Preparation, infrared spectra, and crystal structure of two modifications of the (thymidinato-N3)methylmercury(II) complex
Reaction of CH3HgOH with thymidine (HT) yielded the neutral CH3HgT complex crystallizing as a hydrated or an anhydrous material, depending on preparation conditions. Both forms were examined by X-ray diffraction. The anhydrous variety is monoclinic, space group P21, a = 4.798(6), b = 14.270(8), c = 10.390(4) Å, β = 102.74(9)°, and Z = 2 molecules per cell. The structure was refined on 1552 nonzero MoKα reflections to a conventional R factor of 0.034. The hydrated form belongs to the orthorhombic space group P212121, a = 10.484(3), b = 14.633(3), c = 18.538(5), Z = 8. The structure was refined on 1816 nonzero MoKα reflections to R = 0.036. In both forms, the CH3Hg+ ion is linearly bonded to the deprotonated N(3) site of thymidine. The water molecules and hydroxyl groups in the ribose unit participate in a hydrogen bonding network, in which the carbonyl groups are involved as acceptors. The infrared spectra of the two forms differ significantly only by the absorptions due to the water molecules. By comparing with the spectrum of thymidine, diagnostic regions for complexation with deprotonated thymidine have been proposed