The application of resonant ion ejection to quadrupole ion storage mass spectrometry: a study of ion/molecule reactions in the QUISTOR

1979 ◽  
Vol 57 (16) ◽  
pp. 2108-2113 ◽  
Author(s):  
Mary Alison Armitage ◽  
John Edward Fulford ◽  
Duong-Nhu- Hoa ◽  
Richard James Hughes ◽  
Raymond Evans March
Keyword(s):  
Quadrupole Mass ◽  
Ion Chemistry ◽  
Mass Filter ◽  
Chemical Systems ◽  
Ion Molecule Reactions ◽  
Resonant Ejection ◽  
Ion Storage ◽  
Product Ions ◽  
Ion Species ◽  
Kinetics Of

Resonant ejection of ion species from the quadrupole ion store (QUISTOR) is shown to reveal the coupling of reactant ions with product ions in ion/molecule reactions studied with the QUISTOR – quadrupole mass filter combination. The technique involves the use of selective ejection of a chosen ionic precursor and the simultaneous observation of the perturbations in the concentration of product ions. The technique is demonstrated in studies of the ion chemistry and reaction kinetics of two known chemical systems.

Gas phase ion–molecule reactions of dimethylsulphoxide

1978 ◽  
Vol 56 (17) ◽  
pp. 2324-2330 ◽  
Author(s):  
John Edward Fulford ◽  
Joseph Wayne Dupuis ◽  
Raymond Evans March
Keyword(s):  
Gas Phase ◽  
Ambient Pressure ◽  
Reaction Chamber ◽  
Ion Trapping ◽  
Ion Chemistry ◽  
Gas Phase Ion Chemistry ◽  
Molecule Reaction ◽  
Ion Molecule Reactions ◽  
Ion Storage ◽  
Gas Phase Ion

The gas phase ion-chemistry of dimethylsulphoxide (DMSO) and deuterated dimethylsulphoxide (DMSO-d6) has been examined using a quadrupole ion store (QUISTOR) as an ion–molecule reaction chamber. The QUISTOR results are compared with those obtained by ion trapping and high pressure mass spectrometry as reported by other workers. The performance of the QUISTOR demonstrates the versatility of the technique for ion–molecule reaction studies with variation of ambient pressure and duration of ion storage.

Mass Spectra and Ion Chemistry of Methylphosphine, Dimethylphosphine and Dimethyldeuterophosphine, Investigated by Ion Cyclotron Resonance Spectrometry

1975 ◽  
Vol 30 (3) ◽  
pp. 329-339 ◽  
Author(s):  
Karl-Peter Wanczek
Keyword(s):  
Rate Constants ◽  
Cyclotron Resonance ◽  
Mass Spectra ◽  
Ion Cyclotron Resonance ◽  
Exchange Reactions ◽  
Ion Chemistry ◽  
Ion Molecule Reactions ◽  
Ion Cyclotron ◽  
Product Ions ◽  
Ion Cyclotron Resonance Spectrometry

The mass spectra and the ion molecule reactions of methylphosphine, dimethylphosphine and dimethyldeuterophosphine have been studied by ion cyclotron resonance spectrometry. About 50 ion molecule reaction are observed for each compound. The product ions can be classified as ions with two phosphorus atoms: P2R5+, P2R3+, P2R2+ and P2R+ (R = CH3 or H), as phosphonium and phosphinium ions and ions resulting from collision dissociations and charge exchange reactions. Tertiary ions with three phosphorus atoms like CH3P3H2+ (from CH3PH2) and (CH3)4P3H2 (from (CH3)2PH) have also been detected. The mechanisms of the ion molecule reactions, rearrangements, P -H- and C-H-reactivities and product ion structures are discussed, using in the case of dimethylphosphine the results obtained with the deuterated compound. Rate constants of formation of the more abundant product ions from the molecular ion and the CH3P+ ion, both odd electron particles, have been determined. The reactions with dimethylphosphine have much smaller rate constants than the reactions with methylphosphine.

scholarly journals Chemical ionisation quadrupole mass spectrometer with an electrical discharge ion source for atmospheric trace gas measurement

