Efficacy of chlorhexidine gluconate rinse for treatment and prevention of oral candidiasis in HIV-infected children: a pilot study

Author(s):  
Andrei Barasch ◽  
Monika M Safford ◽  
Ingrida Dapkute-Marcus ◽  
Daniel H Fine
1978 ◽  
Vol 16 (6) ◽  
pp. 23-24

When we reviewed chlorhexidine dental gel (Corsodyl - ICI) in the Bulletin1 we criticised the lack of evidence for its long-term efficacy for the treatment of chronic periodontal disease and suggested that it should not be used for this purpose. Now a chlorhexidine gluconate 0.2% mouthwash ‘Corsodyl’ (ICI) is being promoted as an aid in treatment and prevention of gingivitis, in the management of recurrent aphthous ulceration and oral candidiasis and to promote gingival healing following periodontal surgery.2 The pharmacology of this antiseptic was reviewed in a previous article on the gel.1


1989 ◽  
Vol 159 (4) ◽  
pp. 806-807 ◽  
Author(s):  
J. P. Crave ◽  
A. Cajot ◽  
J. Bille ◽  
M. P. Glauser

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Rafaela A. S. Alavarce ◽  
Luiz L. Saldanha ◽  
Nara Ligia M. Almeida ◽  
Vinicius C. Porto ◽  
Anne L. Dokkedal ◽  
...  

Equisetum giganteumL. (E. giganteum), Equisetaceae, commonly called “giant horsetail,” is an endemic plant of Central and South America and is used in traditional medicine as diuretic and hemostatic in urinary disorders and in inflammatory conditions among other applications. The chemical composition of the extract EtOH 70% ofE. giganteumhas shown a clear presence of phenolic compounds derived from caffeic and ferulic acids and flavonoid heterosides derived from quercitin and kaempferol, in addition to styrylpyrones.E. giganteum, mainly at the highest concentrations, showed antimicrobial activity against the relevant microorganisms tested:Escherichia coli,Staphylococcus aureus, andCandida albicans. It also demonstrated antiadherent activity onC. albicansbiofilms in an experimental model that is similar to dentures. Moreover, all concentrations tested showed anti-inflammatory activity. The extract did not show cytotoxicity in contact with human cells. These properties might qualifyE. giganteumextract to be a promising alternative for the topic treatment and prevention of oral candidiasis and denture stomatitis.


2008 ◽  
Vol 13 (3) ◽  
pp. 112-117 ◽  
Author(s):  
Chou I. Eyberg ◽  
Janine Pyrek

Abstract Products and technologies that aid health care professionals in vascular access practice save staff time, and while promoting patient safety and prevention of infection can provide excellent opportunities for evaluations to support evidence-based practice. This was an industry sponsored, prospective, single site, controlled, randomized clinical evaluation pilot study of two catheter dressings, 3M™ Tegaderm™ Chlorhexidine Gluconate (CHG) IV Securement Dressing (CHG gel dressing) (3M Health Care, St. Paul, MN) and BIOPATCH® Antimicrobial Dressing with Chlorhexidine Gluconate (BIOPATCH® Protective Disk with CHG, Johnson & Johnson, Somerville, NJ). Twelve intravascular (IV) therapy health care professionals (Clinicians) were asked for their professional evaluations of the catheter dressings: the ease of application and performance factors featured in specific questions. Catheters were secured on 12 healthy volunteers to simulate inserted jugular catheters (IJ) and peripherally inserted central catheters (PICC) using StatLock® PICC Plus and 3M™ Steri-Strip™. Each clinician applied and removed one CHG gel dressing and one CHG disk on one simulated PICC and one simulated IJ site, according to the manufacturers' instructions. The clinicians concluded, based upon a 1 to 5 rating scale, that the CHG gel dressing is better in regard to ease of application, ease of applying correctly, ease of removal, ability to visualize the insertion site, ease of training another clinician to apply the dressing, and more intuitive application. Twelve out of 12 clinicians favored the CHG gel dressing over the CHG disk in overall performance.


Mycoses ◽  
2016 ◽  
Vol 59 (7) ◽  
pp. 467-475 ◽  
Author(s):  
Saskia Preissner ◽  
Isabell Kastner ◽  
Eyke Schütte ◽  
Stefan Hartwig ◽  
Andrea Maria Schmidt-Westhausen ◽  
...  

2017 ◽  
Vol 22 (2) ◽  
pp. 721-731 ◽  
Author(s):  
Moritz Hertel ◽  
Eyke Schuette ◽  
Isabell Kastner ◽  
Stefan Hartwig ◽  
Andrea Maria Schmidt-Westhausen ◽  
...  

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