Chapter 5: Nanofibrous Scaffolds for Tissue Engineering Applications: State-of-the-Art and Future Trends

2014 ◽  
pp. 163-203
Author(s):  
Masoud Mozafari ◽  
Vahid Shabafrooz ◽  
Mostafa Yazdimamaghani ◽  
Daryoosh Vashaee ◽  
Lobat Tayebi
Keyword(s):  
Tissue Engineering ◽  
State Of The Art ◽  
Future Trends ◽  
Engineering Applications ◽  
Nanofibrous Scaffolds

The effect of silk gland sericin protein incorporation into electrospun polycaprolactone nanofibers on in vitro and in vivo characteristics

2015 ◽  
Vol 3 (5) ◽  
pp. 859-870 ◽  
Author(s):  
Linhao Li ◽  
Yuna Qian ◽  
Chongwen Lin ◽  
Haibin Li ◽  
Chao Jiang ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Silk Gland ◽  
Engineering Applications ◽  
Nanofibrous Scaffolds ◽  
Protein Incorporation

Silk middle gland extracted sericin protein based electrospun nanofibrous scaffolds with excellent biocompatibility have been developed for tissue engineering applications.

scholarly journals Immobilization of silk fibroin on the surface of PCL nanofibrous scaffolds for tissue engineering applications

2018 ◽  
Vol 135 (37) ◽  
pp. 46684 ◽  
Author(s):  
Alireza Khosravi ◽  
Laleh Ghasemi-Mobarakeh ◽  
Hossein Mollahosseini ◽  
Fatemeh Ajalloueian ◽  
Maryam Masoudi Rad ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Silk Fibroin ◽  
Engineering Applications ◽  
Nanofibrous Scaffolds

scholarly journals Improved cell infiltration of highly porous 3D nanofibrous scaffolds formed by combined fiber–fiber charge repulsions and ultra-sonication

2014 ◽  
Vol 2 (46) ◽  
pp. 8116-8122 ◽  
Author(s):  
Sung In Jeong ◽  
Nancy A. Burns ◽  
Christopher A. Bonino ◽  
Il Keun Kwon ◽  
Saad A. Khan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Infiltration ◽  
High Humidity ◽  
Post Processing ◽  
Engineering Applications ◽  
Nanofibrous Scaffolds ◽  
Highly Porous

Hydrogel mats with increased thickness and porosity were achieved by pairing high humidity electrospinning with post-processing ultra-sonication, and they show promise for the design of cell-permeable nanofibrous scaffolds for tissue-engineering applications.

scholarly journals Bone Tissue Engineering: State of the Art and Future Trends

2004 ◽  
Vol 4 (8) ◽  
pp. 743-765 ◽  
Author(s):  
António J. Salgado ◽  
Olga P. Coutinho ◽  
Rui L. Reis
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
State Of The Art ◽  
Future Trends ◽  
Engineering State

scholarly journals Tissue Engineering 3D Porous Scaffolds Prepared from Electrospun Recombinant Human Collagen (RHC) Polypeptides/Chitosan Nanofibers

2021 ◽  
Vol 11 (11) ◽  
pp. 5096
Author(s):  
Aipeng Deng ◽  
Yang Yang ◽  
Shimei Du
Keyword(s):  
Tissue Engineering ◽  
Three Dimensional ◽  
Great Promise ◽  
Porous Scaffolds ◽  
High Porosity ◽  
Engineering Applications ◽  
Nanofibrous Scaffolds ◽  
Human Collagen ◽  
Hierarchical Pore ◽  
Nih 3T3

Electrospinning, the only method that can continuously produce nanofibers, has been widely used to prepare nanofibers for tissue engineering applications. However, electrospinning is not suitable for preparing clinically relevant three-dimensional (3D) nanofibrous scaffolds with hierarchical pore structures. In this study, recombinant human collagen (RHC)/chitosan nanofibers prepared by electrospinning were combined with porous scaffolds produced by freeze drying to fabricate 3D nanofibrous scaffolds. These scaffolds exhibited high porosity (over 80%) and an interconnected porous structure (ranging from sub-micrometers to 200 μm) covered with nanofibers. As confirmed by the characterization results, these scaffolds showed good swelling ability, stability, and adequate mechanical strength, making it possible to use the 3D nanofibrous scaffolds in various tissue engineering applications. In addition, after seven days of cell culturing, NIH 3T3 was infiltrated into the scaffolds while maintaining its morphology and with superior proliferation and viability. These results indicated that the 3D nanofibrous scaffolds hold great promise for tissue engineering applications.

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