Effect of Exercise Intensity on Free Tryptophan to Branched-Chain Amino Acids Ratio and Plasma Prolactin During Endurance Exercise

1997 ◽  
Vol 22 (3) ◽  
pp. 280-291 ◽  
Author(s):  
Heiko K. Strüder ◽  
Wildor Hollmann ◽  
Petra Platen ◽  
Ronny Wöstmann ◽  
Alexander Ferrauti ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Free Fatty Acids ◽  
Endurance Exercise ◽  
Exercise Duration ◽  
Cycle Ergometer ◽  
Plasma Prolactin ◽  
Free Tryptophan ◽  
Energy Bar ◽  
Intensity Of Exercise

The potential of exercise-induced changes in peripheral amino acids to alter blood prolactin levels through a seratonergic system modification was investigated in 8 male athletes. In two trials, subjects (N = 8) exercised on a cycle ergometer for 5 hr. The intensity of exercise corresponded to 55% VO2max (T55) or 75% VO2max (T75) respectively. In each trial, each subject received a 25-g energy bar (111 kcal) every 60 min, as well as 300 ml of a 6% carbohydrate solution (90 kcal) every 30 min of exercise duration. Plasma glucose and insulin declined (p ≤.05) in both trials during exercise. Ammonia was augmented (p ≤.05) above the baseline concentration after 120 min in both trials. During the last 2 hr of exercise, plasma free fatty acids were higher (p ≤.05) in T75, than in T55. During this time, the plasma free TRP/BCAA ratio was also augmented (p ≤.05) in T75 while no change was induced in T55. Plasma prolactin did not change in T55, while an increase (p ≤.05) was found in T75. The findings may further support the hypothesis that during endurance exercise changes in peripheral amino acid concentration may influence prolactin response via serotonergic system modifications. Key words: blood-brain barrier, serotonin, neuroendocrine system, free fatty acids, ammonia

Metabolic Response to Provision of Mixed Protein-Carbohydrate Supplementation during Endurance Exercise

2002 ◽  
Vol 12 (4) ◽  
pp. 384-397 ◽  
Author(s):  
Sharon L. Miller ◽  
Carl M. Maresh ◽  
Lawrence E. Armstrong ◽  
Cara B. Ebbeling ◽  
Shannon Lennon ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Growth Hormone ◽  
Free Fatty Acids ◽  
Endurance Exercise ◽  
Metabolic Response ◽  
Essential Amino Acids ◽  
Nutritional Supplementation ◽  
Post Exercise ◽  
Branched Chain

The interaction of substrates and hormones in response to ingestion of intact proteins during endurance exercise is unknown. This study characterized substrate and hormone responses to supplementation during endurance exercise. Nine male runners participated in 3 trials in which a non-fat (MILK), carbohydrate (CHO), or placebo (PLA) drink was consumed during a 2-hour treadmill >· run at 65% V̇O2max. Circulating levels of insulin, glucagon, epinephrine, norepi-nephrine, growth hormone, testosterone, and cortisol were measured. Plasma substrates included glucose, lactate, free fatty acids, and select amino acids. Except for insulin and cortisol, hormones increased with exercise. While post-exercise insulin concentrations declined similarly in all 3 trials, the glucagon increase was greatest following MILK consumption. CHO blunted the post-exercise increase in growth hormone compared to levels in MILK. Free fatty acids and plasma amino acids also were responsive to nutritional supplementation with both CHO and MILK attenuating the rise in free fatty acids compared to the increase observed in PLA. Correspondingly, respiratory exchange ratio increased during CHO. Essential amino acids increased significantly only after MILK and were either unchanged or decreased in CHO. PLA was characterized by a decrease in branched-chain amino acid concentrations. Modest nutritional supplementation in this study altered the endocrine response as well as substrate availability and utilization following and during an endurance run, respectively.

