Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review

ObjectiveEvaluate effectiveness and harms of interventions for patellar tendon related pain in children and adolescents.DesignSystematic review and meta-analysis.Data sourcesMedline via Pubmed, Embase via OVID, CINAHL via Ebsco, SportDiscus up until 24 November 2017 were searched.Eligibility criteria for selecting studiesInclusion criteria were (1) controlled or randomised controlled clinical trials (RCTs), (2) participants with diagnosis of patellar tendon related disorder, (3) participants≤18 years of age at enrolment and (4) published in a peer-reviewed English or Scandinavian language journal.ResultsOf 530 studies identified, eight were included after screening, with three included in data synthesis. To be included in data synthesis, we required studies to have included (and have data available for) a minimum of 10 participants under 18 years. All studies were rated as being at high risk of bias. For adolescents with patellar tendinopathy, one RCT compared eccentric exercises to usual care and found no difference between groups. In adolescents with Osgood-Schlatter disease (OSD), injection of local anaesthetic with dextrose proved superior to either usual care or local anaesthetic alone (three armed RCTs). In a retrospective case controlled study in adolescents with OSD, surgery provided no benefit over conservative management in terms of persistent symptoms and had a higher complication rate.ConclusionThere is weak evidence to support the use of dextrose injection with local anaesthetic and no evidence to support the use of specific types of exercises to treat children/adolescents with OSD/patellar tendinopathy. Until further evidence arises, clinicians should include load modification and advise on a return to sport based on symptoms.

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Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis

Chronic Respiratory Disease ◽

10.1177/14799731211002240 ◽

2021 ◽

Vol 18 ◽

pp. 147997312110022

Author(s):

Kevin Cares-Marambio ◽

Yessenia Montenegro-Jiménez ◽

Rodrigo Torres-Castro ◽

Roberto Vera-Uribe ◽

Yolanda Torralba ◽

...

Keyword(s):

Systematic Review ◽

Chest Pain ◽

Hospital Admission ◽

Respiratory Symptoms ◽

Meta Analysis ◽

Pooled Analysis ◽

Data Synthesis ◽

Recent Onset ◽

Persistent Symptoms

Knowledge on the sequelae of Coronavirus Disease 2019 (COVID-19) remains limited due to the relatively recent onset of this pathology. However, the literature on other types of coronavirus infections prior to COVID-19 reports that patients may experience persistent symptoms after discharge. To determine the prevalence of respiratory symptoms in survivors of hospital admission after COVID-19 infection. A living systematic review of five databases was performed in order to identify studies which reported the persistence of respiratory symptoms in COVID-19 patients after discharge. Two independent researchers reviewed and analysed the available literature, and then extracted and assessed the quality of those articles. Of the 1,154 reports returned by the initial search nine articles were found, in which 1,816 patients were included in the data synthesis. In the pooled analysis, we found a prevalence of 0.52 (CI 0.38–0.66, p < 0.01, I 2 = 97%), 0.37 (CI 0.28–0.48, p < 0.01, I 2 = 93%), 0.16 (CI 0.10–0.23, p < 0.01, I 2 = 90%) and 0.14 (CI 0.06–0.24, p < 0.01, I 2 = 96%) for fatigue, dyspnoea, chest pain, and cough, respectively. Fatigue, dyspnoea, chest pain, and cough were the most prevalent respiratory symptoms found in 52%, 37%, 16% and 14% of patients between 3 weeks and 3 months, after discharge in survivors of hospital admission by COVID-19, respectively.

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Do Children and Adolescents With Mild Traumatic Brain Injury and Persistent Symptoms Benefit From Treatment? A Systematic Review

Journal of Head Trauma Rehabilitation ◽

10.1097/htr.0000000000000114 ◽

2015 ◽

Vol 30 (5) ◽

pp. 324-333 ◽

Cited By ~ 15

Author(s):

Renata Winkler ◽

Nicholas F. Taylor

Keyword(s):

Systematic Review ◽

Traumatic Brain Injury ◽

Brain Injury ◽

Children And Adolescents ◽

Mild Traumatic Brain Injury ◽

Persistent Symptoms

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Phytosterol supplementation in the treatment of dyslipidemia in children and adolescents: a systematic review

Revista Paulista de Pediatria ◽

10.1590/1984-0462/2021/39/2019389 ◽

2021 ◽

Vol 39 ◽

Author(s):

Luisa Montone Mantovani ◽

Camila Pugliese

Keyword(s):

