control group (p=0.0006). The median tramadol consumption within 24 hours is 0 mg in the BSCPB group compared to 100 mg in the control group (p=0.001). Conclusion and Recommendation. BSCPB done for thyroidectomy under general anesthesia decreases the postoperative pain score, total analgesia consumption, and time to first analgesia request.


Sign in / Sign up

Export Citation Format

Share Document