2018 ◽  
Author(s):  
Philipp G. Eger ◽  
Frank Helleis ◽  
Gerhard Schuster ◽  
Gavin J. Phillips ◽  
Jos Lelieveld ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Mass Spectrometer ◽  
Ion Source ◽  
Quadrupole Mass Spectrometer ◽  
Rf Discharge ◽  
Data Sets ◽  
Quadrupole Mass ◽  
Ion Chemistry ◽  
Ion Molecule Reactions ◽  
Chemical Ionisation

Abstract. We present a Chemical Ionisation Quadrupole Mass Spectrometer (CI-QMS) with radio-frequency (RF) discharge ion source through N2/CH3I as source of primary ions. In addition to the expected detection of PAN, peracetic acid and ClNO2 through well-established ion-molecule-reactions with I- and its water cluster, the instrument is also sensitive to SO2, HCl and acetic acid (CH3C(O)OH) through additional ion chemistry unique for our ion source. We present ionisation schemes for detection of SO2, HCl and acetic acid along with illustrative data sets from three different field campaigns underlining the potential of the CI-QMS with an RF discharge ion source as an alternative to 210Po. The additional sensitivity to SO2 and HCl makes the CI-QMS suitable for investigating the role of sulphur and chlorine chemistry in the polluted marine and coastal boundary layer.

scholarly journals Dynamic Range Expansion by Gas-Phase Ion Fractionation and Enrichment for Imaging Mass Spectrometry

2020 ◽  
Author(s):  
Boone Prentice ◽  
Daniel Ryan ◽  
Kerri Grove ◽  
D. Shannon Cornett ◽  
Richard Caprioli ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Dynamic Range ◽  
Limit Of Detection ◽  
Imaging Mass Spectrometry ◽  
Quadrupole Mass Filter ◽  
Ion Accumulation ◽  
Quadrupole Mass ◽  
Mass Filter ◽  
Tissue Samples ◽  
Ion Species

In the analysis of biological tissue by imaging mass spectrometry (IMS), the limit of detection and dynamic range are of paramount importance in obtaining experimental results that provide insight into underlying biological processes. Many important biomolecules are present in the tissue milieu in low concentrations and in complex mixtures with other compounds of widely ranging abundances, challenging the limits of analytical technologies. In many IMS experiments, the ion signal can be dominated by a few highly abundant ion species. On trap-based instrument platforms that accumulate ions prior to mass analysis, these high abundance ions can diminish the detection and dynamic range of lower abundance ions. Herein, we characterize two strategies for combating these challenges during IMS experiments on a hybrid QqFT-ICR MS. In one iteration, the mass resolving capabilities of a quadrupole mass filter are used to selectively enrich for ions of interest via a technique previously termed continuous accumulation of selected ions (CASI). Secondly, we have introduced a supplemental dipolar AC waveform to the quadrupole mass filter of a commercial QqFT-ICR mass spectrometer to perform selected ion ejection prior to the ion accumulation region. This setup allows the selective ejection of the most abundant ion species prior to ion accumulation, thereby greatly improving the molecular depth with which IMS can probe tissue samples.<br>

scholarly journals Chemical ionization quadrupole mass spectrometer with an electrical discharge ion source for atmospheric trace gas measurement

2019 ◽  
Vol 12 (3) ◽  
pp. 1935-1954 ◽  
Author(s):  
Philipp G. Eger ◽  
Frank Helleis ◽  
Gerhard Schuster ◽  
Gavin J. Phillips ◽  
Jos Lelieveld ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Mass Spectrometer ◽  
Chemical Ionization ◽  
Ion Source ◽  
Quadrupole Mass Spectrometer ◽  
Rf Discharge ◽  
Quadrupole Mass ◽  
Ion Chemistry ◽  
Ion Molecule Reactions ◽  
Coastal Boundary Layer

Abstract. We present a chemical ionization quadrupole mass spectrometer (CI-QMS) with a radio-frequency (RF) discharge ion source through N2∕CH3I as a source of primary ions. In addition to the expected detection of PAN, peracetic acid (PAA) and ClNO2 through well-established ion–molecule reactions with I− and its water cluster, the instrument is also sensitive to SO2, HCl and acetic acid (CH3C(O)OH) through additional ion chemistry unique to our ion source. We present ionization schemes for detection of SO2, HCl and acetic acid along with illustrative datasets from three different field campaigns underlining the potential of the CI-QMS with an RF discharge ion source as an alternative to 210Po. The additional sensitivity to SO2 and HCl makes the CI-QMS suitable for investigating the role of sulfur and chlorine chemistry in the polluted marine and coastal boundary layer.

