scholarly journals Pre-eclampsia and the risk of retinopathy of prematurity in preterm infants with birth weight <1500 g and/or <31 weeks’ gestation

2017 ◽  
Vol 1 (1) ◽  
pp. e000049 ◽  
Author(s):  
Belal Alshaikh ◽  
Omar Salman ◽  
Nancy Soliman ◽  
Anna Ells ◽  
Kamran Yusuf
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Risk Of Retinopathy

scholarly journals Correlation of Retinopathy of Prematurity with Oxygen Saturation

2021 ◽  
Vol 6 (06) ◽  
pp. 391-392
Author(s):  
Praveen S ◽  
Waris A
Keyword(s):  
Birth Weight ◽  
Oxygen Saturation ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Oxygen Therapy ◽  
Prolonged Exposure ◽  
Supplementary Oxygen ◽  
Childhood Blindness ◽  
Lower Oxygen ◽  
Proliferative Disease

Retinopathy of prematurity (ROP) is an abnormal vascular proliferative disease of retina that affects preterm infants. It is a leading cause of childhood blindness worldwide despite improvement in neonatal care and management. Earlier ROP was found to be associated with oxygen therapy only. Now it was concluded that aetiology of ROP was multifactorial but three factors have shown significant association with ROP: low gestational age (GA), low birth weight (BW), prolonged exposure to supplementary oxygen following delivery. Several investigators reported that lower oxygen saturation targets at young post-gestational ages with increased oxygen saturation targets at older post gestational ages reduced the incidence of ROP. However previous clinical studies are not conclusive.

scholarly journals Validation of ROPScore to predict retinopathy of prematurity among very low birth weight preterm infants in a southern Brazilian population

2019 ◽  
Vol 82 (6) ◽  
Author(s):  
Patricia Zanotelli Cagliari ◽  
Vanessa Carvalho Lucas ◽  
Isabela Carolina Borba ◽  
Danieli Mayumi Kimura Leandro ◽  
Carmem Luiza Gascho ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Brazilian Population

scholarly journals Validation of The DIGIROP-Birth Model in A Chinese Cohort

2021 ◽  
Author(s):  
Sizhe Chen ◽  
Rong Wu ◽  
He Chen ◽  
Wenbei Ma ◽  
Shaolin Du ◽  
...  
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Receiver Operating Characteristic ◽  
Preterm Infants ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Roc Curve ◽  
Operating Characteristic ◽  
Predictive Performance ◽  
Postnatal Risk Factors

Abstract Background We aimed to validate the predictive performance of the DIGIROP-Birth model for identifying treatment-requiring retinopathy of prematurity (TR-ROP) in Chinese preterm infants to evaluate its generalizability across countries and races. Methods We retrospectively reviewed the medical records of preterm infants who were screened for retinopathy of prematurity (ROP) in a single Chinese hospital between June 2015 and August 2020. The predictive performance of the model for TR-ROP was assessed through the construction of a receiver-operating characteristic (ROC) curve and calculating the areas under the ROC curve (AUC), sensitivity, specificity, and positive and negative predictive values. Results Four hundred and forty-two infants (mean (SD) gestational age = 28.8 (1.3) weeks; mean (SD) birth weight = 1237.0 (236.9) g; 64.7% males) were included in the study. Analyses showed that the DIGIROP-Birth model demonstrated less satisfactory performance than previously reported in identifying infants with TR-ROP, with an area under the receiver-operating characteristic curve of 0.634 (95% confidence interval = 0.564–0.705). With a cutoff value of 0.0084, the DIGIROP-Birth model showed a sensitivity of 48/93 (51.6%), which increased to 89/93 (95.7%) after modification with the addition of postnatal risk factors. In infants with a gestational age < 28 weeks or birth weight < 1000 g, the DIGIROP-Birth model exhibited sensitivities of 36/39 (92.3%) and 20/23 (87.0%), respectively. Conclusions Although the predictive performance was less satisfactory in China than in developed countries, modification of the DIGIROP-Birth model with postnatal risk factors shows promise in improving its efficacy for TR-ROP. The model may also be effective in infants with a younger gestational age or with an extremely low birth weight.

scholarly journals Validation of WINROP algorithm as a screening tool for retinopathy of prematurity in a northern Spanish cohort

