scholarly journals P2-260 Population-based prevalence of Duchenne/Becker muscular dystrophy (DBMD) in the USA

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A293-A294
Author(s):  
P. Romitti ◽  
S. Puzhankara ◽  
G. Zamba ◽  
S. Nabukera ◽  
K. James ◽  
...  
Author(s):  
Jessica R Marden ◽  
Claudio Santos ◽  
Brian Pfister ◽  
Richard Able ◽  
Henry Lane ◽  
...  

Aim: To describe reasons for switching from prednisone/prednisolone to deflazacort and associated clinical outcomes among patients with Duchenne and Becker muscular dystrophy (DMD and BMD, respectively) in the USA. Methods: A chart review of patients with DMD (n = 62) or BMD (n = 30) who switched from prednisone to deflazacort (02/2017–12/2018) collected demographic/clinical characteristics, reasons for switching, outcomes and common adverse events. Results: The mean ages at switch were 20.1 (DMD) and 9.2 (BMD) years. The primary physician-reported reasons for switching were ‘to slow disease progression’ (DMD: 83%, BMD: 79%) and ‘tolerability’ (67 and 47%). Switching was ‘very’ or ‘somewhat’ effective at addressing the primary reasons in 90–95% of patients. Conclusion: Physician-reported outcomes were consistent with deflazacort addressing patients' primary reasons for switching.


2009 ◽  
Vol 24 (4) ◽  
pp. 425-430 ◽  
Author(s):  
Christopher Cunniff ◽  
Jennifer Andrews ◽  
F. John Meaney ◽  
Katherine D. Mathews ◽  
Dennis Matthews ◽  
...  

2012 ◽  
Vol 22 (9) ◽  
pp. 665
Author(s):  
M.M. Adams ◽  
S. Puzhankara ◽  
L.A. Miller ◽  
J. Sladky ◽  
C. Cunniff

2010 ◽  
Vol 25 (11) ◽  
pp. 1319-1324 ◽  
Author(s):  
Dennis J. Matthews ◽  
Katherine A. James ◽  
Lisa A. Miller ◽  
Shree Pandya ◽  
Kimberly A. Campbell ◽  
...  

1997 ◽  
Vol 23 (5) ◽  
pp. 399-405 ◽  
Author(s):  
J. Taylor ◽  
F. Muntoni ◽  
V. Dubowitz ◽  
C. A. Sewry

2009 ◽  
Vol 31 (6) ◽  
pp. 600-604
Author(s):  
Qian WANG ◽  
Chun-Lian JIN ◽  
Chang-Kun LIN ◽  
Wan-Ting CUI ◽  
Hong-Wei MA ◽  
...  

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Noora Knaappila ◽  
Mauri Marttunen ◽  
Sari Fröjd ◽  
Nina Lindberg ◽  
Riittakerttu Kaltiala

Abstract Background Despite reduced sanctions and more permissive attitudes toward cannabis use in the USA and Europe, the prevalences of adolescent cannabis use have remained rather stable in the twenty-first century. However, whether trends in adolescent cannabis use differ between socioeconomic groups is not known. The aim of this study was to examine trends in cannabis use according to socioeconomic status among Finnish adolescents from 2000 to 2015. Methods A population-based school survey was conducted biennially among 14–16-year-old Finns between 2000 and 2015 (n = 761,278). Distributions for any and frequent cannabis use over time according to socioeconomic adversities were calculated using crosstabs and chi-square test. Associations between any and frequent cannabis use, time, and socioeconomic adversities were studied using binomial logistic regression results shown by odds ratios with 95% confidence intervals. Results At the overall level, the prevalences of lifetime and frequent cannabis use varied only slightly between 2000 and 2015. Cannabis use was associated with socioeconomic adversities (parental unemployment in the past year, low parental education, and not living with both parents). The differences in any and frequent cannabis use between socioeconomic groups increased significantly over the study period. Conclusions Although the overall changes in the prevalence of adolescent cannabis use were modest, cannabis use increased markedly among adolescents with the most socioeconomic adversities. Socioeconomic adversities should be considered in the prevention of adolescent cannabis use.


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