Chlorhexidine gluconate (corsodyl) mouthwash

1978 ◽  
Vol 16 (6) ◽  
pp. 23-24

When we reviewed chlorhexidine dental gel (Corsodyl - ICI) in the Bulletin1 we criticised the lack of evidence for its long-term efficacy for the treatment of chronic periodontal disease and suggested that it should not be used for this purpose. Now a chlorhexidine gluconate 0.2% mouthwash ‘Corsodyl’ (ICI) is being promoted as an aid in treatment and prevention of gingivitis, in the management of recurrent aphthous ulceration and oral candidiasis and to promote gingival healing following periodontal surgery.2 The pharmacology of this antiseptic was reviewed in a previous article on the gel.1

BDJ ◽  
1976 ◽  
Vol 141 (4) ◽  
pp. 118-120 ◽  
Author(s):  
M Addy ◽  
R Carpenter ◽  
W R Roberts

Author(s):  
Hugh Devlin ◽  
Rebecca Craven

Diabetes in relation to dentistry is the topic of this chapter. The incidence of diabetes is increasingly rapidly, hand-in-hand with the increase in obesity. Obesity predisposes patients to an increased insulin resistance, i.e. reduces their ability to increase the glucose transport into adipocytes, muscle, and liver cells. The pancreas responds by producing more insulin but when it can no longer produce enough to overcome the insulin resistance, the blood glucose rises. Diabetes is characterized by raised blood glucose. We describe the devastating long-term effects of diabetes, in particular the microvascular and macrovascular medical complications. The dental complications include an increased severity of periodontal disease, oral candidiasis, and dry mouth but in those who are poorly controlled the impaired defence mechanisms can lead to severe head and neck infections and osteomyelitis. A final summary lists the important clinical recommendations for treatment of diabetic patients.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Wellington F. Rodrigues ◽  
Camila B. Miguel ◽  
Ferdinando Agostinho ◽  
Gabriela V. da Silva ◽  
Javier E. Lazo-Chica ◽  
...  

Periodontal disease is an infectious inflammatory disease related to the destruction of supporting tissues of the teeth, leading to a functional loss of the teeth. Inflammatory molecules present in the exudate are catalyzed and form different metabolites that can be identified and quantified. Thus, we evaluated the inflammatory exudate present in crevicular fluid to identify metabolic biological markers for diagnosing chronic periodontal disease in older adults. Research participants were selected from long-term institutions in Brazil. Participants were individuals aged 65 years or older, healthy, or with chronic periodontal disease. Gas chromatography/mass spectrometry was used to evaluate potential biomarkers in 120 crevicular fluid samples. We identified 969 metabolites in the individuals. Of these, 15 metabolites showed a variable importance with projection   score > 1 and were associated with periodontal disease. Further analysis showed that among the 15 metabolites, two (5-aminovaleric acid and serine, 3TMS derivative) were found at higher concentrations in the crevicular fluid, indicating their potential diagnostic power for periodontal disease in older adults. Our findings indicated that some metabolites are present at high concentrations in the crevicular fluid in older adults with periodontal disease and can be used as biomarkers of periodontal disease.


1990 ◽  
Vol 6 (3) ◽  
pp. 392-402 ◽  
Author(s):  
Sigurd P. Ramfjord

AbstractThe various treatments for periodontal disease must be assessed in light of the recently articulated goals of periodontal therapy to preserve teeth for a lifetime and to enhance esthetics and comfort as well as oral health. This article examines the long-term comparisons of periodontal surgery, curettage, and scaling and root planing in improving attachment levels instead of the more traditional pocket depth.


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