scholarly journals Relationship between electronically measured medication adherence and vision-related quality of life in a cohort of patients with open-angle glaucoma

2018 ◽  
Vol 3 (1) ◽  
pp. e000114 ◽  
Author(s):  
Atalie C Thompson ◽  
Sandra Woolson ◽  
Maren K Olsen ◽  
Susanne Danus ◽  
Hayden B Bosworth ◽  
...  

ObjectiveTo investigate whether electronically measured medication adherence is associated with vision-related quality of life (VRQoL) in patients with open-angle glaucoma.Methods and analysisThis is a 3-year prospective cohort study of 79 subjects with open-angle glaucoma at a Veterans Affairs medical centre. Participants returned a medication event monitoring system (MEMS) for their glaucoma eye-drops and had at least two visits with glaucoma during the study period. Those taking less than 80% of prescribed glaucoma medication doses were considered to be non-adherent. Subjects were interviewed using the National Eye Institute’s Visual Function Questionnaire-25 (VFQ-25) at baseline and after 3 years.ResultsThirty per cent (n=24/79) of participants took less than 80% of prescribed doses of their glaucoma medications at baseline. Patients who did not adhere to their medications at baseline had lower mean composite VFQ-25 scores at baseline (70.66±20.50 vs 75.91±19.12, standardised mean difference=0.27) and after 3 years (71.68±21.93 vs 76.25±21.67, standardised mean difference=0.21). Visual acuity (P=0.03), but not visual field severity (P=0.13) or medication adherence (P=0.30), was significantly associated with composite VFQ-25 score in an adjusted model.ConclusionsSubjects who were non-adherent to their glaucoma medications at baseline as assessed by a MEMS device reported lower VRQoL than adherent subjects at baseline and after 3 years. However, visual acuity was significantly associated with VRQoL. Future studies should assess whether improved adherence to eye-drops impacts VRQoL in patients with glaucoma.

Eye ◽  
2017 ◽  
Vol 31 (10) ◽  
pp. 1480-1487 ◽  
Author(s):  
Y-S Kuo ◽  
C J-L Liu ◽  
H-C Cheng ◽  
M-J Chen ◽  
W-T Chen ◽  
...  

Author(s):  
Виктор Афанасьевич Иванов ◽  
Борис Дмитриевич Жидких ◽  
Татьяна Игоревна Субботина ◽  
Дарья Николаевна Бельчикова ◽  
Александр Викторович Иванов ◽  
...  

Во многих странах продолжается увеличение заболеваемости первичной открытоугольной глаукомой, а гериатрический статус пациентов ухудшается. В связи с этим актуальным является коррекция гериатрического статуса. Цель исследования - изучение гериатрического статуса пациентов, страдающих ПОУГ, после проведения селективной лазерной трабекулопластики. Результаты исследования базируются на комплексном офтальмологическом и гериатрическом обследовании до и после проведения селективной лазерной трабекулопластики. При изучении гериатрического статуса проведен анализ изменений таких гериатрических синдромов как зрительный дефицит, индекс качества жизни, депрессивный синдром. В ходе исследования установлено позитивное влияние селективной лазерной трабекулопластики на величину снижения зрительного дефицита. Так, острота зрения без коррекции и максимальная корригированная острота зрения после проведенного оперативного вмешательства повысились соответственно с 0,51±0,02 до 0,6±0,01 и с 0,62±0,02 до 0,68±0,01. Однако селективная лазерная трабекулопластика не изменила уровень депрессии, а интегральный показатель качества жизни имел тенденцию к снижению с 438,6±3,9 баллов до 429,4±3,8 баллов. Это указывает на необходимость коррекции гериатрического статуса больных с первичной открытоугольной глаукомой In many countries, the incidence of primary open-angle glaucoma continues to increase, and the geriatric status of patients is deteriorating. In this regard, the correction of geriatric status is relevant. The aim of the study was to study the geriatric status of patients suffering from POAG after selective laser trabeculoplasty. The results of the study are based on a comprehensive ophthalmological and geriatric examination before and after selective laser trabeculoplasty. When studying the geriatric status, the analysis of changes in such geriatric syndromes as visual deficit, quality of life index, and depressive syndrome was carried out. The study found a positive effect of selective laser trabeculoplasty on the reduction of visual deficit. Thus, the visual acuity without correction and the maximum corrected visual acuity after the surgical intervention increased, respectively, from 0.51±0.02 to 0.6±0.01 and from 0.62±0.02 to 0.68±0.01. However, selective laser trabeculoplasty did not change the level of depression, and the integral indicator of quality of life tended to decrease from 438.6±3.9 points to 429.4±3.8 points. This indicates the need to correct the geriatric status of patients with primary open-angle glaucoma


2013 ◽  
Vol 229 (4) ◽  
pp. 227-234 ◽  
Author(s):  
Christian Wolfram ◽  
Katrin Lorenz ◽  
Lusine Breitscheidel ◽  
Yves Verboven ◽  
Norbert Pfeiffer

2015 ◽  
Vol 94 (5) ◽  
pp. e278-e286 ◽  
Author(s):  
Irene Floriani ◽  
Luciano Quaranta ◽  
Eliana Rulli ◽  
Andreas Katsanos ◽  
Luigi Varano ◽  
...  

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