scholarly journals P30 Mobile health uses in surveillance of tuberculosis medication side effects and beyond-a pilot study

Author(s):  
O Dytko ◽  
M Park ◽  
R Nicholas ◽  
R Akshikar ◽  
OM Kon
2021 ◽  
Author(s):  
Elizabeth Y Wang ◽  
Benjamin N Breyer ◽  
Austin W Lee ◽  
Natalie Rios ◽  
Akinyemi Oni-Orisan ◽  
...  

BACKGROUND Mobile health applications may provide an efficient way for patients with lower urinary tract symptoms (LUTS) to log and communicate symptoms and medication side effects with their clinicians. OBJECTIVE To explore the perceptions of older men with LUTS after using a mobile health application to track their symptoms and tamsulosin side effects. METHODS Structured phone interviews were conducted after a 2-week study piloting the daily use of a mobile application to track severity of patient-selected LUTS and tamsulosin side effects. Quantitative and qualitative data were considered. RESULTS Nineteen (100%) pilot study participants completed the post-study interviews. Most men (68%) reported that the daily questionnaires were the right length, with 32% reporting that the questionnaires were too short. Men with more severe symptoms were less likely to report changes in perception of health or changes in self-management; 47% of men reported improved awareness of symptoms and 5% of men adjusted fluid intake based on the questionnaire. All men were willing to share application data with their clinicians. Thematic analysis of qualitative data yielded 8 themes: 1) orientation (setting up app, format, symptom selection, side effect selection), 2) triggers (routine/habit, symptom timing), 3) daily questionnaire (reporting symptoms, reporting side effects, tailoring), 4) technology literacy, 5) perceptions (awareness, causation/relevance, data quality, convenience, usefulness, other apps), 6) self-management, 7) clinician engagement (communication, efficiency), and 8) improvement (reference materials, flexibility, language, management recommendations, optimize clinician engagement). CONCLUSIONS We assessed the perceptions of men using a mobile health application to monitor and improve management of LUTS and medication side effects. LUTS management may be further optimized by tailoring the mobile application experience to meet patients’ individual needs, such as tracking a greater number of symptoms and integrating the application with clinicians’ visits. Mobile health applications are likely a scalable modality to monitor symptoms and improve care of older men with LUTS. Further study is required to determine the best ways to tailor the mobile application and to communicate data to clinicians or incorporate data into the electronical medical record meaningfully.


BMJ ◽  
2010 ◽  
Vol 341 (sep15 2) ◽  
pp. c4999-c4999

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Claire J. Wiggins ◽  
Susan Y. Chon

As aberrant Notch signaling has been linked to cancerous growth, Notch inhibitors represent a novel category of targeted oncological therapy. Notch pathways in tumor cells may contribute to proliferation or limit apoptosis and differentiation. Healthy skin differentiation and homeostasis are reliant on normal Notch expression, and disruption of this signaling has been implicated in dermatological conditions such as hidradenitis suppurativa, psoriasis, atopic dermatitis, and lichen planus. Here, we describe two cases of patients with cutaneous side effects from Notch inhibitor treatment for adenoid cyst carcinoma (ACC) and review the role of Notch signaling in skin disease. By illuminating connections between medication side effects and disease pathogenesis, our goal is to increase awareness of the cutaneous side effects of Notch inhibitor treatment.


2011 ◽  
Vol 24 (1) ◽  
pp. 159-169 ◽  
Author(s):  
Waleed Fawzi ◽  
Mohamed Yousry Abdel Mohsen ◽  
Abdel Hamid Hashem ◽  
Suaad Moussa ◽  
Elizabeth Coker ◽  
...  

ABSTRACTBackground: Adherence to treatment is a complex and poorly understood phenomenon. This study investigates the relationship between older depressed patients’ adherence to antidepressants and their beliefs about and knowledge of the medication.Methods: Assessment was undertaken of 108 outpatients over the age of 55 years diagnosed with depressive disorder and treated for at least four weeks with antidepressants. Adherence was assessed using two self-report measures: the Medication Adherence Rating Scale (MARS) and a Global Adherence Measure (GAM). Potential predictors of adherence investigated included sociodemographic, medication and illness variables. In addition, 33 carers were interviewed regarding general medication beliefs.Results: 56% of patients reported 80% or higher adherence on the GAM. Sociodemographic variables were not associated with adherence on the MARS. Specific beliefs about medicines, such as “my health depends on antidepressants” (necessity) and being less worried about becoming dependant on antidepressants (concern) were highly correlated with adherence. General beliefs about medicines causing harm or being overprescribed, experiencing medication side-effects and severity of depression also correlated with poor adherence. Linear regression with the MARS as the dependent variable explained 44.3% of the variance and showed adherence to be higher in subjects with healthy specific beliefs who received more information about antidepressants and worse with depression severity and autonomic side-effects.Conclusions: Our findings strongly support a role for specific beliefs about medicines in adherence. Challenging patients’ beliefs, providing information about treatment and discussing side-effects could improve adherence. Poor response to treatment and medication side-effects can indicate poor adherence and should be considered before switching medications.


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