Ion Chemistry of Phosphirane and Structure of the Phosphirane Molecular Ion

1975 ◽  
Vol 30 (11) ◽  
pp. 1470-1475 ◽  
Author(s):  
Zdenek-Christian Profous ◽  
Karl-Peter Wanczek ◽  
Hermann Hartmann
Keyword(s):  
Transfer Reactions ◽  
Ion Cyclotron Resonance ◽  
Ring Extension ◽  
Ion Chemistry ◽  
Group Transfer ◽  
Molecular Ion ◽  
Ion Molecule Reactions ◽  
Product Ions ◽  
Ion Cyclotron Resonance Spectrometry ◽  
Almost All

The mass spectrum and the ion molecule reactions of phosphirane and of mixtures of phosphirane with NH3 , NH2D, NHD2 and ND3 have been studied by ion cyclotron resonance spectrometry. Almost all important product ions are formed by PH-group transfer reactions, where ethene is generated as the neutral particle. Only two of the more abundant ions, the protonated molecule, H2P(CH2)2+ and the ion m/e=63, P2H+, are formed via other reaction pathways. Secondary, tertiary and quarternary product ions with the general formula R(PH)n+ (R: phosphirane fragment, n-1, 2, 3) have been detected.The molecular ion is proved to have a cyclic structure. Two possible structures of the product ions with two and three phosphorus atoms are discussed: a structure with an open phosphorus chain, leaving the phosphirane ring intact and a ring extended structure, produced by a ring extension reaction of the PH-group.Several rate constants of the ion molecule reactions of the phosphirane molecular ion are given

scholarly journals Dynamic Range Expansion by Gas-Phase Ion Fractionation and Enrichment for Imaging Mass Spectrometry

2020 ◽  
Author(s):  
Boone Prentice ◽  
Daniel Ryan ◽  
Kerri Grove ◽  
D. Shannon Cornett ◽  
Richard Caprioli ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Dynamic Range ◽  
Limit Of Detection ◽  
Imaging Mass Spectrometry ◽  
Quadrupole Mass Filter ◽  
Ion Accumulation ◽  
Quadrupole Mass ◽  
Mass Filter ◽  
Tissue Samples ◽  
Ion Species

In the analysis of biological tissue by imaging mass spectrometry (IMS), the limit of detection and dynamic range are of paramount importance in obtaining experimental results that provide insight into underlying biological processes. Many important biomolecules are present in the tissue milieu in low concentrations and in complex mixtures with other compounds of widely ranging abundances, challenging the limits of analytical technologies. In many IMS experiments, the ion signal can be dominated by a few highly abundant ion species. On trap-based instrument platforms that accumulate ions prior to mass analysis, these high abundance ions can diminish the detection and dynamic range of lower abundance ions. Herein, we characterize two strategies for combating these challenges during IMS experiments on a hybrid QqFT-ICR MS. In one iteration, the mass resolving capabilities of a quadrupole mass filter are used to selectively enrich for ions of interest via a technique previously termed continuous accumulation of selected ions (CASI). Secondly, we have introduced a supplemental dipolar AC waveform to the quadrupole mass filter of a commercial QqFT-ICR mass spectrometer to perform selected ion ejection prior to the ion accumulation region. This setup allows the selective ejection of the most abundant ion species prior to ion accumulation, thereby greatly improving the molecular depth with which IMS can probe tissue samples.<br>

scholarly journals In situ Rb-Sr dating by collision cell, multicollection inductively-coupled plasma mass-spectrometry with pre-cell mass-filter, (CC-MC-ICPMS/MS).

2021 ◽  
Author(s):  
Dan Bevan ◽  
Christopher David Coath ◽  
Jamie Lewis ◽  
Johannes B Schwieters ◽  
Nicholas Selwyn Lloyd ◽  
...  
Keyword(s):  
Inductively Coupled Plasma ◽  
Cell Mass ◽  
Quadrupole Mass Filter ◽  
Collision Cell ◽  
Uv Laser ◽  
Quadrupole Mass ◽  
Mass Filter ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

We document the utility for in situ Rb-Sr dating of a one-of-a-kind tribrid mass spectrometer, ‘Proteus’, coupled to a UV laser ablation system. Proteus combines a pre-cell quadrupole mass-filter,collision cell,...

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