Cleft lip with or without cleft palate: implication of the heavy chain of non-muscle myosin IIA

Objectives: To (1) survey Australian orthodontists about their involvement with a government-funded scheme for patients with clefts, the Medicare Cleft Lip and Cleft Palate Scheme (MCLCPS) and (2) investigate their attitude toward treating patients with clefts and their training in this respect. Design: A 13-question online survey was distributed to members of the Australian Society of Orthodontists. The survey gathered information regarding respondent demographics, the number of MCLCPS-eligible patients seen in the past 12 months and usual billing practices. Results: A total of 96 complete responses were obtained. About 70% of respondents had treated MCLCPS-eligible patients in the past 12 months and 55% saw between 2 and 5 patients during this time. The likelihood of treating patients with clefts increased by a factor of 4.8 (95% CI: 1.2-18.9) if practicing outside of a capital city and 1.5 times for each decade increase in orthodontist’s age (95% CI: 1.0-2.2). The MCLCPS was utilized by 81% of orthodontists with 26% of these respondents accepting rebate only. Most orthodontists felt their university training could have better prepared them to treat patients with clefts. A minority of orthodontists felt that a rebate increase would make them more likely to treat these patients. Conclusions: Australian orthodontists who treat patients with clefts tend to be older and work outside of capital cities. The decision to treat these patients tends to not be financially motived. Specialty orthodontic training programs could improve the preparedness of their graduates to treat patients with clefts.

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TOTAL CARE OF CHILDREN WITH CLEFT LIP AND CLEFT PALATE

The Medical Journal of Australia ◽

10.5694/j.1326-5377.1970.tb63149.x ◽

1970 ◽

Vol 2 (16) ◽

pp. 738-741

Author(s):

David L. Dey

Keyword(s):

Cleft Palate ◽

Cleft Lip ◽

Total Care

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Complete primary structure of a scallop striated muscle myosin heavy chain. Sequence comparison with other heavy chains reveals regions that might be critical for regulation.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)55085-7 ◽

1991 ◽

Vol 266 (28) ◽

pp. 18469-18476

Author(s):

L. Nyitray ◽

E.B. Goodwin ◽

A.G. Szent-Györgyi

Keyword(s):

Myosin Heavy Chain ◽

Heavy Chain ◽

Primary Structure ◽

Sequence Comparison ◽

Striated Muscle ◽

Heavy Chains ◽

Chain Sequence ◽

Muscle Myosin ◽

Complete Primary Structure

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Prevalence of Reading Difficulties in 9- to 10-Year Old Children in Sweden Born With Cleft Palate

The Cleft Palate-Craniofacial Journal ◽

10.1177/10556656211013236 ◽

2021 ◽

pp. 105566562110132

Author(s):

Justin Parry Weinfeld ◽

Jakob Åsberg Johnels ◽

Christina Persson

Keyword(s):

General Population ◽

Cleft Palate ◽

Cleft Lip ◽

Reading Difficulties ◽

Learning Problems ◽

Study Group ◽

Cross Sectional ◽

Parental Questionnaire ◽

Background Data ◽

Cross Sectional Design

Objective: To investigate the prevalence of reading difficulties in children born with cleft palate at ages 9 and 10 in Sweden. Design: Using a cross-sectional design, a parental questionnaire assessing dyslexia-like reading difficulties (Short Dyslexia Scale, SDS) was administered together with separate questions regarding background data. Participants: Families with a child born with overt cleft palate with or without cleft lip in 4 regions of Sweden. A total of 245 families were approached of which 138 families responded. Data from 136 (56%) were complete with information on cleft type and could be analyzed. Results: Twenty-two percent (95% CI, 15-30) of the whole study group displayed risk for dyslexic reading difficulties on the SDS corresponding to the 7th to 10th percentiles in the population. Children with cleft palate only had a significantly higher prevalence of reading difficulties (37%) compared to children with unilateral cleft palate (19%) and bilateral cleft palate (10%). The frequency of reading difficulties in participants with comorbidity was 32%. Among a subgroup with reported comorbidity in areas of attention, language, and learning problems, there was a 2.5 times higher risk of reading disability compared to participants without this reported comorbidity. Conclusion: The prevalence of reading difficulties in the cleft palate population was higher than in the general population. Results showed that co-occurring difficulties were common in the cleft group and that reading difficulties often appear together with other, co-occurring neurodevelopmental difficulties.

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