Evaluation of swinepox virus as a vaccine vector in pigs using an Aujeszky's disease (pseudorabies) virus gene insert coding for glycoproteins gp50 and gp63

1994 ◽  
Vol 134 (1) ◽  
pp. 13-18 ◽  
Author(s):  
M. van der Leek ◽  
J. Feller ◽  
G. Sorensen ◽  
W. Isaacson ◽  
C. Adams ◽  
...  
Keyword(s):  
Pseudorabies Virus ◽  
Vaccine Vector ◽  
Virus Gene ◽  
Aujeszky's Disease ◽  
Aujeszky’S Disease ◽  
Swinepox Virus

Recent developments in latency and recombination of Aujeszky's disease (pseudorabies) virus

1997 ◽  
Vol 55 (1-4) ◽  
pp. 13-27 ◽  
Author(s):  
Roger K. Maes ◽  
Michael D. Sussman ◽  
Aivars Vilnis ◽  
Brad J. Thacker
Keyword(s):  
Pseudorabies Virus ◽  
Aujeszky's Disease ◽  
Aujeszky’S Disease ◽  
Recent Developments

scholarly journals The Attenuated Pseudorabies Virus Vaccine Strain Bartha K61: A Brief Review on the Knowledge Gathered during 60 Years of Research

Pathogens ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 897
Author(s):  
Jonas L. Delva ◽  
Hans J. Nauwynck ◽  
Thomas C. Mettenleiter ◽  
Herman W. Favoreel
Keyword(s):  
Vaccine Strain ◽  
Pseudorabies Virus ◽  
Economic Losses ◽  
Vaccination Programs ◽  
Live Vaccines ◽  
Vector Vaccine ◽  
Short Summary ◽  
Aujeszky's Disease ◽  
Aujeszky’S Disease ◽  
Disease Epidemics

Pseudorabies virus (PRV) is a member of the alphaherpesvirus subfamily of the herpesviruses and is the causative agent of Aujeszky’s disease in pigs, causing respiratory, neurological, and reproductive symptoms. Given the heavy economic losses associated with Aujeszky’s disease epidemics, great efforts were made to develop efficacious vaccines. One of the best modified live vaccines to this day is the attenuated Bartha K61 strain. The use of this vaccine in extensive vaccination programs worldwide has assisted considerably in the eradication of PRV from the domesticated pig population in numerous countries. The Bartha K61 strain was described in 1961 by Adorján Bartha in Budapest and was obtained by serial passaging in different cell cultures. Ever since, it has been intensively studied by several research groups, for example, to explore its efficacy as a vaccine strain, to molecularly and mechanistically explain its attenuation, and to use it as a retrograde neuronal tracer and as a vector vaccine. Given that the Bartha K61 vaccine strain celebrates its 60th birthday in 2021 with no sign of retirement, this review provides a short summary of the knowledge on its origin, characteristics, and use as a molecular tool and as a vaccine.

Efficacy of Various Non-Oily Adjuvants in Immunization Against the Aujeszky's Disease (Pseudorabies) Virus

1993 ◽  
Vol 40 (1-10) ◽  
pp. 353-365 ◽  
Author(s):  
E. Puentes ◽  
E. Cancio ◽  
A. Eiras ◽  
M. V. Nores ◽  
A. Aguilera ◽  
...  
Keyword(s):  
Pseudorabies Virus ◽  
Aujeszky's Disease ◽  
Aujeszky’S Disease

scholarly journals Aujeszky’s Disease in South-Italian Wild Boars (Sus Scrofa): A Serological Survey

Animals ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3298
Author(s):  
Gianmarco Ferrara ◽  
Consiglia Longobardi ◽  
Filomena D’Ambrosi ◽  
Maria Grazia Amoroso ◽  
Nicola D’Alessio ◽  
...  
Keyword(s):  
Wild Boar ◽  
Sus Scrofa ◽  
Pseudorabies Virus ◽  
Viral Disease ◽  
Serum Samples ◽  
Hunting Season ◽  
Campania Region ◽  
Wild Boars ◽  
Aujeszky's Disease ◽  
Aujeszky’S Disease

Aujeszky’s disease (AD, pseudorabies) is a viral disease of suids caused by Suid Herpesvirus 1 (SHV-1) also referred as Aujeszky’s disease virus (ADV) or Pseudorabies virus (ADV). Domestic pig and Wild boar (Sus scrofa) are the natural host, but many species can be infected with ADV. The aim of our study was to evaluate seroprevalence of AD in wild boar hunted in the Campania Region, during the 2016–2017 hunting season. A total of 503 serum samples from wild boars hunted in the provinces of Campania Region (Southern Italy) were collected and were tested for antibody against ADV using an AD, blocking ELISA assay. A Seroprevalence of 23.85% (120/503, 95% Confidence Interval (CI): 20.15–27.55) was found. Gender was not significantly associated with of ADV seropositivity (p > 0.05), while the presence of ADV antibodies was statistically associated with age (>36-month, p < 0.0001) and location (Avellino, p = 0.0161). Our prevalence values are like those obtained in 2010 in our laboratory (30.7%), demonstrating a constant circulation of ADV in the area.

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