Effect of substituents on absorption and fluorescence properties of pyrazolo[3,4-b]pyrrolo[2,3-d]pyridines

2008 ◽  
Vol 86 (11) ◽  
pp. 1070-1076 ◽  
Author(s):  
Bhausaheb K Ghotekar ◽  
Muddassar A Kazi ◽  
Madhukar N Jachak ◽  
Raghunath B Toche
Keyword(s):  
Good Yield ◽  
Substituent Effect ◽  
Photophysical Properties ◽  
Fluorescence Properties ◽  
Absorption And Emission ◽  
Effect Of Substituents ◽  
Convenient Route

A convenient route was successfully developed for the synthesis of novel heterocycles such as pyrazolo[3,4-b]pyrrolo[2,3-d]pyridines (PPP) from pyrazolo[3,4-b]pyridines in good yield. The PPP derivatives synthesized were further studied for their photophysical properties, and it was observed that absorption and emission λmax changed, owing to the substituent effect at 4 positions. These compounds were obtained from highly reactive starting materials, 5-aminopyrazoles and α-acetyl γ-butyrolactone.Key words: α-acetyl γ-butyrolactone, pyrazolo[3,4-b]pyrrolo[2,3-d] pyridine, absorption, emission, fluorescence.

Fluorescence properties of dienone derivatives and solvent effects on their fluorescence absorption and emission

2015 ◽  
Vol 118 (1) ◽  
pp. 67-72 ◽  
Author(s):  
P. Ruanwas ◽  
S. Chantrapromma ◽  
C. Karalai ◽  
C. S. Chidan Kumar
Keyword(s):  
Solvent Effects ◽  
Fluorescence Properties ◽  
Absorption And Emission

Extended fluorescent uridine analogues: synthesis, photophysical properties and selective interaction with BSA protein

2020 ◽  
Vol 44 (34) ◽  
pp. 14744-14754 ◽  
Author(s):  
Ajaykumar V. Ardhapure ◽  
Vijay Gayakhe ◽  
Shatrughn Bhilare ◽  
Anant R. Kapdi ◽  
Subhendu Sekhar Bag ◽  
...  
Keyword(s):  
Photophysical Properties ◽  
Fluorescence Properties ◽  
Selective Interaction ◽  
Fluorescent Nucleosides

The improvement in fluorescence properties of 2′-deoxyuridine was made possible by the introduction of (hetero)aromatic moieties at the C–5 position of uridine with alkenyl/phenyl/styryl linkers to create a library of useful fluorescent nucleosides.

Substituent Effect on the Structure and Photophysical Properties of Phenylamino- and Pyridylamino-2,1,3-Benzothiadiazoles

2019 ◽  
Vol 60 (10) ◽  
pp. 1670-1680
Author(s):  
T. S. Sukhikh ◽  
R. M. Khisamov ◽  
D. A. Bashirov ◽  
L. M. Kovtunova ◽  
N. V. Kuratieva ◽  
...  
Keyword(s):  
Substituent Effect ◽  
Photophysical Properties

scholarly journals Photophysical properties of pyrrolocytosine, a cytosine fluorescent base analogue

2016 ◽  
Vol 18 (30) ◽  
pp. 20189-20198 ◽  
Author(s):  
Quynh L. Nguyen ◽  
Vincent A. Spata ◽  
Spiridoula Matsika
Keyword(s):  
Hydrogen Bonding ◽  
Ab Initio ◽  
Photophysical Properties ◽  
Fluorescence Properties ◽  
Water Molecules ◽  
Pi Stacking ◽  
High Level

The fluorescence properties of pyrrolocytosine, a cytosine analogue, are investigated using high level ab initio methods, and they are found to be affected by hydrogen bonding to water molecules, as well as by pi-stacking with guanine.

scholarly journals Unsymmetrically functionalized 5,5″-diaryl- and 5,6,5″-triaryl-2,2′:6′,2″-terpyridines: an efficient synthetic route and photophysical properties

