Craniomandibular osteopathy in a golden jackal (Canis aureus)

2019 ◽  
Vol 7 (2) ◽  
pp. e000728
Author(s):  
Darko M Marinković ◽  
Mirjana Lazarević Macanović ◽  
Nikola Krstić ◽  
Duško Ćirović ◽  
Ingrid Gielen
Keyword(s):  
Bone Formation ◽  
Trabecular Bone ◽  
Inflammatory Cells ◽  
Long Bones ◽  
Golden Jackal ◽  
New Bone Formation ◽  
Free Living ◽  
Canis Aureus ◽  
Mandibular Region ◽  
Distal Section

Craniomandibular osteopathy is a rare disorder in dogs, characterised by subperiosteal and extraperiosteal new bone proliferations on the skull, on the mandibles in particular and occasionally on long bones. Data about craniomandibular osteopathy in the golden jackal (Canis aureus) are lacking. This paper describes craniomandibular osteopathy in a seven-month-old animal. The mandibular region and the distal section of the hindlimb were examined radiologically and by CT. Both imaging modalities showed ossifying periosteal deposits localised on the left side of the mandible and irregular periosteal ossifying deposits covering the surface of the crural bones. Histopathology revealed new bone formation in the endosteum, periosteum and trabecular bone of the mandible and in the distal section of the hindlimb, but no inflammatory cells were found. Craniomandibular osteopathy in free-living canids has not yet been reported. However, the macroscopic imaging and histopathological features in this pup were consistent with the disease.

Endosteal New Bone Formation in the Long Bones of Adjuvant Treated Rats

1986 ◽  
Vol 181 (3) ◽  
pp. 331-338 ◽  
Author(s):  
Kunihiko Tomoda ◽  
Mitsuhiko Kitaoka ◽  
Ken-ichi Iyama ◽  
Gentaro Usuku
Keyword(s):  
Bone Formation ◽  
Long Bones ◽  
New Bone Formation

scholarly journals Systemic propolis stimulates new bone formation at the expanded suture

2012 ◽  
Vol 83 (2) ◽  
pp. 286-291 ◽  
Author(s):  
Burcu A. Altan ◽  
Isa M. Kara ◽  
Ruhi Nalcaci ◽  
Fatih Ozan ◽  
Serif M. Erdogan ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Bone Formation ◽  
Inflammatory Cells ◽  
The Other ◽  
New Bone Formation ◽  
Control Groups ◽  
Rat Study ◽  
Expansion Period

ABSTRACT Objective: To investigate the effects of systemically given propolis on the expanded premaxillary suture in a rat study model. Materials and Methods: The 24 rats were randomly divided into three groups—only expansion (OE), expansion plus propolis (PRO), and nonexpansion (control) groups. After the 5-day expansion period was completed, the OE and PRO groups underwent 12 days of mechanical retention. At the end of this period, the animals were euthanatized and their pre-maxillae were dissected and fixed. Histomorphometric examination was performed to determine the number of osteoclasts, osteoblasts, and capillaries as well as the intensity of inflammatory cells and amount of new bone formation. Results: Statistical analysis showed that the intensities of inflammatory cells, number of osteoblasts, and amount of new bone formation were greater in the PRO group than in the other groups. The PRO group also had more osteoclasts and new capillaries. Conclusion: Systemic use of propolis may hasten new bone formation at the expanded suture in rats.

Hypertrophic Osteoarthropathy

2019 ◽  
pp. 361-363
Author(s):  
Noam Belkind ◽  
Adam C. Zoga
Keyword(s):  
Bone Formation ◽  
Imaging Finding ◽  
Appendicular Skeleton ◽  
Hypertrophic Osteoarthropathy ◽  
Long Bones ◽  
New Bone Formation ◽  
Gastrointestinal Polyposis ◽  
Hypertrophic Pulmonary Osteoarthropathy ◽  
Clinical Triad ◽  
Periosteal New Bone Formation

Chapter 69 discusses hypertrophic osteoarthropathy (HOA), which is a clinical triad of periostitis, digital clubbing, and swollen joints. When caused by an underlying pulmonary disease, it is termed hypertrophic pulmonary osteoarthropathy (HPOA). HPOA is most commonly associated with neoplastic lung disease, however, HOA has also been described with cyanotic congenital heart disease, cirrhosis, biliary atresia, inflammatory bowel disease, gastrointestinal polyposis, and thalassemia. The principal imaging finding in HPOA is periostitis and periosteal new bone formation affecting the long bones of the appendicular skeleton in a bilateral and symmetric fashion. Radiographically this manifests as a smooth layer of periosteal new bone formation. Bone scintigraphy demonstrates a characteristic linear radiotracer uptake parallel to the normal cortical bone uptake known as the parallel track or double line sign. MRI similarly demonstrates hyperintense linear periosteal STIR signal that parallels the affected long bones.

