scholarly journals Development of National Cancer Database for Cost and Quality of Life (CaDCQoL) in India: a protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e048513
Author(s):  
Shankar Prinja ◽  
Jyoti Dixit ◽  
Nidhi Gupta ◽  
Nikita Mehra ◽  
Ashish Singh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Care ◽  
Healthcare Costs ◽  
National Level ◽  
National Database ◽  
Cancer Site ◽  
Economic Evaluations ◽  
National Cancer Database ◽  
Study Results

IntroductionThe rising economic burden of cancer on healthcare system and patients in India has led to the increased demand for evidence in order to inform policy decisions such as drug price regulation, setting reimbursement package rates under publicly financed health insurance schemes and prioritising available resources to maximise value of investments in health. Economic evaluations are an integral component of this important evidence. Lack of existing evidence on healthcare costs and health-related quality of life (HRQOL) makes conducting economic evaluations a very challenging task. Therefore, it is imperative to develop a national database for health expenditure and HRQOL for cancer.Methods and analysisThe present study proposes to develop a National Cancer Database for Cost and Quality of Life (CaDCQoL) in India. The healthcare costs will be estimated using a patient perspective. A cross-sectional study will be conducted to assess the direct out-of-pocket expenditure (OOPE), indirect cost and HRQOL among cancer patients who will be recruited at seven leading cancer centres from six states in India. Mean OOPE and HRQOL scores will be estimated by cancer site, stage of disease and type of treatment. Economic impact of cancer care on household financial risk protection will be assessed by estimating prevalence of catastrophic health expenditures and impoverishment. The national database would serve as a unique open access data repository to derive estimates of cancer-related OOPE and HRQOL. These estimates would be useful in conducting future cost-effectiveness analyses of management strategies for value-based cancer care.Ethics and disseminationApproval was granted by Institutional Ethics Committee vide letter no. PGI/IEC-03/2020-1565 of Post Graduate Institute of Medical Education and Research, Chandigarh, India. The study results will be published in peer-reviewed journals and presented to the policymakers at national level.

scholarly journals Burden of illness of hip fractures in elderly Dutch patients

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
T. A. Kanters ◽  
C. L. P. van de Ree ◽  
M. A. C. de Jongh ◽  
T. Gosens ◽  
L. Hakkaart-van Roijen
Keyword(s):  
Quality Of Life ◽  
Hip Fracture ◽  
Hip Fractures ◽  
Healthcare Costs ◽  
Burden Of Illness ◽  
Economic Evaluations ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Abstract Summary Patients with hip fractures experience reduced health-related quality of life and have a reduced life expectancy. Patients’ utilization of healthcare leads to costs to society. The results of the study can be used in future economic evaluations of treatments for hip fractures. Purpose Hip fractures are associated with high mortality, reduced quality of life, and increased healthcare utilization, leading to an economic burden to society. The purpose of this study is to determine the burden of illness of hip fractures in elderly Dutch patients for specific time periods after surgery. Methods Patients with a hip fracture above the age of 65 were included in the study. In the 1-year period after surgery, patients were asked to complete a set of questionnaires pre-injury (retrospectively), and 1 week, 1 month, 3 months, 6 months and 12 months after surgery. The set of questionnaires included the Euroqol 5D (EQ-5D-3L), the iMTA Medical Consumption Questionnaire (iMCQ) and iMTA Productivity Cost Questionnaire (iPCQ). Health-related quality of life was calculated using Dutch tariffs. Costs were calculated using the methodology described in the Dutch costing manual. Results Approximately 20% of patients with a hip fracture died within 1 year. Health-related quality of life was significantly reduced compared to pre-injury values, and patients did not recover to their pre-injury values within 1 year. Total costs in the first year after injury were €27,573, of which 10% were due to costs of the procedure (€2706). Total follow-up costs (€24,876) were predominantly consisting of healthcare costs. Monthly costs decreased over time. Conclusions Hip fractures lead to a burden to patients, resulting from mortality and health-related quality of life reductions, and to society, due to (healthcare) costs. The results of this study can be used in future economic evaluations.

scholarly journals Significance of Medicinal Mushrooms in Integrative Oncology: A Narrative Review

2020 ◽  
Vol 11 ◽  
Author(s):  
Michael Jeitler ◽  
Andreas Michalsen ◽  
Daniela Frings ◽  
Marisa Hübner ◽  
Moritz Fischer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Adverse Effects ◽  
Cancer Patients ◽  
Cancer Care ◽  
Controlled Clinical Trial ◽  
Medicinal Mushrooms ◽  
Positive Effects ◽  
Randomized Controlled ◽  
Study Results

