HAEMATOLOGIC CHANGES CAUSED BY HYPOTHERMIA IN HAMSTERS AND RATS

1962 ◽  
Vol 40 (5) ◽  
pp. 591-595 ◽  
Author(s):  
T. Orme ◽  
J. R. Beaton ◽  
J. Laufer

As a consequence of hypothermia (15 °C rectal temperature) in the rat and the hamster, there are increases in red cell fragility and in blood clotting time and a decrease in prothrombin time. In the hypothermic hamster there are significant increases in haemoglobin and erythrocyte count but mean corpuscular volume, mean corpuscular haemoglobin content, and serum protein levels are not altered. These findings indicate that, unlike the hypothermic rat, the hypothermic hamster has an increased haematocrit as a consequence of increased release or decreased destruction of erythrocytes rather than as a consequence of increased cell size and decreased plasma volume. Hypothermia causes a marked leukopenia in both the hamster and the rat but causes an alteration in the relative numbers of lymphocytes and neutrophiles only in the rat.

1962 ◽  
Vol 40 (1) ◽  
pp. 591-595
Author(s):  
T. Orme ◽  
J. R. Beaton ◽  
J. Laufer

As a consequence of hypothermia (15 °C rectal temperature) in the rat and the hamster, there are increases in red cell fragility and in blood clotting time and a decrease in prothrombin time. In the hypothermic hamster there are significant increases in haemoglobin and erythrocyte count but mean corpuscular volume, mean corpuscular haemoglobin content, and serum protein levels are not altered. These findings indicate that, unlike the hypothermic rat, the hypothermic hamster has an increased haematocrit as a consequence of increased release or decreased destruction of erythrocytes rather than as a consequence of increased cell size and decreased plasma volume. Hypothermia causes a marked leukopenia in both the hamster and the rat but causes an alteration in the relative numbers of lymphocytes and neutrophiles only in the rat.


2006 ◽  
Vol 75 (2) ◽  
pp. 203-207 ◽  
Author(s):  
L. Vetešník ◽  
K. Halačka ◽  
V. Lusková ◽  
S. Lusk

Haematological analysis was performed on 27 adult specimens of Carassius auratus irrespective of sex in 2003 and on 32 juveniles of distinguished sex in 2004. In this study we found that the ploidy level affected significantly (p < 0.01) the values of the erythrocyte count, mean corpuscular volume and mean corpuscular haemoglobin. Although we did not prove any significant effect of sex in juvenile diploids of C. auratus on the values of erythrocyte profile, the erythrocyte count, haematocrit value and haemoglobin content value were higher for males than for females. The erythrocyte count decreased significantly (p < 0.01) with increasing ploidy level. The index of haemoglobin content followed the same trend of a decreasing mean value with increasing ploidy level. Mean corpuscular volume and mean corpuscular haemoglobin increased with the increasing ploidy level (p < 0.01). Haematocrit value and mean corpuscular haemoglobin concentration did not significantly differ from the point of view of the ploidy level.


Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1017
Author(s):  
Thomas Müller ◽  
Lutz Lohse ◽  
Andreas Blodau ◽  
Katja Frommholz

Background: Vitamin D has a steroid- and an anabolic-resembling chemical structure. Vitamin D is essential for many processes in the human body after hydroxylation. Aims of the Study: To investigate the impact of 25-hydroxy-vitamin D plasma concentrations on the blood parameters number of erythrocytes, hematocrit, mean corpuscular hemoglobin and mean corpuscular volume. Methods: Serial assessments were done in 290 patients with multiple sclerosis and repeated after a mean interval of 245 days. A recommendation for vitamin D supplementation was given in case of a concentration lower than 20 ng/mL combined with a prescription of a formulation containing vitamin D but not vitamin K. Results: There was a fall of vitamin D in 119 subjects and a rise in 164, while no change appeared in 7 participants. When vitamin D values went down between both assessments moments, the computed increase of mean corpuscular haemoglobin was significantly lower compared with the rise of mean corpuscular haemoglobin associated with a vitamin D elevation. When vitamin D declined, the computed fall of mean corpuscular volume fall was significantly lower compared with the decrease of mean corpuscular volume, when vitamin D rose. Positive correlations were found between differences of vitamin D and mean corpuscular haemoglobin, respectively mean corpuscular volume. Inverse relations appeared between disparities of vitamin D and erythrocytes, respectively haematocrit. Conclusions: The elevation of vitamin D plasma levels provides enhanced preconditions for a better tissue oxygenation on a cellular level.


