AN ANALYSIS OF XANTHINE DEHYDROGENASE NEGATIVE MUTANTS OF THE ROSY LOCUS IN DROSOPHILA MELANOGASTER
1979 ◽
Vol 21
(3)
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pp. 379-389
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Eighteen alleles of the rosy locus in Drosophila melanogaster were characterized to identify putative nonsense mutants. Seven alleles exhibited no evidence of intragenic complementation, no evidence of immunological cross-reactivity to antibodies elicited by wild type xanthine dehydrogenase (XDH), and of course were completely deficient in measurable XDH activity. It is possible that one or more of these highly negative ry alleles are nonsense mutants. The remaining eleven ry alleles code for XDH molecules that retain some antigenic similarities to the wild type enzyme as assessed by immunoelectrophoresis and six of these eleven were capable of intragenic complementation.
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1988 ◽
Vol 89
(2)
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pp. 263-269
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1976 ◽
Vol 62
(3)
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pp. 591-600
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1982 ◽
Vol 24
(1)
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pp. 11-17
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1979 ◽
Vol 21
(4)
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pp. 457-471
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