scholarly journals HPV and histological status of pelvic lymph node metastases in cervical cancer: a prospective study

2004 ◽  
Vol 57 (5) ◽  
pp. 472-476 ◽  
Author(s):  
K Lukaszuk
2020 ◽  
Author(s):  
Kenta Yoshida ◽  
Eiji Kondo ◽  
Tsuyoshi Matsumoto ◽  
Shintaro Maki ◽  
Michiko Kaneda ◽  
...  

Abstract Backgroud: Extended-field concurrent chemoradiation therapy (Ex-CCRT) is widely used for para-aortic lymph node (PAN) metastasis confirmed by radiographic assessment without surgical assessment. The objective of this prospective study was to evaluate the clinical value of laparoscopic retroperitoneal PAN biopsy in locally advanced cervical cancer (LACC) with pelvic lymph node metastases.Methods: From May 2017 to March 2020, patients with stage IIB-IIIB cervical cancer, who were diagnosed with pelvic node metastasis using positron emission tomography-computed tomography (PET-CT) with SUVmax ≥ 2.0, underwent laparoscopic retroperitoneal PAN biopsy. The radiation fields were extended to the PAN area with pathological metastases.Results: Fourteen patients were diagnosed with squamous cell carcinoma of the cervix at FIGO stage IIB (n=7) and IIIB (n=7). The median operating time was 138 (range, 104–184) minutes. The median number of harvested PANs was 19 (range, 6–36). Three patients were diagnosed as positive for PAN metastasis by histological analysis. In this study, the sensitivity and specificity of PET-CT were 66.7% and 90.9%, respectively.Conclisions: The results of this study revealed that laparoscopic retroperitoneal PAN should be the standard treatment method worldwide because it is not appropriate to determine the radiation field of PAN by image examination without performing a histological assessment.


1991 ◽  
Vol 32 (6) ◽  
pp. 449-454 ◽  
Author(s):  
S. Lähde ◽  
M. Päivänsalo ◽  
P. Rainio

In order to assess the accuracy of CT in predicting the resectability of lung cancer, a prospective study was performed on 96 patients undergoing thoracotomy. The tumors were classified preoperatively according to the TNM classification and the new international staging system for lung cancer, and scored as being resectable by lobectomy or pulmectomy, potentially resectable by lobectomy or pulmectomy, or nonresectable. Of the tumors predicted to be resectable or potentially resectable, 86.6% and 63% were radically resected, respectively, and the need for lobectomy versus pulmectomy was correctly estimated in 81.3% of them. The insufficiency of CT for defining lymph node metastases and infiltrative tumor growth was considered a marked disadvantage of the method.


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