Medicinal mushrooms are widely used in East Asia for the treatment of various diseases, especially in complementary cancer care. While there is a growing interest in medicinal mushrooms in Western countries and an increasing number of pre-clinical studies indicate distinct anti-cancer and regenerative properties, little is known about their potential relevance for clinical practice. This review aims to provide an overview of the clinical evidence, significance and potential role of medicinal mushrooms in complementary cancer care. Scientific databases for (randomized) controlled clinical trials evaluating whole spectrum formulations of medicinal mushrooms (mushroom powder and mushroom extracts) in cancer patients during and/or after conventional oncological treatment were searched. Eight studies met our inclusion criteria (eight randomized controlled trials, one controlled clinical trial). The medicinal mushrooms investigated were Agaricus sylvaticus (two trials), Agaricus blazei murill (two trials), Antrodia cinnamomea (one trial), Coriolus versicolor (one trial) and Ganoderma lucidum (three trials); all were compared to placebo and administered orally. A variety of cancer entities, outcomes and treatment durations were observed. Study results suggested beneficial effects of medicinal mushrooms, particularly quality of life and reduction of adverse effects of conventional therapies. Also, positive effects on antitumor activity and immunomodulation were reported, e.g., an increased activity of natural killer cells. In addition, results might suggest a longer survival of cancer patients receiving mushroom preparations, although in most studies this was not significant when compared to placebo. Adverse events of treatment with medicinal mushrooms were poorly reported; gastrointestinal reactions and a decrease in platelet cell count occurred in some cases. The methodological quality of most studies was generally unsatisfying and most results were insufficiently reported in several respects. Medicinal mushrooms may have a therapeutic potential for cancer patients during and after conventional oncological care with regards to quality of life, reduction of adverse effects of conventional care and possibly other surrogate parameters like immune function. There is an urgent need to investigate the safety and possible interactions of medicinal mushrooms. High-quality clinical research is warranted in order to clarify the potential of medicinal mushrooms in cancer therapy.

Legal Needs and Quality of Life in Cancer Care

2007 ◽  
Author(s):  
Michael A. Zevon ◽  
James P. Donnelly ◽  
Stephen Schwabish ◽  
Kerry Rodabaugh
Keyword(s):  
Quality Of Life ◽  
Cancer Care

Would you be more satisfied with your life if you travel more frequently?

2020 ◽  
Author(s):  
Chun-Chu Chen ◽  
Sui-Wen (Sharon) Zou ◽  
James F. Petrick
Keyword(s):  
Quality Of Life ◽  
Relevant Information ◽  
Life Domain ◽  
Travel And Tourism ◽  
Study Results ◽  
Personal Importance

This research intends to examine whether frequent travelers are more satisfied with their life as well as why these individuals travel more frequently than others. Derived from a sample of 500 Taiwanese respondents, the study results show that respondents attaching personal importance to tourism are more likely to gather travel-relevant information, resulting in more frequent travels. It is also found that frequent travelers are more satisfied with their life. These findings suggest that travel and tourism can be an important life domain affecting how people evaluate their overall quality of life.

Prospective Evaluation of Outcomes and Quality of Life between Operative Approaches for Esophagectomy at a Tertiary Cancer Care Centre in South India

2021 ◽  
Vol 47 (2) ◽  
pp. e52-e53
Author(s):  
Faheeem Abdulla ◽  
Chandramohan Krishnan Nair ◽  
Madhu Muralee ◽  
Wagh Mira Sudham ◽  
Bharath Veerabhadran
Keyword(s):  
Quality Of Life ◽  
Cancer Care ◽  
South India ◽  
Care Centre ◽  
Prospective Evaluation

scholarly journals Predictors and Moderators of Quality of Life Among College Students With ADHD

2017 ◽  
Vol 23 (14) ◽  
pp. 1736-1745 ◽  
Author(s):  
Trevor D. Pinho ◽  
Patricia H. Manz ◽  
George J. DuPaul ◽  
Arthur D. Anastopoulos ◽  
Lisa L Weyandt
Keyword(s):  
Quality Of Life ◽  
College Students ◽  
Drug Use ◽  
Psychosocial Treatment ◽  
Psychopharmacological Treatment ◽  
Study Results ◽  
Students With Adhd ◽  
The Relationship ◽  
Total Impact

Objective: The current study examines (a) whether ADHD among college students is associated with differences in perceptions of quality of life (QoL); (b) the moderating roles of comorbidity, drug use, psychopharmacological treatment, and psychosocial treatment; and (c) the total impact of these variables on QoL. Method: Participants were college students with and without ADHD ( N = 372) in a longitudinal study. Results: College students with ADHD were more likely to assert negative global QoL evaluations relative to non-ADHD peers. The relationship between ADHD and QoL was not altered as a function of medication treatment, comorbid psychopathology, psychosocial treatment, or drug use. Conclusion: College students with ADHD behave similarly to other adults with ADHD in that they make lower subjective global evaluations of their QoL relative to their non-ADHD agemates. Other factors associated with ADHD and QoL do not appear to moderate this relationship.

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