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Raúl Fernández-Ramón
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Predictive Value ◽  
Predictive Values ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Sensitivity Specificity ◽  
Spanish Cohort

Introduction: WINROP (Weight, Insulin-like growth factor 1, Neonatal Retinopathy of Prematurity) is a computer-based ROP risk which correlate postnatal weight gain with the developed of treatment-requiring ROP. The purpose of this study was to evaluate the ability of the WINROP algorithm to detect severe (Type 1 or Type 2) ROP in a Spanish cohort of infants. Methods: Birth weight, gestational age, and weekly weight measurements of preterm infants (>23 and <32 weeks gestation) born between 2015 and 2017 were retrospectively collected and entered in WINROP algorithm. Infants were classified according alarm activation and compared with ROP screening outcomes. Sensitivity, specificity, and predictive values were calculated. Results: A total of 109 infants were included. The mean gestational age was 29.37 ± 2.26 weeks and mean birth weight was 1178 ± 320 g. Alarm occurred in 47.7 % (52/109) of neonates, with a mean time from birth to alarm of 1.9 ± 1.4 weeks. WINROP had a sensitivity of 100% (CI 95%, 59-100), a specificity of 55.9% (CI 95%, 45.7-65.7), a positive predictive value of 13.5% (CI 95%, 11.1-16.2) and a negative predictive value of 100% (CI 95%, 93.7-100) for predicting severe ROP. Conclusion: The WINROP algorithm has proven to be a useful tool in the detection of severe ROP in our cohort. Nevertheless, in extremely preterm infants (GA <28 weeks) the results should be taken with caution and an optimization of WINROP can be necessary to improve its utility in other populations.

scholarly journals Epidemiology, Prevalence, and Incidence in Retinopathy of Prematurity

2018 ◽  
pp. 2-4
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Premature Infants ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Retinal Vasculature ◽  
Frequency Data

Retinopathy of prematurity (ROP) is a disease that occurs in premature infants with retinal vasculature with an incomplete immature retina structure. ROP affects a substantial number of preterm infants worldwide. Both the incidence and severity increase with decreasing gestational age (GA) and birth weight (BW). In this review, epidemiological history and frequency data of the disease have been summarized after evaluating studies conducted in our country and abroad.

scholarly journals Prevalence and outcome of retinopathy of prematurity in preterm infants, with low birth weight at KMCH, Tamil Nadu, India

2019 ◽  
Vol 6 (2) ◽  
pp. 264
Author(s):  
R. Nikhil ◽  
K. Rajendran ◽  
Bala Krishnan
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Gestational Age ◽  
Retinopathy Of Prematurity ◽  
Tamil Nadu ◽  
Tertiary Care ◽  
Inclusion Criteria ◽  
Very High

Background: Premature infants have avascular or incompletely vascularized retina at birth and ROP evolves over 4-5 weeks after birth. The aim of this study is to know the prevalence of retinopathy of prematurity in preterm infants, with birth weight ≤ 1500 grams and/or gestational age ≤32 weeks in a tertiary care center.Methods: The study was conducted in Kovai Medical Centre and Hospital Coimbatore in 2016. The sample size is 95 babies. All preterm infants admitted with a birth weight of ≤1500 grams and/or ≤ 32 weeks of gestation and baby those at risk of ROP.Results: 95 babies have enrolled during the study period of which 78 babies fulfilled the inclusion criteria and completed this prospective study.12 babies could not complete the follow-up protocol and 5 babies died before full vascularization of the retina. 78 babies who fulfilled the inclusion criteria were screened and 15 babies were found to have ROP. The prevalence of ROP in this study is 19.2%.Conclusions: Among the preventable causes of blindness in children, ROP figures very high on the agenda. Low birth weight and gestational age were found to be the most important risk factors for the development of ROP.

scholarly journals A predictive score for retinopathy of prematurity in very low birth weight preterm infants

Eye ◽  
2011 ◽  
Vol 26 (3) ◽  
pp. 400-406 ◽  
Author(s):  
G U Eckert ◽  
J B Fortes Filho ◽  
M Maia ◽  
R S Procianoy
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Retinopathy Of Prematurity ◽  
Very Low Birth Weight ◽  
Predictive Score
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