scholarly journals EPV103/#218 Nuclear features allow for highly sensitive selection of endometrial carcinomas for P53 testing

2021 ◽  
Author(s):  
E-Y Kang ◽  
N Wiebe ◽  
C Aubrey ◽  
C-H Lee ◽  
M Anglesio ◽  
...  
Keyword(s):  
Highly Sensitive ◽  
Endometrial Carcinomas ◽  
Nuclear Features ◽  
Selection Of

scholarly journals Selection of endometrial carcinomas for p53 immunohistochemistry based on nuclear features

2021 ◽  
Author(s):  
Eun Young Kang ◽  
Nicholas JP Wiebe ◽  
Christa Aubrey ◽  
Cheng‐Han Lee ◽  
Michael S Anglesio ◽  
...  
Keyword(s):  
P53 Immunohistochemistry ◽  
Endometrial Carcinomas ◽  
Nuclear Features ◽  
Selection Of

Selection of an aptamer against Muscovy duck parvovirus for highly sensitive rapid visual detection by label-free aptasensor

Talanta ◽  
2018 ◽  
Vol 176 ◽  
pp. 214-220 ◽  
Author(s):  
Taofeng Lu ◽  
Qin Ma ◽  
Wenzhuo Yan ◽  
Yuanzhi Wang ◽  
Yuanyuan Zhang ◽  
...  
Keyword(s):  
Visual Detection ◽  
Muscovy Duck ◽  
Label Free ◽  
Highly Sensitive ◽  
Muscovy Duck Parvovirus ◽  
Selection Of

Selection of a DNA Aptamer against Zearalenone and Docking Analysis for Highly Sensitive Rapid Visual Detection with Label-Free Aptasensor

2018 ◽  
Vol 66 (45) ◽  
pp. 12102-12110 ◽  
Author(s):  
Yuanyuan Zhang ◽  
Taofeng Lu ◽  
Yue Wang ◽  
Chenxi Diao ◽  
Yan Zhou ◽  
...  
Keyword(s):  
Visual Detection ◽  
Dna Aptamer ◽  
Label Free ◽  
Docking Analysis ◽  
Highly Sensitive ◽  
Selection Of

Effets du N minéral et du génotype de la plante sur la croissance et la nodulation de Faidherbia albida

2002 ◽  
Vol 80 (3) ◽  
pp. 241-254 ◽  
Author(s):  
Mahamadi Dianda ◽  
François-P. Chalifour
Keyword(s):  
Faidherbia Albida ◽  
Mineral N ◽  
Western Africa ◽  
Bradyrhizobium Strain ◽  
Aerial Parts ◽  
Highly Sensitive ◽  
Seed Origin ◽  
C And N ◽  
Growth Differences ◽  
Selection Of

Sahelian soils are recognized for their low N content, but their mineral N concentrations can often be high enough to inhibit N2 fixation in cultivated legumes. However, the quest for symbiotic plant genotypes tolerant of mineral N is poorly documented for nitrogen-fixing trees. The behaviour of N2 fixing symbioses with regard to nitrogen fertilization was observed in different Faidherbia albida (Del) A. Chev. genotypes. Twelve distinct lineages of the species, obtained from four regions of western Africa, were cultivated for 75 days in the presence of 0–6 mol·m–3 N provided as NH4NO3. Plants were separately inoculated with two Bradyrhizobium strains, and cultivated on sandy soil in a nursery. Aerial and root parts lengths and masses, collar diameters, and ratios of height to length (H/P) of taproot, and aerial to root (MA/MR) parts masses increased with increased N level. Plants showed significant growth differences linked with seed origin, and with lineage for a same origin. Genotypical variations were observed for concentrations as well as C and N total uptakes, C/N ratio measured in aerial parts, and N2 fixation. Nodule number and mass were greatly reduced in the presence of 2 mol·m–3 N. The extent of this reduction was dependent, to a lesser degree, on seed origin and Bradyrhizobium strain. Data show that F. albida – Bradyrhizobium symbiosis is highly sensitive to mineral N. It is suggested that selection of symbiotic partners for tolerance to mineral N might greatly improve the agronomic behaviour of F. albida.Key words: Faidherbia albida, lineages, Bradyrhizobium, symbiosis, nodulation, growth, ammonium nitrate.

Selection of DNA aptamers and establishment of an effective aptasensor for highly sensitive detection of cefquinome residues in milk

The Analyst ◽  
2018 ◽  
Vol 143 (13) ◽  
pp. 3202-3208 ◽  
Author(s):  
Lihui Wang ◽  
Chuchu Wang ◽  
Hao Li
Keyword(s):  
Respiratory Infection ◽  
Bovine Mastitis ◽  
Generation Cephalosporin ◽  
Sensitive Detection ◽  
Fourth Generation ◽  
Dna Aptamers ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Selection Of

Cefquinome (CFQ), which is a fourth-generation cephalosporin approved for veterinary use only, has been widely used for treating porcine or bovine respiratory infection, bovine mastitis and other diseases.

