The Preparation and Properties of Some Cyclic β-Diketone Diimines

The condensation reaction between a series of aliphatic diamines and a series of five- and six-membered cyclic β-diketones to form Schiff bases was investigated. Mass spectral data show that reaction occurred on the side-chain carbonyl except where steric hindrance forced condensation to occur on the ring carbonyl. N.m.r. studies show that these Schiff bases exist primarily in the ketamine form in solution, irrespective of the solvent. I.r. data confirm this. The preparation of a number of Cu(II) and Ni(II) complexes from some of the ligands is also described.

Download Full-text

Metal complexes of Schiff bases derived from dicinnamoylmethane and aliphatic diamines

Journal of the Serbian Chemical Society ◽

10.2298/jsc0804423k ◽

2008 ◽

Vol 73 (4) ◽

pp. 423-429 ◽

Cited By ~ 1

Author(s):

K. Krishnankutty ◽

P. Sayudevi ◽

Basheer Ummathur

Keyword(s):

Metal Complexes ◽

Spectral Data ◽

Schiff Bases ◽

1H Nmr ◽

Mass Spectral Data ◽

Mass Spectral ◽

Aliphatic Diamines ◽

Hydrogen Bonded

Two new Schiff bases containing olefinic linkages have been synthesized by condensing aliphatic diamines with dicinnamoylmethane under specified conditions. The existence of these compounds predominantly in the intramolecularly hydrogen bonded keto-enamine form was well demonstrated by their IR, 1H-NMR and mass spectral data. Dibasic tetradentate N2O2 coordination of the compounds in their [ML] complexes (M = Ni(II), Cu(II) and Zn(II)) was established on the basis of analytical and spectral data.

Download Full-text

Friedel–Crafts alkylation of benzene with 1,1-d2-1-chloropropane

Canadian Journal of Chemistry ◽

10.1139/v70-138 ◽

1970 ◽

Vol 48 (5) ◽

pp. 858-862 ◽

Cited By ~ 2

Author(s):

C. C. Lee ◽

D. J. Woodcock

Keyword(s):

Mass Spectrometry ◽

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Spectral Data ◽

Reaction Medium ◽

Side Chain ◽

Mass Spectral Data ◽

Mass Spectral ◽

Alkylation Of Benzene ◽

Nuclear Magnetic

The AlCl3 catalyzed reaction of 1,1-d2-1-chloropropane with benzene was carried out in excess benzene at about 5° or in 1,2,4-trichlorobenzene as solvent at 0°. The products, n-propylbenzene and isopropylbenzene, were examined by nuclear magnetic resonance and mass spectrometry. The results indicated only very minor amounts of isotope position scrambling in the propyl side chain, suggesting no major involvement of protonated cyclopropane intermediates in the reaction. The mass spectral data, however, demonstrated that the products are quite labile in the reaction medium, with extensive intermolecular hydride and deuteride transfers taking place.

Download Full-text

Green Synthetic Protocol for (E)-1-Aryl-3-(2-morpholinoquinolin- 3-yl)prop-2-en-1-ones and Their Antimicrobial Activity

Asian Journal of Chemistry ◽

10.14233/ajchem.2019.21968 ◽

2019 ◽

Vol 31 (9) ◽

pp. 1895-1898

Author(s):

Relangi Siva Subrahmanyam ◽

Venkateswara Rao Anna

Keyword(s):

Antimicrobial Activity ◽

Spectral Data ◽

1H Nmr ◽

13C Nmr ◽

Mass Spectral Data ◽

In Vitro Antimicrobial Activity ◽

Mass Spectral ◽

Fungal Organisms

We report here an easy, efficient and green synthetic protocol for the (E)-1-aryl-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones by the Claisen-Schmidt condensation of 2-morpholinoquinoline-3-carbaldehyde and different substituted acetophenones by using 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim)BF4. The compounds were characterized by using 1H NMR, 13C NMR and mass spectral data and screened there in vitro antimicrobial activity against different bacterial and fungal organisms.

Download Full-text

N-(2-(1H-Indol-3-yl)ethyl)-2-(6-methoxynaphthalen-2-yl)propanamide

Molbank ◽

10.3390/m1187 ◽

2021 ◽

Vol 2021 (1) ◽

pp. M1187

Author(s):

Stanimir Manolov ◽

Iliyan Ivanov ◽

Dimitar Bojilov

Keyword(s):

Spectral Data ◽

13C Nmr ◽

Title Compound ◽

High Yield ◽

Mass Spectral Data ◽

Mass Spectral

The title compound was obtained in high yield in the reaction between tryptamine and naproxen. The newly synthesized naproxen derivative was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

Download Full-text

(1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-Methyl-1H-tetrazol-5-yl)thio)Cyclopent-2-en-1-ol

Molbank ◽

10.3390/m1199 ◽

2021 ◽

Vol 2021 (2) ◽

pp. M1199

Author(s):

Milene A. G. Fortunato ◽

Filipa Siopa ◽

Carlos A. M. Afonso

Keyword(s):

Spectral Data ◽

13C Nmr ◽

Ring Opening ◽

Environmentally Friendly ◽

Mass Spectral Data ◽

Mass Spectral ◽

Excellent Yield ◽

Ring Opening Reaction ◽

Nucleophilic Ring Opening

Using environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data.

Download Full-text