LONG BONE INVOLVEMENT IN SICKLE CELL ANEMIA

PEDIATRICS ◽  
1950 ◽  
Vol 5 (2) ◽  
pp. 204-209
Author(s):  
JOHN R. ALMKLOV ◽  
ARILD E. HANSEN ◽  
MARTIN SCHNEIDER
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Pathologic Fracture ◽  
Medullary Cavity ◽  
Long Bone ◽  
Long Bones ◽  
New Bone Formation ◽  
Roentgenographic Examination

Two types of pathologic changes may occur in the long bones of patients with sickle cell anemia. A hyperplastic bone marrow represents the response to continued destruction of erythrocytes and this produces a wide medullary cavity and a thin cortex. The thromboses of vessels in the marrow and bone result in abnormal areas of calcification and new bone formation producing a thick cortex and a small medullary cavity. The findings on roentgenographic examination will depend upon which of the two processes is dominant. A 21 month old Negro infant whose symptoms of sickle cell anemia began at 4 months of age showed typical roentgenographic findings resulting from a hyperplastic marrow. The cortex in the femur had become so thin that a pathologic fracture resulted. This is the first reported instance of the occurrence of a pathologic fracture in sickle cell anemia.

The Evaluation of Alpha Plaster of Paris as a Osteoconductive Material in the Adult Cat Calvarium

1991 ◽  
Vol 252 ◽  
Author(s):  
N. W. Knuckey ◽  
H. Saskin ◽  
R. Yanagasawa ◽  
M. Flanagan
Keyword(s):  
Bone Formation ◽  
Trabecular Bone ◽  
Fibrous Tissue ◽  
New Bone Formation ◽  
Brain Protection ◽  
Plaster Of Paris ◽  
Adult Cat ◽  
Adult Cats ◽  
The Right ◽  
The Ideal

Spontaneous new bone formation does not occur in the adult calvarium. In humans, cranial defects may require repair for brain protection, headaches or cosmetic. Over the years the search for the ideal cranioplasty material to repair such cranial defects has been extensive. We report an evaluation of alpha plaster of paris as an osteoconductive material in a cat craniectomy defect.Adult cats of either sex were anesthetized with ketamine/halothane and a 15mm biparietal craniectomy defect created. The right side was filled with alpha plaster of paris and the left served as a control. There were 4 animals in each time cohort and animals were sacrificed at 6 weeks, 6 or 12 months. The cranium was removed, fixed, stained, histologically studied and analysised for the percentage of trabecular bone formation. At all durations the control defects were bridged by proliferative fibrous tissue membrane and less than 1% trabecular bone. At six weeks the plaster of paris filled defects were either totally or nearly totally replaced by new bone formation. The plaster was completely resorbed. At 6 wks there was 28% trabecular bone which increased to 93% at 52 wks. Our experiments demonstrate the oeteoconductive potential of alpha plaster of paris in the adult calvarium. This material needs to be evaluated in humans to ascertain its potential as a biocompatible cranioplasty material.

scholarly journals Effect of salvianolic acid B on new bone formation in the orthopedically expanded suture:

2020 ◽  
Author(s):  
Emre Kayalar ◽  
Gul Tas Deynek ◽  
Olgu Enis Tok ◽  
Sevim Kucuk
Keyword(s):  
Bone Formation ◽  
Intraperitoneal Administration ◽  
Inflammatory Cells ◽  
Open Loop ◽  
Salvianolic Acid B ◽  
Control Group ◽  
New Bone Formation ◽  
Sprague Dawley ◽  
Salvianolic Acid ◽  
Bone Quantity

ABSTRACT Objectives To determine the effects of Salvianolic acid B (Sal B) on new bone formation in the orthopedically expanded premaxillary sutures in rats. Materials and Methods The sample consisting of Sprague Dawley rats (male, n = 14) was split in half by random selection: the experiment group (Sal B) and the control group. The premaxillary suture of each rat was expanded by bonding an open-loop spring to two maxillary incisors, each end to one tooth. A 5-day expansion period followed by a 12-day retention period was conducted. The 17-day intraperitoneal administration of Sal B was performed daily for the experiment group at a dose of 40 mg/kilo. The trial was completed after sacrificing the rats and dissection of the premaxillae for histological analysis. The amount of new bone, quantity of capillaries and intensity of inflammatory cells were histomorphometrically determined while the quantities of osteoblasts and osteoclasts were determined immunohistochemically. Results The Sal B group was significantly different from the control group and had greater quantities of new bone, capillaries, inflammatory cells, osteoblasts, and osteoclasts. Conclusions Salvianolic acid B displays a positive effect during premaxillary expansion with a greater number of capillaries potentially in association with higher bone formation and improved angiogenesis in rats.

Author response for "Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation"

2020 ◽  
Author(s):  
Gretl Hendrickx ◽  
Verena Fischer ◽  
Astrid Liedert ◽  
Simon von Kroge ◽  
Melanie Haffner‐Luntzer ◽  
...  
Keyword(s):  
Bone Formation ◽  
Trabecular Bone ◽  
Author Response
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