Dwarf Galaxies and Cluster Environments

2018 ◽  
Vol 14 (S344) ◽  
pp. 373-376
Author(s):  
Yasuhiro Hashimoto ◽  
J. Patrick Henry ◽  
Hans Böhringer
Keyword(s):  
Dwarf Galaxies ◽  
Dwarf Galaxy ◽  
Detection Algorithm ◽  
Diffuse Light ◽  
X Ray ◽  
Optical Images ◽  
Highly Sensitive ◽  
The Galaxy ◽  
Galaxy Populations ◽  
Selection Of

AbstractWe report an investigation of the properties of dwarf galaxies (Mr < -15) inside 26 clusters at z = 0.15 – 0.25, using the X-ray data from the Chandra archive, and optical images taken with Subaru Suprime-Cam. Our results include: 1. Investigation of the dwarf galaxy density distribution is sensitive to the background galaxies and the choice of colour selection of galaxies. 2. Cluster-centric dwarf-to-giant ratio is highly sensitive to the level of subtracted background galaxies. 3. A certain fraction of faint galaxies always remain undetected by the detection algorithm near the center of clusters, even after carefully treating the halo or extra diffuse light created by bright galaxies. The number of ‘undetected’ faint galaxies varies significantly from cluster to cluster, and even from pointing to pointing. 4. Dwarf galaxies extend up to 2 Mpc from the center in most clusters. Meanwhile, the distribution of blue dwarf galaxies extends more to the outside. 5. For a given colour, the spatial distributions of dwarf galaxies and giant galaxies become similar. Namely, the most of the radial distribution comes from the colour, rather than the size, of galaxies. 6. Relative to the NFW profile, all of the galaxy populations are showing a deficit near the cluster core (r < 0.3 Mpc). 7. The dwarf-to-giant ratio shows no variation against cluster measures such as the richness and X-ray luminosity, as well as various cluster X-ray characteristics related to possible dynamical status of clusters.

scholarly journals Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays

2015 ◽  
Vol 87 (23) ◽  
pp. 11907-11914 ◽  
Author(s):  
Martín A. Rossotti ◽  
Macarena Pirez ◽  
Andres Gonzalez-Techera ◽  
Yongliang Cui ◽  
Candace S. Bever ◽  
...  
Keyword(s):  
Highly Sensitive ◽  
Selection Of

scholarly journals Results and experiences after 2000 performed hysteroscopies

2012 ◽  
Vol 140 (11-12) ◽  
pp. 728-731 ◽  
Author(s):  
Vesna Kopitovic ◽  
Dragan Budakov ◽  
Aleksandra Trninic-Pjevic ◽  
Sonja Pop-Trajkovic ◽  
Srdjan Djurdjevic ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Operative Procedure ◽  
Uterine Cavity ◽  
Gynecology And Obstetrics ◽  
Highly Sensitive ◽  
Bipolar Energy ◽  
Anesthesia Technique ◽  
Novi Sad ◽  
Endometrial Carcinomas ◽  
Everyday Problems

Introduction. Hysteroscopy is one of the oldest endoscopic procedures which uses the cervix for introducing a telescope to place a camera into the uterine cavity. Objective The aim of the study was to present our experiences with this procedure during the long-term work starting from the time when hysteroscopic method of treatment was first introduced at this Clinic until today. Methods. This prospective study involved 2000 female patients referred to the Clinic for Gynecology and Obstetrics in Novi Sad from January 2005 till January 2011 for diagnostic and operative hysteroscopy. The following parameters were analyzed: the presence of minor and major pathology of the endometrium, type of anesthesia, technique of operative work, instruments and energy used during hysteroscopy and complications. Results. Seventy-eight percent of all procedures were done under intravenous anesthesia. The most common operative procedure was polypectomy and the most complicated one was myomectomy. By histopathological examination of hysteroscopic biopsy specimens four endometrial carcinomas were revealed. The combination of mechanical instrument and bipolar energy were used in most of the cases, while the percentage of complications was extremely low. Conclusion. Hysteroscopy is a safe, highly sensitive, precise diagnostic and operative endoscopic procedure. Our experiences and dilemmas open a field for discussion and offer salutations to everyday problems. The introduction of this procedure into out-patients conditions has contributed to the efficiency of the treatment of vaginal pathological processes, thus enabling that the method has become available to all gynecologists. This fact requires further study and new results.

scholarly journals PEIS: a novel approach of tumor purity estimation by identifying information sites through integrating signal based on DNA methylation data

2019 ◽  
Vol 20 (S22) ◽  
Author(s):  
Shudong Wang ◽  
Lihua Wang ◽  
Yuanyuan Zhang ◽  
Shanchen Pang ◽  
Xinzeng Wang
Keyword(s):  
Dna Methylation ◽  
Strong Correlation ◽  
Estimation Methods ◽  
Methylation Data ◽  
Tumor Purity ◽  
Novel Approach ◽  
Highly Sensitive ◽  
Number Variation ◽  
High Consistency ◽  
Selection Of

Abstract Background Tumor purity plays an important role in understanding the pathogenic mechanism of tumors. The purity of tumor samples is highly sensitive to tumor heterogeneity. Due to Intratumoral heterogeneity of genetic and epigenetic data, it is suitable to study the purity of tumors. Among them, there are many purity estimation methods based on copy number variation, gene expression and other data, while few use DNA methylation data and often based on selected information sites. Consequently, how to choose methylation sites as information sites has an important influence on the purity estimation results. At present, the selection of information sites was often based on the differentially methylated sites that only consider the mean signal, without considering other possible signals and the strong correlation among adjacent sites. Results Considering integrating multi-signals and strong correlation among adjacent sites, we propose an approach, PEIS, to estimate the purity of tumor samples by selecting informative differential methylation sites. Application to 12 publicly available tumor datasets, it is shown that PEIS provides accurate results in the estimation of tumor purity which has a high consistency with other existing methods. Also, through comparing the results of different information sites selection methods in the evaluation of tumor purity, it shows the PEIS is superior to other methods. Conclusions A new method to estimate the purity of tumor samples is proposed. This approach integrates multi-signals of the CpG sites and the correlation between the sites. Experimental analysis shows that this method is in good agreement with other existing methods for estimating tumor purity.

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