1010-P: Effects of MEDI0382, an Oxyntomodulin-Like Peptide with Targeted GLP-1/Glucagon Receptor Activity, on Amino Acids, Ketones, and Free Fatty Acids

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1010-P
Author(s):  
VICTORIA E. PARKER ◽  
DARREN ROBERTSON ◽  
TAO WANG ◽  
DAVID C. HORNIGOLD ◽  
MAXIMILIAN G. POSCH ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Free Fatty Acids ◽  
Receptor Activity ◽  
Glucagon Receptor

The Metabolic Response of Glycogen and Free Fatty Acids to Endurance Exercise

2017 ◽  
Vol 5 (1) ◽  
pp. 68-75
Author(s):  
Piero Ipata ◽  
Francesco Balestri ◽  
Rossana Pesi
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Endurance Exercise ◽  
Metabolic Response

Hydrocarbons, free fatty acids, and amino acids of sclerotia of Sclerotinia sclerotiorum

1970 ◽  
Vol 75 (1) ◽  
pp. 59-66 ◽  
Author(s):  
John D. Weete ◽  
D. J. Weber ◽  
Duane Tourneau
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Free Fatty Acids ◽  
Sclerotinia Sclerotiorum

scholarly journals Altitudinal Variation of Metabolites, Mineral Elements and Antioxidant Activities of Rhodiola crenulata (Hook.f. & Thomson) H.Ohba

Molecules ◽  
2021 ◽  
Vol 26 (23) ◽  
pp. 7383
Author(s):  
Tingting Dong ◽  
Yueqi Sha ◽  
Hairong Liu ◽  
Liwei Sun
Keyword(s):  
Amino Acids ◽  
Fatty Acids ◽  
Ascorbic Acid ◽  
Free Fatty Acids ◽  
High Altitude ◽  
Antioxidant Activities ◽  
Shikimic Acid ◽  
Ascorbic Acid Content ◽  
Phenolic Components ◽  
Rhodiola Crenulata

Rhodiolacrenulata (Hook.f. & Thomson) H.Ohba is an alpine medicinal plant that can survive in extreme high altitude environments. However, its changes to extreme high altitude are not yet clear. In this study, the response of Rhodiola crenulata to differences in altitude gradients was investigated through chemical, ICP-MS and metabolomic methods. A targeted study of Rhodiola crenulata growing at three vertical altitudes revealed that the contents of seven elements Ca, Sr, B, Mn, Ni, Cu, and Cd, the phenolic components, the ascorbic acid, the ascorbic acid/dehydroascorbate ratio, and the antioxidant capacity were positively correlated with altitude, while the opposite was true for total ascorbic acid content. Furthermore, 1165 metabolites were identified: flavonoids (200), gallic acids (30), phenylpropanoids (237), amino acids (100), free fatty acids and glycerides (56), nucleotides (60), as well as other metabolites (482). The differential metabolite and biomarker analyses suggested that, with an increasing altitude: (1) the shikimic acid-phenylalanine-phenylpropanoids-flavonoids pathway was enhanced, with phenylpropanoids upregulating biomarkers much more than flavonoids; phenylpropanes and phenylmethanes upregulated, and phenylethanes downregulated; the upregulation of quercetin was especially significant in flavonoids; upregulation of condensed tannins and downregulation of hydrolyzed tannins; upregulation of shikimic acids and amino acids including phenylalanine. (2) significant upregulation of free fatty acids and downregulation of glycerides; and (3) upregulation of adenosine phosphates. Our findings provide new insights on the responses of Rhodiola crenulata to extreme high altitude adversity.

Influence Of Branched-chain Aminoacids (BCAA) Supplementation On Free Fatty Acids Oxidation During Endurance Exercise After Muscle Glycogen Depletion

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S349
Author(s):  
Thomas B. Adolpho ◽  
Patr??cia Lopes Campos ◽  
Bruno Gualano ◽  
Josilene Carla Gomes ◽  
Fernanda Baeza Scagliusi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Endurance Exercise ◽  
Muscle Glycogen ◽  
Glycogen Depletion ◽  
Branched Chain

Influence Of Branched-chain Aminoacids (BCAA) Supplementation On Free Fatty Acids Oxidation During Endurance Exercise After Muscle Glycogen Depletion

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S349
Author(s):  
Thomas B. Adolpho ◽  
Patrícia Lopes Campos ◽  
Bruno Gualano ◽  
Josilene Carla Gomes ◽  
Fernanda Baeza Scagliusi ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Endurance Exercise ◽  
Muscle Glycogen ◽  
Glycogen Depletion ◽  
Branched Chain
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