scholarly journals Safe Handling of Radioactive Materials

1964 ◽  
Vol 21 (4) ◽  
pp. 327-327
Author(s):  
G. E. Harrison
1989 ◽  
Vol 2 (5) ◽  
pp. 271-275 ◽  
Author(s):  
Samuel F. Liprie

Brachytherapy is treatment by implantation of one or more radioactive sources into, or near, a tumor or other cancerous area of the body. This form of cancer treatment presents new challenges for the nuclear (radiologic) pharmacist who is seeking additional unique roles within the specialty. The nuclear pharmacist is the obvious choice for active participation in brachytherapy procedures since his/her training and daily routine deals with the safe handling and use of radioactive materials. Before beginning treatment, the radioactive implant must be surveyed, calibrated, and leak tested, all of which are important aspects of nuclear pharmacy practice. Applying the basic principles of safe handling and use of radiopharmacouticals, the clinical nuclear pharmacist can easily master the art of actual implantation and removal of a brachytherapy source as well as its preparation for waste disposal. This article focuses on specifics of the brachytherapy procedure and how the clinical nuclear pharmacist can become an integral member of the brachytherapy team.


2002 ◽  
Vol 90 (2) ◽  
Author(s):  
A. S. Icenhour ◽  
L. M. Toth ◽  
G. D. Del Cul ◽  
L. F. Miller

SummaryThe safe handling and storage of radioactive materials require an understanding of the effects of radiolysis on those materials. Radiolysis may result in the production of gases (


1978 ◽  
Vol 22 ◽  
pp. 31-42
Author(s):  
D. Schiferl ◽  
R. B. Roof

X-ray diffraction studies on radioactive materials are reviewed. Considerable emphasis is placed on the safe handling and loading of not-too-exotic samples. Special considerations such as the problems of film blackening by the gamma rays and changes induced by the self-irradiation of the sample are covered. Some modifications of common diffraction techniques are presented. Finally, diffraction studies on radioactive samples under extreme conditions are discussed, with primary emphasis on high-pressure studies involving diamond-anvil cells.


1953 ◽  
Vol 32 (10) ◽  
pp. 450
Author(s):  
F.E. Simon ◽  
John Cockcroft ◽  
Henry Seligman ◽  
Burton Foringer ◽  
A.O'B Brandon ◽  
...  

1972 ◽  
Vol 70 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Mario A. Pisarev ◽  
Noe Altschuler ◽  
Leslie J. DeGroot

ABSTRACT The process of secretion of the thyroid hormone involves several steps: pinocytosis of thyroglobulin, fusion of the colloid droplets with the lysosomes, digestion of thyroglobulin by a cathepsin, dehalogenation of tyrosines and release of thyronines into the blood stream. The present paper describes a double isotope technique for studying the first two steps. Thyrotrophin (TSH) administration to rats increased the radioactivity present in all fractions, specially in the 15 000 × g pellet. When the subcellular distribution of acid phosphatase was determined, the highest specific activity was found in this fraction, thus indicating the presence of lysosomes. The content of radioactive materials in the 15 000 × g pellet was analyzed by trichloroacetic acid precipitation and by ascending paper chromatography using n-butanol:ethanol:ammonium hydroxide (5:1:2;v/v) as solvent system. The results obtained showed that 90% of the radioactivity was protein bound and strongly suggest that this material is thyroglobulin.


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