Systematic Review ◽

Children And Adolescents ◽

Web Of Science ◽

Ldl Cholesterol ◽

Hdl Cholesterol ◽

Data Synthesis ◽

Good Tolerance ◽

Cholesterol Levels ◽

Long Term Effect

ABSTRACT Objective: To carry out a systematic review on the effects of phytosterol supplementation on the treatment of dyslipidemia in children and adolescents. Data sources: Review in the SciELO, Lilacs, Bireme, PubMed and Web of Science databases, with no time limit. Descriptors: phytosterols or plant sterols and dyslipidemias, hypercholesterolemia, cholesterol, children, adolescent, in English and Portuguese. The articles included were published in Portuguese, English or Spanish and evaluated the effect of phytosterol supplementation in pediatric patients with dyslipidemia. Documents that involved adults or animals, review papers, case studies and abstracts were excluded. Two authors performed independent extraction of articles. Of 113 abstracts, 19 were read in full and 12 were used in this manuscript. Data synthesis: Phytosterol supplementation to reduce cholesterol levels has been shown to be effective in reducing LDL-cholesterol levels by approximately 10%, with reductions above 10% in LDL-cholesterol levels observed after 8 to 12 weeks of intervention. Studies have not shown significant changes in HDL-cholesterol and triglyceride levels. Based on the absence of adverse effects, its use seems to be safe and of good tolerance in children and adolescents. Conclusions: Phytosterol supplementation seems to be of great therapeutic aid for the treatment of hypercholesterolemia in children and adolescents. Further studies assessing the long-term effect of phytosterol supplementation are necessary.

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Anthropometric Outcomes of Children and Adolescents Using Telehealth with Weight Management Interventions Compared to Usual Care: A Systematic Review and Meta-analysis

Journal of the American College of Nutrition ◽

10.1080/07315724.2020.1852982 ◽

2021 ◽

pp. 1-24

Author(s):

Cheryl A Margetin ◽

Diane Rigassio Radler ◽

Kyle Thompson ◽

Jane Ziegler ◽

Margaret Dreker ◽

...

Keyword(s):

Systematic Review ◽

Usual Care ◽

Children And Adolescents ◽

Weight Management ◽

Meta Analysis ◽

Management Interventions

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Thirty-seven jump-landing biomechanical variables are associated with asymptomatic patellar tendon abnormality and patellar tendinopathy: A systematic review

Physical Therapy in Sport ◽

10.1016/j.ptsp.2020.03.011 ◽

2020 ◽

Vol 45 ◽

pp. 38-55

Author(s):

Meaghan Harris ◽

Adrian Schultz ◽

Michael K. Drew ◽

Ebonie Rio ◽

Stuart Adams ◽

...

Keyword(s):

Systematic Review ◽

Patellar Tendon ◽

Patellar Tendinopathy ◽

Jump Landing

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OVERWEIGHT AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH PHENYLKETONURIA: A SYSTEMATIC REVIEW

Revista Paulista de Pediatria ◽

10.1590/1984-0462/2020/38/2018201 ◽

2020 ◽

Vol 38 ◽

Author(s):

Berilany dos Santos Sena ◽

Maria Izabel Siqueira de Andrade ◽

Ana Paula Ferreira da Silva ◽

Keila Fernandes Dourado ◽

Andressa Laís Ferreira Silva

Keyword(s):

Systematic Review ◽

Children And Adolescents ◽

Eating Habits ◽

Caloric Intake ◽

Overweight Child ◽

Nutritional Disorder ◽

Data Synthesis ◽

Healthy Eating Habits ◽

Nutritional Disturbances ◽

Regular Practice

ABSTRACT Objective: To verify the occurrence of overweight in children and adolescents with phenylketonuria and to identify possible causal factors. Data sources: A systematic review was performed in the SciELO, PubMed and VHL databases using the descriptors “Phenylketonurias”, “Overweight”, “Child” and “Adolescent”. Original articles conducted with children and adolescents, published between 2008 and 2018 in Portuguese, English or Spanish languages were included. Data synthesis: A total of 16 articles were identified and, after screening procedures, 6 studies were selected for the review. Overweight in children and adolescents with phenylketonuria was a frequent occurence in the studies included in this review, ranging from 7.8 to 32.6%. The female sex was the most affected by the nutritional disorder. Furthermore, a high caloric intake combined with a lack of stimuli to practice physical activities were main factors associated with the excessive weight in the population of interest. Conclusions: Excess weight can be considered a common outcome in children and adolescents with phenylketonuria. It is mainly caused by inadequate food consumption and sedentary lifestyle. The importance of early identification of nutritional disturbances in children and adolescents with phenylketonuria should be emphasized, in order to prevent associated chronic diseases and to promote health by encouraging continued healthy eating habits and the regular practice of physical exercises.

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