Author(s):  
I Gede Agus Eva Prawira Adinata ◽  
Ni Ketut Suwiti ◽  
Anak Agung Sagung Kendran

Telah dilakukan penelitian untuk mengetahui nilai hematologi MCHC (Mean Corpuscular Hemoglobin Concentration), MCV (Mean Corpuscular Volume) dan MCH (Mean Corpuscular Haemoglobin) darah sapi bali yang dipelihara berbasis organik. Sistem pemeliharaan berbasis organik adalah manajemen pemberian pakan yang berasal dari lingkungan serta tidak menggunakan pestisida atau zat kimia lainnya. Nilai MCV, MCH dan MCHC darah sapi bali diukur dengan Veterinary hematology analyzer. Hasil penelitian menunjukan, nilai dari MCHC sebesar 39,17%/dl, MCV sebesar 48,44 fl dan nilai dari MCH sebesar 18,69pg. Dapat disimpulkan rerata nilai tersebut masih dalam batas normal nilai indeks eritrosit sapi pada umumnya.


2006 ◽  
Vol 116 (3) ◽  
pp. 223-225 ◽  
Author(s):  
Manju Mamtani ◽  
Anil Jawahirani ◽  
Vinky Rughwani ◽  
Kishor Das ◽  
Hemant Kulkarni

Author(s):  
S. D. Agokeng ◽  
A. L. Njunda ◽  
C. T. Tayou ◽  
C. N. J. Assob

A Cross sectional multicentre study was carried out to determine the prevalence of Iron deficiency (ID) and Iron deficiency anaemia (IDA) in children using Ferritin and full blood count. Full blood count was done with Mindray Bc-2800 and Ferritin test with Enzyme Linked Immuno-Sorbent Assay. Authorization was granted by Cameroonian national Ethical Committee. Data were analysed using Statistical Package of Social Sciences 21.0 significant results were considered for P< 0.05. ID varied from 4.2% to 9.6% for cut-offs of 30 and 50μg/L. IDA ranged from 4.2 to 8.5% at these 2 cut-offs. Considering red cells indices, Mean Corpuscular Volume and Mean Corpuscular Haemoglobin blood count currently used should be interpreted cautiously as only Mean Corpuscular Volume and Mean Corpuscular Haemoglobin corroborate with a Ferritin level lower than 30 μg/L.


2020 ◽  
Vol 24 (9) ◽  
pp. 1555-1561
Author(s):  
O.O. Egbewande

Effect of alum-treated groundnut (Arachis hypogea) shell (ATGNS) meal was studied on the blood chemistry and carcass characteristics of broiler chickens. Two hundred and forty (240) day-old broiler chicks of Anak strain were used for the study in a completely randomized design for eight weeks. The chicks were allotted into six groups of forty chicks each and further divided into four replicates of ten chicks each.Groundnut shell (GNS) was processed by soaking it in water containing alum in ratio 1kg of groundnut shell: 15 litre of water: 600g of alum for three, four, five and six days. Wheat offal was included at 10% in T1 as positive control, 4% wheat offal and 6% untreated groundnut shell (GNS) in T2 as negative control, and 4% wheat offal with 6% treated GNS in treatments 3, 4, 5 and 6 at three days, four day, five days and six days of processing respectively. Results on haematological parameters were not significantly (p>0.05) different except mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH). Birds in T5 performed better than others in mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) with highestvalues of 123.83% and 41.93pg respectively, while birds in T3 had the lowest values of 115.28% and 39.05pg in the two parameters respectively. There were significant (p<0.05) differences in serum total protein, albumin and globulin, while other parameters measured showed no significant (p>0.05) differences in serum biochemical studies. Birds fed treatment 1 (T1) had the highest values of 3.95 and 2.72g/dl in total protein and globulin respectively, while the lowest values 2.55 and 0.97g/dl were obtained from birds in T6 respectively. Cut-up parts showed significant (p<0.05) differences in head, neck, back and thigh across treatment means with the exception of other parameters considered. The live weights of birdson processed groundnut shell meal, although not significantly (p>0.05) different, were better (p<0.05) than those on untreated groundnut shell meal (T2). Birds in T6 had the highest values (2.95, 4.60 and 12.53%) in head, neck and thigh respectively. The highest weight (18.02%) of back was recorded in T1. Birds in T4 had the highest values of 19.60 and 4.20% in breast muscle and shank respectively, while those in T3 recorded the lowest (14.65%) in breast muscle, and those in T2 had the lowest (3.56%) in shank. The results in conclusion, showed that alum-treated groundnut shell(ATGNS) could replace wheat offal at 6% level of inclusion by improving carcass yield as well as maintainingblood profile of broiler chickens. Keywords: Groundnut shell, alum, blood chemistry, carcass, broiler


2000 ◽  
Vol 6 (2-3) ◽  
pp. 233-237
Author(s):  
A. A. Al Shakour ◽  
A. A. Al Suhail

The proportion of sickle haemoglobin [HbS] was determined in 170 sickle-cell-trait individuals; 75 [44.1%] individuals had HbS% > 38%, 54 [31.8%] had HbS% between 31% and 38% and 41 [24.1%] had HbS% < 31%. There was positive correlation between HbS% and haemoglobin concentration, packed cell volume, mean corpuscular haemoglobin, mean corpuscular volume and target cell percentage. Multiple regression analysis indicated that measurement of haemoglobin concentration, mean corpuscular haemoglobin and target cell percentage could be used to predict the HbS%


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