2017 ◽  
Vol 95 (8) ◽  
pp. 851-857 ◽  
Author(s):  
Alexey P. Krinochkin ◽  
Dmitry S. Kopchuk ◽  
Albert F. Khasanov ◽  
Nikolay V. Chepchugov ◽  
Igor S. Kovalev ◽  
...  
Keyword(s):  
Organic Solvents ◽  
Photophysical Properties ◽  
Emission Spectra ◽  
Side Chain ◽  
Synthetic Route ◽  
Absorption And Emission ◽  
Efficient Approach ◽  
Absorption And Emission Spectra ◽  
Acetonitrile Solutions ◽  
Intense Emission

An efficient approach for the synthesis of 5,5″- or 5,6,5″-aryl substituted 2,2′:6′,2″-terpyridines, bearing an anneleted cyclopentene unit in one of the side-chain pyridine rings for the improved solubility in organic solvents, via their 1,2,4-triazine analogues has been developed. By using this approach, various aromatic substituents were introduced in the 2,2′:6′,2″-terpyridine core. Depending on the nature of the aromatic substituents, the obtained terpyridines exhibited an intense emission in a range of ca. 344–394 nm in acetonitrile solutions. For the most representative compounds, pronounced bathochromic shifts in both absorption and emission spectra were observed compared with previously reported substituted terpyridines.

Photophysical Properties of Carbazole Derivative DPSPC Doped Composite Glass

2011 ◽  
Vol 239-242 ◽  
pp. 1006-1009
Author(s):  
Yun Long Deng ◽  
Yun Hui Sun ◽  
Du Xia Cao ◽  
Ying Chen ◽  
Zhi Qiang Liu
Keyword(s):  
Fluorescence Quenching ◽  
Methyl Methacrylate ◽  
Photophysical Properties ◽  
Sol Gel ◽  
Organic Dye ◽  
Fluorescence Properties ◽  
Donor Group ◽  
Carbazole Derivative ◽  
Composite Glass ◽  
Gel Glasses

A D-π-D type of organic dye 2,7-di[4-(N,N-diphenylamino)styryl]-9-n-pentyl-9H- carbazole (DPSPC) with diphenylamine as donor group and styrene-carbazole-styrene as conjugation bridge has been synthesized. The photophysical properties of the dye in different solvents and poly methyl methacrylate/organic modified sol-gel glasses are researched. The results indicate that the fluorescence properties of the organic dye in composite glass increase relative to that in solvents and there are no fluorescence quenching in high doped concentration in composite glass matrixes. The dye has higher stability in the composite glass than that in solution.

scholarly journals Tritolylporphyrin dimer as a new potent hydrophobic sensitizer for photodynamic therapy of melanoma.

2001 ◽  
Vol 48 (1) ◽  
pp. 277-282 ◽  
Author(s):  
A Drzewiecka ◽  
K Urbańska ◽  
Z Matuszak ◽  
M Pineiro ◽  
L G Arnaut ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Quantum Yield ◽  
Singlet Oxygen ◽  
Biological Effect ◽  
Photophysical Properties ◽  
Red Light ◽  
Human Melanoma ◽  
Oxygen Production ◽  
Absorption And Emission ◽  
Emission Properties

We report the synthesis, photochemical and photophysical properties and preliminary studies on biological effect of a new tritolylporphyrin dimer (T-D). Absorption and emission properties of T-D suggest its possible use in photodynamic therapy. T-D is capable of singlet oxygen production with 0.8 quantum yield. It also has a high photostability. The photodynamic properties of the dimer were examined following the growth of SKMEL 188 (human melanoma) cells irradiated with red light (cut off < 630 nm). The surviving fraction of the cells decreased about 3-fold (vs. non-irradiated cells) for an 81 J/cm dose. Our results suggest that tritolylporphyrine dimer T-D may be an interesting hydrophobic sensitizer for photodynamic therapy.

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