The non-diseased reactor: considerations on the interpretation of screening test results

1979 ◽  
Vol 105 (10) ◽  
pp. 226-228 ◽  
Author(s):  
R. Seiler
Keyword(s):  
2021 ◽  
Vol 104 (2) ◽  
pp. 003685042110261
Author(s):  
Sungwoo Choi ◽  
Hyo Jeong Choi ◽  
Ho Jung Kim

The most common method for SARS-CoV-2 testing is throat or nasal swabbing by real-time reverse transcription polymerase chain reaction (RT-PCR) assay. In South Korea, drive-through swab test is used for screening system and community treatment centers (CTCs), which admit and treat confirmed COVID-19 patients with mild symptoms, are being used. This retrospective study was conducted on patients admitted to a CTC on March 6, 2020. A total of 313 patients were admitted. The nasal and throat swabs were collected from the upper respiratory tract, and a sputum test was performed to obtain lower respiratory samples. The positive rate of the first set of test, sputum test was higher than that of the swab test ( p = 0.011). In the second set of test, 1 week after the first ones, the rate of positive swab tests was relatively high ( p = 0.026). In the first set of test, 66 of 152 (43.4%) patients showed 24-h consecutive negative swab test results, when the sputum test results were considered together, that number fell to 29 patients (19.1%) ( p < 0.001). Also, in the second set of test, 63 of 164 (38.4%) patients met the discharge criteria only when the swab test was considered; that number fell to 30 (18.3%) when the sputum test results were also considered ( p < 0.001). Using the swab test alone is insufficient for screening test and discharge decision. Patients who may have positive result in the sputum test can be missed.


Author(s):  
Bansi Badan Mukhopadhyay ◽  
Himadri Bhattacharjya

Net sensitivity and net specificity have been reviewed from set theoretic approach. With a basic knowledge of set theory one can estimate the net sensitivity and specificity in an easy way in both sequential and simultaneous screening tests. Union, intersection and complementary operations of set theory have been adopted to find out the solutions. 


2020 ◽  
Vol 59 (6) ◽  
pp. 835-837
Author(s):  
Canan Unal ◽  
Atakan Tanacan ◽  
Erdem Fadiloglu ◽  
Oytun Portakal ◽  
M. Sinan Beksac

2013 ◽  
Vol 7 (4) ◽  
pp. 424-427
Author(s):  
Mariana Ribeiro Hur ◽  
Leonardo Caixeta

ABSTRACT Semantic dementia is characterized by fluent, phonologically adequate speech with various anomias and semantic paraphasias. Performance on semantic tasks is well documented in these patients, although little is known regarding performance on more complex language tasks, such as those involving non-literal language (interpretation of metaphors and proverbs and recognition of irony). Objective: To report the investigation of non-literal language in cases of semantic dementia. Methods: Two cases of semantic dementia were investigated for the presence of deficits in non-literal language abilities using the screening test for Alzheimer's disease with proverbs, metaphor test and irony test. Results: Both patients were found to have low performance on the tests applied, particularly for interpretation of proverbs. Conclusion: This poor performance was attributed largely to the characteristic semantic changes of the disease, but some frontal symptoms inherent to other forms of frontotemporal lobar degeneration were also observed which interfered in the testing, such as negativism, reduced attention span, concretism and perseverations.


1971 ◽  
Vol 17 (9) ◽  
pp. 872-874 ◽  
Author(s):  
J I Routh ◽  
R E Bannow

Abstract A simple screening test, sensitive to o-dihydroxyphenyl groups in the urine, was developed for use in monitoring patients with Parkinson's disease who are treated with L-dopa. Compounds measured by this test include dopa, dopamine, 3,4-dihydroxyphenylacetic acid, epinephrine, and norepinephrine. Parallel quantitative experiments, in which ion-exchange chromatography was used, followed by fluorometry and colorimetry, establish the validity of the strip-test results. The test is designed to be used by physician or patient, as well as by clinical laboratory personnel.


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